Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Linda Rolf"'
Autor:
Max Mimpen, Linda Rolf, Geert Poelmans, Jody van den Ouweland, Raymond Hupperts, Jan Damoiseaux, Joost Smolders
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261097 (2021)
IntroductionA poor 25-hydroxyvitamin D (25(OH)D) status is a much replicated risk factor for developing multiple sclerosis (MS), and several vitamin D-associated single nucleotide polymorphisms (SNPs) have been associated with a higher risk of MS. Ho
Externí odkaz:
https://doaj.org/article/f827a9d52e434426987351e200564164
Autor:
Linda Rolf, Jan Damoiseaux, Inge Huitinga, Dorien Kimenai, Jody van den Ouweland, Raymond Hupperts, Joost Smolders
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
IntroductionMultiple sclerosis (MS) has been associated with both a poor vitamin D status and hyperactivity of the hypothalamus–pituitary–adrenal (HPA) axis. Since nuclear receptor ligands may regulate each other, we explored the association of v
Externí odkaz:
https://doaj.org/article/d6ddb8b3a2f24f3aabc25ccc58b8a1a4
Autor:
Anne-Hilde Muris, Joost Smolders, Linda Rolf, Lieke J J Klinkenberg, Noreen van der Linden, Steven Meex, Jan Damoiseaux, Raymond Hupperts
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156122 (2016)
BACKGROUND AND OBJECTIVE:The risk of developing multiple sclerosis (MS) as well as MS disease activity is associated with vitamin D (25(OH)D) status. The relationship between the main functional disability hallmark of MS, disability progression, and
Externí odkaz:
https://doaj.org/article/4b769758b9d74de4b72a95556573071d
Autor:
Anne-Hilde Muris, Oliver Gerlach, Jan Damoiseaux, Joost Smolders, Max Mimpen, Linda Rolf, Raymond Hupperts, Jens Kuhle
Publikováno v:
European Journal of Neurology
European Journal of Neurology, 28(3), 901-909. Wiley-Blackwell Publishing Ltd
European Journal of Neurology, 28(3), 901-909. Wiley
European Journal of Neurology, 28(3), 901-909. Wiley-Blackwell Publishing Ltd
European Journal of Neurology, 28(3), 901-909. Wiley
Background and purpose Natural killer (NK) cells may play a role in multiple sclerosis (MS). Ratios of NK cells to CD4+ T cells have been proposed as a biomarker for the therapeutic effect of stem cell transplantation in MS. The objectives here were
Autor:
Linda Rolf, Raymond Hupperts, Max Mimpen, Jan Damoiseaux, Oliver Gerlach, William P. T. M. van Doorn, Marvin M van Luijn, Joost Smolders, Anne-Hilde Muris
Publikováno v:
Journal of Neuroimmunology, 358. Elsevier B.V.
Journal of Neuroimmunology, 358:577664. Elsevier
Journal of Neuroimmunology, 358:577664. Elsevier
B-cells contribute to MS pathogenesis. The association of circulating B-cell phenotypes with combined unique active lesions (CUA) on MRI at 48 weeks follow-up was investigated in 50 interferon beta-treated MS patients. Transitional B-cell proportions
Autor:
Geert Poelmans, Joost Smolders, Max Mimpen, Anne-Hilde Muris, Jan Damoiseaux, Oliver Gerlach, Linda Rolf, Raymond Hupperts
Publikováno v:
Journal of Neuroimmunology, 353:577499. Elsevier
Journal of Neuroimmunology, 353
Journal of Neuroimmunology, 353. Elsevier B.V.
Journal of Neuroimmunology, 353
Journal of Neuroimmunology, 353. Elsevier B.V.
NK/T-cell ratios predict disease activity in relapsing remitting multiple sclerosis (RRMS). We investigated in 50 RRMS patients whether interleukin-2 receptor alpha-chain (IL-2Rα) expression and shedding associates with NK/T-cell balance, as suggest
Autor:
Geert Poelmans, Max Mimpen, Linda Rolf, Jan Damoiseaux, Raymond Hupperts, Jody van den Ouweland, Joost Smolders
Publikováno v:
PLoS One, 16
PLoS One, 16, 12
PLoS ONE
PLOS ONE, 16(12):e0261097. Public Library of Science
PLoS ONE, 16(12 December):e0261097. Public Library of Science
PLoS ONE, Vol 16, Iss 12, p e0261097 (2021)
PLoS One, 16(12). Public Library of Science
PLoS One, 16, 12
PLoS ONE
PLOS ONE, 16(12):e0261097. Public Library of Science
PLoS ONE, 16(12 December):e0261097. Public Library of Science
PLoS ONE, Vol 16, Iss 12, p e0261097 (2021)
PLoS One, 16(12). Public Library of Science
Introduction A poor 25-hydroxyvitamin D (25(OH)D) status is a much replicated risk factor for developing multiple sclerosis (MS), and several vitamin D-associated single nucleotide polymorphisms (SNPs) have been associated with a higher risk of MS. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576a0486e22b163b43d4a5d6589ff4d1
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/244323
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/244323
Autor:
Sreeram V. Ramagopalan, Jan Damoiseaux, Giulio Disanto, Renaud Du Pasquier, Anne-Hilde Muris, Jens Kuhle, Amandine Mathias, Inga Koneczny, Joost Smolders, Linda Rolf, Raymond Hupperts
Publikováno v:
Multiple Sclerosis Journal, 24(10), 1280-1287. SAGE Publications Ltd
Multiple sclerosis, vol. 24, no. 10, pp. 1280-1287
Multiple sclerosis, vol. 24, no. 10, pp. 1280-1287
Background: Epstein–Barr virus (EBV) infection and vitamin D insufficiency are potentially interacting risk factors for multiple sclerosis (MS). Objectives: To investigate the effect of high-dose vitamin D3 supplements on antibody levels against th
Publikováno v:
Journal of the Neurological Sciences, 378, 30-35. Elsevier Science
Depressive symptoms are common in multiple sclerosis (MS), and both depression and MS have been associated with a poor vitamin D status. As cytokine-mediated inflammatory processes play a role in the pathogenesis of both disorders, we hypothesized th
Publikováno v:
Journal of Steroid Biochemistry and Molecular Biology, 164, 254-257. Elsevier Science
Low circulating 25-hydroxyvitamin D (25(OH)D) levels have been associated with an increased risk of relapses in relapsing remitting multiple sclerosis (RRMS), but an association with disability progression is uncertain. Lower 25(OH)D levels are found