Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Linda S. Resar"'
Autor:
Jerry L Spivak, Akil Merchant, Donna M Williams, Ophelia Rogers, Wanke Zhao, Amy Duffield, Linda S Resar, Alison R Moliterno, Zhizhuang J Zhao
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0232801 (2020)
The myeloproliferative neoplasms, polycythemia vera, essential thrombocytosis and primary myelofibrosis are hematopoietic stem cell disorders and share driver mutations that either directly activate the thrombopoietin receptor, MPL, or activate it in
Externí odkaz:
https://doaj.org/article/e50e6b55a5c045599a6aaacfc14d5345
Autor:
Wanke Zhao, Akil Merchant, Donna M. Williams, Jerry L. Spivak, Linda S. Resar, Alison R. Moliterno, Zhizhuang Joe Zhao, Ophelia Rogers, Amy S. Duffield
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0232801 (2020)
PLoS ONE, Vol 15, Iss 6, p e0232801 (2020)
The myeloproliferative neoplasms, polycythemia vera, essential thrombocytosis and primary myelofibrosis are hematopoietic stem cell disorders and share driver mutations that either directly activate the thrombopoietin receptor, MPL, or activate it in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0ac1a63c8d6bb8c04e50a61ce44c19
http://europepmc.org/articles/PMC7263591
http://europepmc.org/articles/PMC7263591
Autor:
Karen L. Reddy, Mikhail Gorbounov, Linda S. Resar, Briyana Chisholm, Mohammad Heydarian, Dorhyun Johng, Lingling Xian, Guangjing Zhu, Lionel Chia, William B. Isaacs
Publikováno v:
Cancer Research. 79:2595-2595
While High Mobility Group A1 (HMGA1) chromatin remodeling proteins are frequently dysregulated in diverse cancers, their molecular underpinnings in carcinogenesis remain poorly understood. HMGA1 are small, non-histone proteins that bind to AT-rich re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7abb1262931eb0e0e056a18732a57419
https://doi.org/10.1158/1538-7445.am2019-2595
https://doi.org/10.1158/1538-7445.am2019-2595
Autor:
Kirti Shetty, Chu-Xia Deng, Wilma S. Jogunoori, Richard Amdur, Linda S. Resar, Patricia Latham, Raja Mazumder, Anelia Horvath, Bao-Ngoc Nguyen, Shulin Li, Xifeng Wu, Herbert Yu, Linda L. Wong, Jon White, Sylvia Silver, Asif Rashid, Vikas Kundra, Xin Wei Wang, Lopa Mishra
Publikováno v:
Cancer Research. 79:3156-3156
In its early stages, HCC is curable; once advanced, HCC is associated with high mortality. HCC is associated with alterations in key driving pathways, including the Wnt pathway, TGF-β pathway, the p53 pathway, and pathways that regulate Myc activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d1fc936284b720d681c5692ecd54275
https://doi.org/10.1158/1538-7445.am2019-3156
https://doi.org/10.1158/1538-7445.am2019-3156
Autor:
Jon White, Chu-Xia Deng, Vikas Kundra, Xin Wei Wang, Kirti Shetty, Anelia Horvath, Patricia S. Latham, Raja Mazumder, Herbert Yu, Shuyun Rao, Wilma Jogunoori, Shulin Li, Asif Rashid, Linda S. Resar, Lopa Mishra, Linda L. Wong, Richard Amdur, Bao-Ngoc Nguyen, Sobia Zaidi
Publikováno v:
Gastroenterology. 156:S-1306
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca74de2122dc44b309bac0665e6eb227
https://doi.org/10.1016/s0016-5085(19)40276-x
https://doi.org/10.1016/s0016-5085(19)40276-x
Publikováno v:
Analytical and Bioanalytical Chemistry. 405:5013-5030
Metabolomics is coming of age as an important area of investigation which may help reveal answers to questions left unanswered or only partially understood from proteomic or genomic approaches. Increased knowledge of the relationship of genes and pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc733b51ff5b32f53b5ffd30b20f5a4
https://doi.org/10.1007/s00216-013-6777-5
https://doi.org/10.1007/s00216-013-6777-5
Autor:
Jacqueline Greer, Judith E. Karp, Dwella Moton-Nelson, Biju Joseph, Steven D. Gore, Hetty E. Carraway, Amanda L. Blackford, John J. Wright, Katrina Alino, Linda S. Resar, Janet Briel, Michael A. McDevitt, B. Douglas Smith, Mark J. Levis, Karen Mackey, L. Austin Doyle, Lorena Bagain, Ming Zhao, Michelle A. Rudek
Publikováno v:
Blood. 117:3302-3310
Flavopiridol is a protein bound, cytotoxic, cyclin-dependent kinase inhibitor. Flavopiridol given by 1-hour bolus at 50 mg/m2 daily 3 times followed by cytosine arabinoside and mitoxantrone (FLAM) is active in adults with poor-risk acute leukemias. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dffa59c85be1a51405eec7aee2ca237
https://doi.org/10.1182/blood-2010-09-310862
https://doi.org/10.1182/blood-2010-09-310862
Autor:
Linda S. Resar, William B. Issacs, Guangjing Zhu, Mohammad Heydarian, Lionel Chia, Lingling Xian, Karen L. Reddy
Publikováno v:
Cancer Research. 78:3352-3352
Increasing evidence suggests that cancer cells undergo chromatin remodeling and epigenetic reprogramming during tumor progression, although the underlying mechanisms remain poorly understood. The High Mobility Group A1 (HMGA1) chromatin binding prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a144c7366fafc1725ccf171dd9376d03
https://doi.org/10.1158/1538-7445.am2018-3352
https://doi.org/10.1158/1538-7445.am2018-3352
Publikováno v:
Cancer Research. 78:4494-4494
Pancreatic ductal adenocarcinomas (PDACs) are highly lethal tumors for which there are no effective therapies. Emerging evidence suggests that the tumor stroma interacts with the cancer cells to induce cancer stem cell properties and drive tumor prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa39dd7eade476a918a5063d6be5e20c
https://doi.org/10.1158/1538-7445.am2018-4494
https://doi.org/10.1158/1538-7445.am2018-4494
Autor:
Joelle Hillion, Mohammad Heydarian, Michael Koo, Leslie Cope, Sujayita Roy, David L. Huso, Brigitte M. Ronnett, Li Z. Luo, Karen L. Reddy, Linda S. Resar, Deborah K. Armstrong, Tait Huso, Lingling Xian, Kathleen Kellyn
Publikováno v:
Gynecologic oncology. 141(3)
Objectives Although uterine cancer is the fourth most common cause for cancer death in women worldwide, the molecular underpinnings of tumor progression remain poorly understood. The High Mobility Group A1 ( HMGA1 ) gene is overexpressed in aggressiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70ae848a5c78406163f4bf8d38f9973
https://pubmed.ncbi.nlm.nih.gov/27001612
https://pubmed.ncbi.nlm.nih.gov/27001612