Výsledky vyhledávání - "Linda S. Ahn"

Brief Report: Combination of Osimertinib and Dacomitinib to Mitigate Primary and Acquired Resistance in EGFR-Mutant Lung Adenocarcinomas

Autor: Arielle Elkrief, Alex Makhnin, Khadeja A. Moses, Linda S. Ahn, Isabel R. Preeshagul, Afsheen N. Iqbal, Sara A. Hayes, Andrew J. Plodkowski, Paul K. Paik, Marc Ladanyi, Mark G. Kris, Gregory J. Riely, Franziska Michor, Helena A. Yu

Publikováno v: Clinical Cancer Research. 29:1423-1428

Purpose: Primary and acquired resistance to osimertinib remain significant challenges for patients with EGFR-mutant lung cancers. Acquired EGFR alterations such as EGFR T790M or C797S mediate resistance to EGFR tyrosine kinase inhibitors (TKI) and co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54f4f625ed5f97d1b7e414751e5f95a4
https://doi.org/10.1158/1078-0432.ccr-22-3484

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Supplemental Figure 1 from Brief Report: Combination of Osimertinib and Dacomitinib to Mitigate Primary and Acquired Resistance in EGFR-Mutant Lung Adenocarcinomas

Autor: Helena A. Yu, Franziska Michor, Gregory J. Riely, Mark G. Kris, Marc Ladanyi, Paul K. Paik, Andrew J. Plodkowski, Sara A. Hayes, Afsheen N. Iqbal, Isabel R. Preeshagul, Linda S. Ahn, Khadeja A. Moses, Alex Makhnin, Arielle Elkrief

Supplemental Figure 1. Dose modifications of Combination Osimertinib and Dacomitinib (initial therapy study).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c64047c576307a4e9d5e188c4c469b
https://doi.org/10.1158/1078-0432.22632971.v1

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Supplemental Figure 4 from Brief Report: Combination of Osimertinib and Dacomitinib to Mitigate Primary and Acquired Resistance in EGFR-Mutant Lung Adenocarcinomas

Supplemental Figure 4. A. Median progression-free survival and B. Overall survival for patients enrolled in the acquired resistance study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d58e9d9523326d1f9db1fbe06b7815
https://doi.org/10.1158/1078-0432.22632962.v1

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Supplemental Figure 3 from Brief Report: Combination of Osimertinib and Dacomitinib to Mitigate Primary and Acquired Resistance in EGFR-Mutant Lung Adenocarcinomas

Supplemental Figure 3. A. Median progression-free survival and B. Overall survival for patients enrolled in the initial therapy study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1787c7367d2892ace2a1d49ed62c869c
https://doi.org/10.1158/1078-0432.22490464

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Supplemental Figure 2 from Brief Report: Combination of Osimertinib and Dacomitinib to Mitigate Primary and Acquired Resistance in EGFR-Mutant Lung Adenocarcinomas

Supplemental Figure 2. Dose modifications of Dacomitinib +/- Osimertinib (acquired resistance study).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e1611fe736d1bb322b395996ea6b5f
https://doi.org/10.1158/1078-0432.22490467

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Supplementary Table 1 from Brief Report: Combination of Osimertinib and Dacomitinib to Mitigate Primary and Acquired Resistance in EGFR-Mutant Lung Adenocarcinomas

Supplemental Table 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9da03b1490517c4381387ca858292b
https://doi.org/10.1158/1078-0432.22490458

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Pilot Study of Dacomitinib for Patients With Metastatic EGFR-Mutant Lung Cancers With Disease Progression After Initial Treatment With Osimertinib

Autor: Yosef Tobi, Sara A. Hayes, Isabel R Preeshagul, Afsheen Iqbal, Mark G. Kris, Glenn Heller, Noura J. Choudhury, Robert M Daly, Helena A. Yu, Alex Makhnin, Linda S Ahn, Gregory J Riely

Publikováno v: JCO Precision Oncology. :695-700

PURPOSE Patients with EGFR-mutant lung cancer have no approved targeted therapies after disease progression on first-line osimertinib, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). Preclinical studies sug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8b59aa49acc6e8902bb1fed639f76a0
https://doi.org/10.1200/po.21.00005

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Clinical outcomes of systemic therapy for patients with deep fibromatosis (desmoid tumor)

Autor: Mary Louise Keohan, Linda S. Ahn, Cristina R. Antonescu, Murray F. Brennan, Robert G. Maki, David R. D'Adamo, Samuel Singer, Veridiana Pires de Camargo

Publikováno v: Cancer.

BACKGROUND: In the current study, the authors examined the outcomes of patients with desmoid tumors who received systemic therapy at a single institution to provide a basis for the examination of newer agents. METHODS: Records of patients with desmoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4b3b3e280f4b446612053eccfa0014
https://doi.org/10.1002/cncr.25089

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