Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Linda Rubinstein"'
Autor:
Marissa Burke, Kelly Wong, Yuli Talyansky, Siddhita D. Mhatre, Carol Mitchell, Cassandra M. Juran, Makaila Olson, Janani Iyer, Stephanie Puukila, Candice G. T. Tahimic, Lane K. Christenson, Moniece Lowe, Linda Rubinstein, Yasaman Shirazi-Fard, Marianne B. Sowa, Joshua S. Alwood, April E. Ronca, Amber M. Paul
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Exposure to cosmic ionizing radiation is an innate risk of the spaceflight environment that can cause DNA damage and altered cellular function. In astronauts, longitudinal monitoring of physiological systems and interactions between these sy
Externí odkaz:
https://doaj.org/article/a49ceff1b5d94721b1f2bc6e8f711071
Autor:
Stephanie Puukila, Olivia Siu, Linda Rubinstein, Candice G. T. Tahimic, Moniece Lowe, Steffy Tabares Ruiz, Ivan Korostenskij, Maya Semel, Janani Iyer, Siddhita D. Mhatre, Yasaman Shirazi-Fard, Joshua S. Alwood, Amber M. Paul, April E. Ronca
Publikováno v:
Life, Vol 13, Iss 5, p 1214 (2023)
Exposure to space galactic cosmic radiation is a principal consideration for deep space missions. While the effects of space irradiation on the nervous system are not fully known, studies in animal models have shown that exposure to ionizing radiatio
Externí odkaz:
https://doaj.org/article/783b8f85f80648558e9d9925d3da7f2f
Autor:
Linda Rubinstein, Ann-Sofie Schreurs, Samantha M. Torres, Sonette Steczina, Moniece G. Lowe, Frederico Kiffer, Antiño R. Allen, April E. Ronca, Marianne B. Sowa, Ruth K. Globus, Candice G. T. Tahimic
Publikováno v:
npj Microgravity, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Isolation on Earth can alter physiology and signaling of organs systems, including the central nervous system. Although not in complete solitude, astronauts operate in an isolated environment during spaceflight. In this study, we determined
Externí odkaz:
https://doaj.org/article/3e9da7ae8c2a4834b6f11f00fed4c348
Autor:
Linda Rubinstein, Frederico Kiffer, Stephanie Puukila, Moniece G. Lowe, Brie Goo, Amalia Luthens, Ann-Sofie Schreurs, Samantha M. Torres, Sonette Steczina, Candice G. T. Tahimic, Antiño R. Allen
Publikováno v:
Life, Vol 12, Iss 11, p 1838 (2022)
Microgravity (modeled by head-tilt bedrest and hind-limb unloading), experienced during prolonged spaceflight, results in neurological consequences, central nervous system (CNS) dysfunction, and potentially impairment during the performance of critic
Externí odkaz:
https://doaj.org/article/a238ffcabf174beaa0b5206b859522b7
Autor:
Candice G. T. Tahimic, Amber M. Paul, Ann-Sofie Schreurs, Samantha M. Torres, Linda Rubinstein, Sonette Steczina, Moniece Lowe, Sharmila Bhattacharya, Joshua S. Alwood, April E. Ronca, Ruth K. Globus
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
The hindlimb unloading (HU) model has been used extensively to simulate the cephalad fluid shift and musculoskeletal disuse observed in spaceflight with its application expanding to study immune, cardiovascular and central nervous system responses, a
Externí odkaz:
https://doaj.org/article/259c5e8237774417acb4f6a047182e50
Autor:
Linda Rubinstein, Amber M. Paul, Charles Houseman, Metadel Abegaz, Steffy Tabares Ruiz, Nathan O’Neil, Gilad Kunis, Racheli Ofir, Jacob Cohen, April E. Ronca, Ruth K. Globus, Candice G. T. Tahimic
Publikováno v:
Cells, Vol 10, Iss 4, p 940 (2021)
Long duration spaceflight poses potential health risks to astronauts during flight and re-adaptation after return to Earth. There is an emerging need for NASA to provide successful and reliable therapeutics for long duration missions when capability
Externí odkaz:
https://doaj.org/article/2e945b4dc5e846eb9a2fe56fc2cf10d8
Autor:
Gal Hagit Romano, Yaniv Harari, Tal Yehuda, Ariel Podhorzer, Linda Rubinstein, Ron Shamir, Assaf Gottlieb, Yael Silberberg, Dana Pe'er, Eytan Ruppin, Roded Sharan, Martin Kupiec
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003721 (2013)
Telomeres protect the chromosome ends from degradation and play crucial roles in cellular aging and disease. Recent studies have additionally found a correlation between psychological stress, telomere length, and health outcome in humans. However, st
Externí odkaz:
https://doaj.org/article/4cc49b45cb86402d85444e950978728e
Publikováno v:
PLoS Genetics, Vol 7, Iss 12, p e1002421 (2011)
Externí odkaz:
https://doaj.org/article/3b62dc3dea6b402a9f186d8673c7dc0c
Autor:
Ruth K. Globus, Moniece Lowe, Linda Rubinstein, Joshua S. Alwood, Stephanie Puukila, Amber M. Paul, Siddhita D. Mhatre, Candice Tahimic, Janani Iyer, Sharmila Bhattacharya, Marianne B. Sowa, April E. Ronca
Publikováno v:
Neuroscience & Biobehavioral Reviews. 132:908-935
As human space exploration advances to establish a permanent presence beyond the Low Earth Orbit (LEO) with NASA’s Artemis mission, researchers are striving to understand and address the health challenges of living and working in the spaceflight en
Autor:
Candice Tahimic, Sonette Steczina, Antiño R. Allen, Ruth K. Globus, Frederico Kiffer, Marianne B. Sowa, Moniece Lowe, April E. Ronca, Ann-Sofie Schreurs, Samantha Torres, Linda Rubinstein
Publikováno v:
NPJ Microgravity
npj Microgravity, Vol 7, Iss 1, Pp 1-9 (2021)
npj Microgravity, Vol 7, Iss 1, Pp 1-9 (2021)
Isolation on Earth can alter physiology and signaling of organs systems, including the central nervous system. Although not in complete solitude, astronauts operate in an isolated environment during spaceflight. In this study, we determined the effec