Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Linda Masat"'
Autor:
Paul D. Larsen, Alexander Owyang, Elizabeth Pongo, Marina Roell, Mary Haak-Frendscho, Masahisa Handa, Linda Masat, Hassan Issafras, Kiran Ahluwalia, John Corbin, Arnold Horwitz
Publikováno v:
mAbs. 3:49-60
Interleukin-1β (IL-1β) is a potent mediator of inflammatory responses and plays a role in the differentiation of a number of lymphoid cells. In several inflammatory and autoimmune diseases, serum levels of IL-1β are elevated and correlate with dis
Autor:
Paul D. Larsen, Amita Patel, Susan J. Babuka, Jeremy Kam-Kuen Ma, Ssucheng J. Hsu, Robert J. Bauer, Marina Roell, Linda Masat, Mary Haak-Frendscho, David J. Bohmann, Rhonda K. Hansen, Mark L. White
Publikováno v:
Biochemical Pharmacology. 76:340-352
The peptide hormone gastrin is a key factor in regulation of gastric acid secretion. It has also been implicated in the development or maintenance of various types of cancer, such as pancreatic and stomach carcinoma. Inhibition of gastrin activity ha
Autor:
H. Khoshnevisan, R. Jessberger, Brian G. Herndier, Randall Armstrong, J. Caldwell, D. Ferrick, Matthias Wabl, Linda Masat
Publikováno v:
Proceedings of the National Academy of Sciences. 97:2180-2184
SWAP-70 is a component of an enzyme complex that recombines Ig switch regions in vitro . We report here the cloning of the human cDNA and its B lymphocyte-specific expression. Although its sequence contains three nuclear localization signals, in smal
Autor:
R. A. Liddell, Beverly A. Mock, Linda Masat, Matthias Wabl, W. L. Kuo, Herbert C. Morse, Rolf Jessberger
Publikováno v:
Scopus-Elsevier
The protein SWAP-70 was isolated as part of a DNA recombination complex in B lymphocytes, where it is predominantly expressed. In resting B cells, SWAP-70 is found in the cytoplasm; upon B-cell activation, it is transported both into the nucleus and
Autor:
Brigitte Riwar, Rolf Jessberger, Giorgio Cattoretti, Tilman Borggrefe, Linda Masat, Matthias Wabl
Publikováno v:
European Journal of Immunology. 29:1812-1822
SWAP-70 is part of a protein complex that catalyzes cell-free DNA recombination between immunoglobulin heavy chain gene switch region substrates. This report studies the expression pattern of SWAP-70 in mouse tissues, sorted cells, and cultured prima
Publikováno v:
CIÊNCIAVITAE
Scopus-Elsevier
Scopus-Elsevier
As a model for studying the generation of antibody diversity, a gene-targeted mouse was produced that is hemizygous for a rearranged V(D)J segment at the immunoglobulin (Ig) heavy chain locus, the other allele being nonfunctional. The mouse also has
Publikováno v:
Proceedings of the National Academy of Sciences. 91:893-896
The monoclonal antibody NEMO is directed against a molecule expressed by human cells of the melanocytic lineage. Although obtained by conventional immunization and fusion procedures, NEMO consists solely of kappa light chain. SDS/PAGE analysis indica
Autor:
Lin Esposito, Mary Haak-Frendscho, Marina Roell, Paul D. Larsen, John Corbin, Seema Kantak, Alexander Owyang, Elizabeth Pongo, Nathalie Dubois-Stringfellow, David G. Alleva, Linda Masat, Arnold Horwitz, Kiran Ahluwalia, Sandra Vanegas
Publikováno v:
Clinical Immunology. 127:S98-S99
Autor:
Linda Masat, Matthias Wabl
Publikováno v:
Biological Chemistry. 378
The Na,K-ATPase, or sodium pump, a ubiquitous transmembrane enzyme in higher eukaryotes, consists of an alpha and a beta subunit. Here we investigate the expression pattern of the two beta isotypes in mouse B cell lines. Neither primary cells nor cel
Publikováno v:
European journal of immunology. 26(11)
The Na,K-ATPase, or sodium pump, is responsible for maintaining cellular volume and is involved in receptor-mediated endocytosis; it is a ubiquitous transmembrane enzyme in higher eukaryotes and consists of an alpha and a beta subunit. In the mouse,