Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Linda R. Brougham"'
Autor:
Craig P. Smith, Larry Davis, Francis P. Huger, Richard C. Effland, Linda R. Brougham, Joseph Thomas Klein
Publikováno v:
Drug Development Research. 30:203-212
It has been shown that a single injection of N-(n-propyl)-N-(3-fluoro-4-pyridinyl-1H-3-methylindol-1-amine hydrochloride) (HP 184) (0.6-4.8 mg/kg, or 2-15 μmoles/kg, sc) reversed passive avoidance deficits in rats with combined cholinergic and norad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c413dc907a87fbcc984e8cea64872e7b
https://doi.org/10.1002/ddr.430300402
https://doi.org/10.1002/ddr.430300402
Publikováno v:
Drug Development Research. 29:262-270
The enhancement of acetylcholine (ACh) release during electrical or potassium depolarization was compared in the presence of either linopirdine or 4-aminopyridine (4-AP) using two different functional assays. We measured ACh and choline (Ch) directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8f558d6b8ef0c4900ded57618fb5fa0
https://doi.org/10.1002/ddr.430290403
https://doi.org/10.1002/ddr.430290403
Publikováno v:
Journal of Medicinal Chemistry. 23:977-980
The synthesis of 8-(methoxyphenyl)-1,2,3,4-tetrahydroisoquinolines using aryloxazolines as key intermediates is described. Nucleophilic displacement on an o-methoxyphenyloxazoline by an aryl Grignard reagent, followed by electrophilic substitution at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226a365e1c9b3514bd9f200828abee8e
https://doi.org/10.1021/jm00183a003
https://doi.org/10.1021/jm00183a003
Autor:
George A. Clay, Linda R. Brougham
Publikováno v:
Biochemical Pharmacology. 24:1363-1367
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66948a6a009af7a962fc28e49aaafa4
https://doi.org/10.1016/0006-2952(75)90356-1
https://doi.org/10.1016/0006-2952(75)90356-1
Publikováno v:
Chemischer Informationsdienst. 12
The synthesis of 8-(methoxyphenyl)-1,2,3,4-tetrahydroisoquinolines using aryloxazolines as key intermediates is described. Nucleophilic displacement on an o-methoxyphenyloxazoline by an aryl Grignard reagent, followed by electrophilic substitution at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83c765ec23e2c09493f8ea24708b0914
https://doi.org/10.1002/chin.198109256
https://doi.org/10.1002/chin.198109256
Publikováno v:
Chemischer Informationsdienst. 10
A number of molecular similarities between the antipsychotic agents butaclamol and clozapine were noted. Based on the premise that this was a strong indicator of a common mechanism of action (i.e., binding at the antagonist state of the dopamine rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::294ff7cc6098f5a747e9c7509f50155c
https://doi.org/10.1002/chin.197934225
https://doi.org/10.1002/chin.197934225
Publikováno v:
Journal of medicinal chemistry. 22(4)
A number of molecular similarities between the antipsychotic agents butaclamol and clozapine were noted. Based on the premise that this was a strong indicator of a common mechanism of action (i.e., binding at the antagonist state of the dopamine rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7252027e3a172b5f7d75408e66339808
https://pubmed.ncbi.nlm.nih.gov/34721
https://pubmed.ncbi.nlm.nih.gov/34721
Publikováno v:
Journal of chromatography. 383(2)
A high-performance liquid chromatographic method for the analysis of chlorhexidine in human serum and urine was developed. Chlorhexidine and the internal standard, chlorpheniramine, were extracted into chloroform, containing 5% 2-propanol, and back-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124b285bd910c2c0708714a4b134a5e9
https://pubmed.ncbi.nlm.nih.gov/3558566
https://pubmed.ncbi.nlm.nih.gov/3558566