Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Linda M. Schirtzinger"'
Autor:
David O. Calligaro, Marnie A. Higgins, Linda M. Schirtzinger, Timothy P. Ryan, Hong Gao, Elizabeth Galbreath, George H. Searfoss, Patrick C. May, Brian R. Berridge, William H. Jordan
Publikováno v:
Journal of Biological Chemistry. 278:46107-46116
Functional gamma-secretase inhibitors (FGSIs) can block the cleavage of several transmembrane proteins including amyloid precursor protein (APP), and the cell fate regulator Notch-1. FGSIs, by inhibiting APP processing, block the generation of amyloi
Autor:
Philip W. Iversen, Yun-Fei Chen, Kristan A. Keyes, Beverly A. Teicher, Michael Sherman, Darryl Ballard, Elizabeth Galbreath, Larry Mann, Linda M. Schirtzinger
Publikováno v:
Cancer chemotherapy and pharmacology. 53(2)
Angiogenesis plays an important role in tumor growth. Angiogenic growth factors may be useful as biomarkers of antiangiogenic activity since their plasma concentrations correlate with the efficacy of treatments directed toward angiogenic targets. SW2