Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Linda R Bressler"'
Autor:
Susan Halabi, Jinyi Zhou, Yijie He, Linda R Bressler, Adrian F Hernandez, Nicholas A Turner, Hwanhee Hong
Publikováno v:
Clinical trials (London, England). 19(5)
Background/Aim The number of coronavirus disease 2019 deaths and cases continues to increase globally. Novel therapies are urgently needed to treat patients with coronavirus disease 2019. We sought to provide a critical review of trials designed duri
Autor:
Linda R. Bressler, Katie E. Long, J. Lee Villano, Nathalie Letarte, Michael Gabay, Joan M. Stachnik
Publikováno v:
Journal of Neuro-Oncology. 120:111-115
The EORTC-NCIC regimen for glioblastoma requires different dosing of temozolomide (TMZ) during radiation and maintenance therapy. This complexity is exacerbated by the availability of multiple TMZ capsule strengths. TMZ is an alkylating agent and the
Autor:
Rishi Lulla, Paul G. Fisher, Craig W. Beattie, Shengjie Wu, Girish Dhall, Arzu Onar, Roger J. Packer, Stewart Goldman, Tohru Yamada, Maryam Fouladi, Ira J. Dunkel, Michael J. Pacini, Linda R. Bressler, Ian F. Pollack, James M. Boyett
Background p53 is a promising target in human cancer. p28 is a cell-penetrating peptide that preferentially enters cancer cells and binds to both wild-type and mutant p53 protein, inhibiting COP1-mediated ubiquitination and proteasomal degradation. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1ad24dac578e918a737cc0662c784b
https://europepmc.org/articles/PMC4999001/
https://europepmc.org/articles/PMC4999001/
Publikováno v:
Annals of Pharmacotherapy. 43:235-241
Background: Serum creatinine (SCr)-based formulas are used to estimate glomerular filtration rate (GFR) when calculating a dosage for carboplatin using the Calvert equation, but these formulas often underestimate measured GFR. The Modified Diet in Re
Autor:
Joan M. Stachnik, Colleen L. Overley, Michael Gabay, Katie E. Long, Linda R. Bressler, John L. Villano, Scott Wirth
Publikováno v:
CNS drugs. 29(11)
The purpose of our review is to summarize the clinical activity of oral targeted agents against brain metastases. This includes BRAF inhibitors (dabrafenib and vemurafenib), human epidermal growth factor receptor inhibitors (lapatinib, gefitinib, erl
Autor:
Samarth Reddy, Sigrun Hallmeyer, Phillip J. DeChristopher, Nadim Mahmud, Supriya Perambakam, Linda R. Bressler, Rafael Nunez, Delores Mahmud, David Peace, Jeffrey A. Sosman
Publikováno v:
Cancer Immunology, Immunotherapy. 55:1033-1042
T cell immunotherapy of prostate cancer (CaP) offers the potential for less toxic, more effective outcomes. A clinical trial was conducted in 28 patients with locally advanced or metastatic CaP to determine whether an HLA-A2 binding epitope of prosta
Autor:
Robert E. Molokie, Donald Lavelle, Mabel Koshy, Linda R. Bressler, Nasrin Talischy, Louise Dorn, Joseph DeSimone
Publikováno v:
Blood. 99:3905-3908
We have previously demonstrated that 5-aza-2'-deoxycytidine (decitabine) augments fetal hemoglobin (HbF) levels in patients with sickle cell anemia (SS) who did not respond to hydroxyurea (HU). The present study was designed to determine the effect o
Publikováno v:
Cancer Chemotherapy and Pharmacology. 69:1113-1115
The benefit of six cycles of adjuvant temozolomide was documented in a randomized phase III (EORTC-NCIC CE.3) trial, and this therapy, following combined temozolomide and radiation, is the standard of care for patients with newly diagnosed glioblasto
Publikováno v:
Journal of Neuro-Oncology. 87:119-121
We quantify a three day tumor doubling time for small cell lung cancer metastatic to the brain in a case of a 61 yearold woman with a 30 pack-year smoking history. She was diagnosed with extensive stage small cell lung carcinoma with bone metastases
Publikováno v:
Anti-Cancer Drugs. 18:827-829
Cetuximab (Erbitux) is a recombinant, chimeric monoclonal antibody that binds with high affinity to the extracellular ligand-binding domain of human epidermal growth factor receptor. We report a case of repeated responses to cetuximab in a patient wi