Zobrazeno 1 - 10
of 727
pro vyhledávání: '"Linda R Watkins"'
Autor:
Jayson B. Ball, Connor J. McNulty, Suzanne M. Green-Fulgham, Joseph M. Dragavon, Igor R. Correia Rocha, Maggie R. Finch, Emily D. Prévost, Imaad I. Siddique, Brodie J. Woodall, Linda R. Watkins, Michael V. Baratta, David H. Root
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
A challenge for central nervous system (CNS) tissue analysis in neuroscience research has been the difficulty to codetect and colocalize gene and protein expression in the same tissue. Given the importance of identifying gene expression relative to p
Externí odkaz:
https://doaj.org/article/853326147cf740d7bc6e261533903e46
Autor:
Andrew J. Kwilasz, Madison A. Clements, Tracey A. Larson, Kevin M. Harris, Scott T. Litwiler, Brodie J. Woodall, Laurel S. Todd, Anouk E. W. Schrama, Eric H. Mitten, Steven F. Maier, Anne-Marie Van Dam, Kenner C. Rice, Linda R. Watkins
Publikováno v:
Frontiers in Pain Research, Vol 3 (2022)
Up to 92% of patients suffering from multiple sclerosis (MS) experience pain, most without adequate treatment, and many report pain long before motor symptoms associated with MS diagnosis. In the most commonly studied rodent model of MS, experimental
Externí odkaz:
https://doaj.org/article/f69561aa0381439c90004b4abc048684
Autor:
Alice A. Larson
Publikováno v:
Journal of Musculoskeletal Pain. 16:358-359
Fifty-two authors with expertise and research interest in the areas of immunology, neuroscience, and medicine have joined forces under the editorial board of three outstanding researchers in the fi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b815e89978579e57773349a8f40d746
https://doi.org/10.1080/10582450802479750
https://doi.org/10.1080/10582450802479750
Autor:
Hongyuan Li, Yinghua Peng, Cong Lin, Xiaozheng Zhang, Tianshu Zhang, Yibo Wang, Yuanpeng Li, Siru Wu, Hongshuang Wang, Mark R. Hutchinson, Linda R. Watkins, Xiaohui Wang
Publikováno v:
The Innovation, Vol 2, Iss 2, Pp 100111- (2021)
Nicotine is the principal alkaloid of tobacco often manufactured into cigarettes and belongs to a highly addictive class of drugs. Nicotine attenuates the neuroinflammation induced by microglial activation. However, the molecular target(s) underlying
Externí odkaz:
https://doaj.org/article/f3383c10e3014292912d72c6a373fc52
Publikováno v:
PAIN Reports, Vol 6, Iss 1, p e905 (2021)
Abstract. Chronic pain is an unpleasant and debilitating condition that is often poorly managed by existing therapeutics. Reciprocal interactions between the nervous system and the immune system have been recognized as playing an essential role in th
Externí odkaz:
https://doaj.org/article/d68e8e6c7857418e9c20eaefced0f1ad
Publikováno v:
Neurobiology of Disease, Vol 132, Iss , Pp - (2019)
TAR-DNA binding protein 43 (TDP-43) is a multifunctional RNA binding protein directly implicated in the etiology of amyotrophic lateral sclerosis (ALS). Previous studies have demonstrated that loss of TDP-43 function leads to intracellular accumulati
Externí odkaz:
https://doaj.org/article/3eec52716bdc4c29981471203c340e11
Autor:
Nabanita Das, Varun Dewan, Peter M. Grace, Robin J. Gunn, Ryo Tamura, Netanel Tzarum, Linda R. Watkins, Ian A. Wilson, Hang Yin
Publikováno v:
Cell Reports, Vol 17, Iss 4, Pp 1128-1140 (2016)
Infectious and sterile inflammatory diseases are correlated with increased levels of high mobility group box 1 (HMGB1) in tissues and serum. Extracellular HMGB1 is known to activate Toll-like receptors (TLRs) 2 and 4 and RAGE (receptor for advanced g
Externí odkaz:
https://doaj.org/article/e602c673df734870a6cf62b00c8db8d4
Publikováno v:
Neurobiology of Stress, Vol 4, Iss C, Pp 62-70 (2016)
Stress and glucocorticoids (GCs) have universally been considered to be anti-inflammatory, however in recent years, stress and GCs have been found to exert permissive effects (immunological priming) on neuroinflammatory processes. This phenomenon of
Externí odkaz:
https://doaj.org/article/bc40027345a340f58cefee357f6b7d42
Autor:
Suzanne M. Green-Fulgham, Michael E. Harland, Jayson B. Ball, Jiahe Li, Michael J. Lacagnina, Heather D'Angelo, Renee A. Dreher, Kendal F. Willcox, Sabina A. Lorca, Andrew J. Kwilasz, Steven F. Maier, Linda R. Watkins, Peter M. Grace
Publikováno v:
Pain. 163:1939-1951
Animal and human studies have shown that exercise prior to nerve injury prevents later chronic pain, but the mechanisms of such preconditioning remain elusive. Given that exercise acutely increases the formation of free radicals, triggering antioxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9426a45a41a52f9e1117fa276bc989
https://doi.org/10.1097/j.pain.0000000000002589
https://doi.org/10.1097/j.pain.0000000000002589
Publikováno v:
Progress in neurobiology. 218
Microglia shape synaptic connections among neurons of the central nervous system (CNS) during development and adulthood. In this review, the actions by which they facilitate pruning, refinement, and new synaptic development throughout the lifespan ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4daf785506ae77427ae7481c1dc61a4
https://pubmed.ncbi.nlm.nih.gov/35940391
https://pubmed.ncbi.nlm.nih.gov/35940391