Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Linda M. Pullan"'
Autor:
Hitzemann, Robert
Publikováno v:
The Quarterly Review of Biology, 1996 Dec 01. 71(4), 601-603.
Externí odkaz:
https://www.jstor.org/stable/3037100
Autor:
Michael Williams
Publikováno v:
Drug Development Research. 37:61-61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6266da968b787502e248c7dd0c12c6c
https://doi.org/10.1002/ddr.430370102
https://doi.org/10.1002/ddr.430370102
Autor:
Ferkany, J. W.
Publikováno v:
Journal of Medicinal Chemistry; December 20, 1996, Vol. 39 Issue: 26 p5289-5290, 2p
Autor:
David C. U'Prichard, Linda M. Pullan
Publikováno v:
Research-Technology Management. 40:35-39
Today's drug discovery research organization must consider what the healthcare business will look like in 2015. David C. U'Prichard and Linda M. Pullan OVERVIEW: Increased cost pressures, more informative and expensive clinical data, and many competi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fa751b42d22ea6ca3e77a1398f05958
https://doi.org/10.1080/08956308.1997.11671168
https://doi.org/10.1080/08956308.1997.11671168
Publikováno v:
Journal of Neurochemistry. 59:2087-2093
Neomycin appears as a full agonist and spermidine as a partial agonist at the site where polyamines enhance 1-[1-(2-thienyl)cyclohexyl][3H]piperidine ([3H]TCP) binding on the N-methyl-D-aspartate (NMDA) receptor. Other aminoglycosides also enhance [3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb45a77a8dff39e2e8ab9858e7f3959d
https://doi.org/10.1111/j.1471-4159.1992.tb10099.x
https://doi.org/10.1111/j.1471-4159.1992.tb10099.x
Autor:
Christopher H. Sotak, Marc Fisher, Andreas Bergmann, Thomas M. Bare, James E. Formato, Richard A.D. Carano, Linda M. Pullan, Turgut Tatlisumak, Kentaro Takano
Publikováno v:
Stroke. 28:1255-1263
Background and Purpose The glycine site on the N -methyl- d -aspartate (NMDA) receptor complex offers a therapeutic target for acute focal ischemia, potentially devoid of most side effects associated with competitive and noncompetitive NMDA antagonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72d7ff894d41ac82de18516f94bc2b1
https://doi.org/10.1161/01.str.28.6.1255
https://doi.org/10.1161/01.str.28.6.1255
Autor:
Linda M. Pullan, Jeffrey M. Goldstein, James R. Damewood, Paul F. Jackson, Jeffrey A. McKinney, Timothy Davenport, Gregory G. Harris, Laura Garcia, Margaret G. Melville, Marc J. Chapdelaine
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:3097-3100
A series of 4-arylbenz[b]azepine analogs were prepared and shown to act as antagonists at the strychnine-insensitive glycine receptor. The heteroaryl substituted benz[b]azepine derivative 11 also showed excellent in vivo activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59678d848e45b17ab696e2481e0e42ae
https://doi.org/10.1016/0960-894x(95)00544-0
https://doi.org/10.1016/0960-894x(95)00544-0
Autor:
Linda M. Pullan, Clyde W. Draper, Jitendra Patel, Thomas M. Bare, Jitendra B. Patel, Charles D. McLaren
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:55-60
A series of novel spiroisoindolines was designed and synthesized as potential noncompetitive NMDA antagonists. Affinities of these compounds for the noncompetitive NMDA binding site were determined using [3H]TCP and found to possess IC50s ranging fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8986e12ad0581c7dce8e401b8ade4e5
https://doi.org/10.1016/s0960-894x(00)80091-8
https://doi.org/10.1016/s0960-894x(00)80091-8
Autor:
Timothy Davenport, Paul F. Jackson, Gregory G. Harris, Laura Garcia, Jeffrey A. McKinney, James R. Damewood, Linda M. Pullan, Marc J. Chapdelaine, Margaret G. Melville, Jeffrey M. Goldstein
Publikováno v:
ChemInform. 27
A series of 4-arylbenz[b]azepine analogs were prepared and shown to act as antagonists at the strychnine-insensitive glycine receptor. The heteroaryl substituted benz[b]azepine derivative 11 also showed excellent in vivo activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eca26a5b5c511165119a61f05f46422a
https://doi.org/10.1002/chin.199615188
https://doi.org/10.1002/chin.199615188
Publikováno v:
European Journal of Pharmacology: Molecular Pharmacology. 208:25-29
HA-966 (1-hydroxy-3-amino-pyrrolid-2-one), an antagonist at the strychine-insensitive glycine site on the N-methyl-D-aspartate (NMDA) receptor complex, only partially inhibits the binding of noncompetitive antagonists to the NMDA receptor but enhance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b280b5beae5a45629400866f6ba981cc
https://doi.org/10.1016/0922-4106(91)90047-l
https://doi.org/10.1016/0922-4106(91)90047-l