Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Linda Plappert"'
Autor:
Sabrina Blumer, Petra Khan, Nataliia Artysh, Linda Plappert, Spasenija Savic, Lars Knudsen, Danny Jonigk, Mark P. Kuehnel, Antje Prasse, Katrin E. Hostettler
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Honeycomb cysts (HC) within the alveolar region are distinct histopathological features in the lungs of idiopathic pulmonary fibrosis (IPF) patients. HC are lined with a single-or stratified layer of basal cells (BC), or with a br
Externí odkaz:
https://doaj.org/article/853d69fcaa924208a376d6da546282e9
Autor:
Benedikt Jaeger, Jonas Christian Schupp, Linda Plappert, Oliver Terwolbeck, Nataliia Artysh, Gian Kayser, Peggy Engelhard, Taylor Sterling Adams, Robert Zweigerdt, Henning Kempf, Stefan Lienenklaus, Wiebke Garrels, Irina Nazarenko, Danny Jonigk, Malgorzata Wygrecka, Denise Klatt, Axel Schambach, Naftali Kaminski, Antje Prasse
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The functional role of airway basal cells has not been comprehensively studied in idiopathic pulmonary fibrosis (IPF). Here, the authors show that airway basal cells of IPF patients display a distinct phenotype, are profibrotic if transplanted to mic
Externí odkaz:
https://doaj.org/article/107b6a818628494fa216ab22d702c61d
Autor:
Benedikt, Jaeger, Jonas Christian, Schupp, Linda, Plappert, Oliver, Terwolbeck, Nataliia, Artysh, Gian, Kayser, Peggy, Engelhard, Taylor Sterling, Adams, Robert, Zweigerdt, Henning, Kempf, Stefan, Lienenklaus, Wiebke, Garrels, Irina, Nazarenko, Danny, Jonigk, Malgorzata, Wygrecka, Denise, Klatt, Axel, Schambach, Naftali, Kaminski, Antje, Prasse
Publikováno v:
Nature communications. 13(1)
Idiopathic pulmonary fibrosis (IPF) is a fatal disease with limited treatment options. In this study, we focus on the properties of airway basal cells (ABC) obtained from patients with IPF (IPF-ABC). Single cell RNA sequencing (scRNAseq) of bronchial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df8d6e051e40ece19b8910c517136a8e
https://pubmed.ncbi.nlm.nih.gov/36163190
https://pubmed.ncbi.nlm.nih.gov/36163190
Autor:
Malgorzata Wygrecka, Gian Kayser, Taylor Adams, Axel Schambach, Benedikt Jaeger, Oliver Terwolbeck, Robert Zweigerdt, Danny Jonigk, Naftali Kaminski, Stefan Lienenklaus, Wiebke Garrels, Antje Prasse, Henning Kempf, Denise Klatt, Peggy Engelhard, Jonas C. Schupp, Irina Nazarenko, Linda Plappert
Idiopathic pulmonary fibrosis (IPF) is a fatal disease with limited treatment options. In this study we focus on the profibrotic properties of airway basal cells (ABC) obtained from patients with IPF (IPF-ABC). Single cell RNA sequencing of bronchial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58339604003c517f95aa9db791c9b3d2
https://doi.org/10.1101/2020.09.04.283408
https://doi.org/10.1101/2020.09.04.283408
Autor:
Axel Schambach, Denise Klatt, Philippe Dänzer Barbosa, Benedikt Jäger, Antje Prasse, Stefan Lienenklaus, Heiko Golpon, Linda Plappert
Publikováno v:
Cellular signalling. 73
Overexpression of C-X-C chemokine receptor type 4 (CXCR4) has been shown in several cancers, including non-small cell lung cancer (NSCLC) and is linked to early metastasis and worse prognosis. The crosstalk between cancer cells and tumor stroma promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6264eb0262e137c0dcaebd27f843628
https://pubmed.ncbi.nlm.nih.gov/32428553
https://pubmed.ncbi.nlm.nih.gov/32428553
Autor:
Benedikt Jäger, Stefanie Reusz, Bruno Campiani, Jonas C. Schupp, Linda Plappert, Antje Prasse, Susanne Rittinghausen
Publikováno v:
Herbsttagung der Sektion Zellbiologie in der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V..
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1a250450398237bc3ba2a9f3f13bdae
https://doi.org/10.1055/s-0039-1678396
https://doi.org/10.1055/s-0039-1678396
Background: The widely used mouse bleomycin model does not resemble idiopathic pulmonary fibrosis (IPF) adequately. In particular, the spontaneous resolution of fibrotic lesions and the lack of honeycombing are major pitfalls. To confirm a role of ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418f45f3da5c6dd8723c0bdd7b8f2769
https://publica.fraunhofer.de/handle/publica/259302
https://publica.fraunhofer.de/handle/publica/259302
Autor:
Sabine Kasimir-Bauer, Corinna Keup, Hans-Christian Kolberg, Linda Plappert, Bahriye Aktas, Markus Sprenger-Haussels, Pawel Mach, Mitra Tewes, Rainer Kimmig, Siegfried Hauch
Publikováno v:
Cancer Research. 77:3777-3777
Background: Blood analytes, as liquid biopsies, are discussed to be surrogate markers for therapy stratification of metastatic breast cancer (MBC) patients. Repeated analysis is enabled by the minimal invasive nature of blood draw. Analysis of RNA en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b4a7c436684df1581cd4b7e9729d635
https://doi.org/10.1158/1538-7445.am2017-3777
https://doi.org/10.1158/1538-7445.am2017-3777
Autor:
Lorenzo Cohen, V. Valero, Ricardo H. Alvarez, Oliver Hoffmann, W.A. Woodward, JM Reuben, S Kasimir-Bauer, NT Ueno, R Kimmig, N Feniuk, Linda Plappert, Hui Gao, A-K Bittner
Publikováno v:
Cancer Research. 77:P1-01
Background: Triple negative breast cancer (TNBC) is known for its aggressive behavior and poor prognosis since treatment options are limited. Specific biomarkers are urgently needed to treat patients (pts) accordingly. In this regard, circulating tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47fca58b92d451d77507a76d2b334546
https://doi.org/10.1158/1538-7445.sabcs16-p1-01-19
https://doi.org/10.1158/1538-7445.sabcs16-p1-01-19
Autor:
Elisa Varriale, Linda Plappert, Enrico Cortesi, Paola Gazzaniga, Chiara Nicolazzo, Elena De Falco, Angela Gradilone, Cristina Raimondi, Giuseppe Giannini, Siegfried Hauch, Isotta Chimenti
Publikováno v:
Cancer biologytherapy. 15(5)
The hypothesis of the “liquid biopsy” using circulating tumor cells (CTCs) emerged as a minimally invasive alternative to traditional tissue biopsy to determine cancer therapy. Discordance for biomarkers expression between primary tumor tissue an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e8d794c485d543d49df319b57f29f9
https://pubmed.ncbi.nlm.nih.gov/24521660
https://pubmed.ncbi.nlm.nih.gov/24521660