Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Linda Manta"'
Autor:
Wenwen Wang, Thomas Stiehl, Simon Raffel, Van T. Hoang, Isabel Hoffmann, Laura Poisa-Beiro, Borhan R. Saeed, Rachel Blume, Linda Manta, Volker Eckstein, Tilmann Bochtler, Patrick Wuchter, Marieke Essers, Anna Jauch, Andreas Trumpp, Anna Marciniak-Czochra, Anthony D. Ho, Christoph Lutz
Publikováno v:
Haematologica, Vol 102, Iss 9 (2017)
In patients with acute myeloid leukemia and low percentages of aldehyde-dehydrogenase-positive cells, non-leukemic hematopoietic stem cells can be separated from leukemic cells. By relating hematopoietic stem cell frequencies to outcome we detected p
Externí odkaz:
https://doaj.org/article/8b5d4d2146944497bcdbb88a2061a61c
Autor:
Anthony D. Ho, Wolfgang Huber, Anna Jauch, Volker Eckstein, Andreas Trumpp, Linda Manta, Borhan R. Saeed, Wenwen Wang, Paul Theodor Pyl, Simon Raffel, Christoph Lutz, Eike C. Buss
Publikováno v:
International Journal of Cancer. 148:2825-2838
To acquire a better understanding of clonal evolution of acute myeloid leukemia (AML) and to identify the clone(s) responsible for disease recurrence, we have comparatively studied leukemia-specific mutations by whole-exome-sequencing (WES) of both t
Autor:
Olga Ermakova, Christoph Lutz, Andreas Trumpp, Vladimir Benes, Simon Raffel, Borhan R. Saeed, Volker Eckstein, Anthony D. Ho, Eugen Rempel, Wenwen Wang, Rachel Blume, Linda Manta
Publikováno v:
Leukemia & Lymphoma. 59:2201-2210
Enrichment of leukemic blasts with a stem cell phenotype correlates with poor survival in acute myeloid leukemia (AML). In this context, measurement of the stem cell marker aldehyde-dehydrogenase (ALDH) activity can distinguish poor prognosis cases w
Autor:
Linda Manta, Christoph Lutz, Haiju He, Patrick Wuchter, Wenwen Wang, Volker Eckstein, Tilmann Bochtler, Anthony D. Ho
Publikováno v:
European Journal of Haematology. 99:392-398
Objective Persistence of leukemic cells after induction therapy has been shown to correlate with poor survival in acute myeloid leukemia (AML). In this study we tested if human mesenchymal stromal cells (hMSC) have protective effects on leukemic cell
Autor:
Isabel Hoffmann, Van T. Hoang, Rachel Blume, Anna Marciniak-Czochra, Anna Jauch, Andreas Trumpp, Wenwen Wang, Christoph Lutz, Laura Poisa-Beiro, Borhan R. Saeed, Linda Manta, Tilmann Bochtler, Patrick Wuchter, Simon Raffel, Volker Eckstein, Thomas Stiehl, Anthony D. Ho, Marieke A.G. Essers
Publikováno v:
Haematologica
In patients with acute myeloid leukemia and low percentages of aldehyde-dehydrogenase-positive cells, non-leukemic hematopoietic stem cells can be separated from leukemic cells. By relating hematopoietic stem cell frequencies to outcome we detected p
Autor:
Ludwig Lausser, Christoph Paone, Linda Manta, Steffen Just, Cora Wiesner, Hans A. Kestler, Rolf Schröder, Wolfgang Rottbauer, Christoph S. Clemen, Marco Sandri, Jochen Kustermann, Monika Kustermann, Ludwig Eichinger
Publikováno v:
Autophagy. 14(11)
VCP/p97 (valosin containing protein) is a key regulator of cellular proteostasis. It orchestrates protein turnover and quality control in vivo, processes fundamental for proper cell function. In humans, mutations in VCP lead to severe myo- and neuro-
Autor:
Dieter O. Fürst, Linda Manta, Joachim Schessl, Rolf Schröder, Peter F.M. van der Ven, Benedikt Schoser, Ludwig Eichinger, Sofia Hirth, Steffen Just, Mirjam Keßler, Sören Westphal, John B. Bührdel, Christoph S. Clemen, Monika Forster, Gerhard Wiche, Wolfgang Rottbauer
Publikováno v:
Biochemical and Biophysical Research Communications. 461(2):217-223
Myofibrillar myopathies (MFM) are progressive diseases of human heart and skeletal muscle with a severe impact on life quality and expectancy of affected patients. Although recently several disease genes for myofibrillar myopathies could be identifie