Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Linda M. O'Keeffe"'
Autor:
Kate N. O'Neill, Joshua A. Bell, George Davey Smith, Abigail Fraser, Laura D. Howe, Patricia M. Kearney, Oliver Robinson, Kate Tilling, Peter Willeit, Linda M. O'Keeffe
Publikováno v:
EBioMedicine, Vol 98, Iss , Pp 104884- (2023)
Summary: Background: Socioeconomic inequalities in cardiovascular disease risk begin early in life and are more pronounced in females than males later in life. Causal atherogenic traits explaining this are not well understood. We explored sex-specifi
Externí odkaz:
https://doaj.org/article/1dd9abd53ba342e580da35b0fecac055
Autor:
Anna Delahunt, Marie C. Conway, Eileen C. O’Brien, Aisling A. Geraghty, Linda M. O’Keeffe, Sharleen L. O’Reilly, Ciara M. McDonnell, Patricia M. Kearney, John Mehegan, Fionnuala M. McAuliffe
Publikováno v:
BMC Pediatrics, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Individual differences in children eating behaviours have been linked with childhood overweight and obesity. The determinants of childhood eating behaviours are influenced by a complex combination of hereditary and ecological fact
Externí odkaz:
https://doaj.org/article/ebe405aa2d074e3c992244d7b26aedd8
Autor:
Kate N. O’Neill, Emily Aubrey, Laura D. Howe, Evie Stergiakouli, Santiago Rodriguez, Patricia M. Kearney, Linda M. O’Keeffe
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Background Mitochondria are organelles responsible for converting glucose into energy. Mitochondrial DNA is exclusively maternally inherited. The role of mitochondrial DNA haplogroups in the aetiology of cardiometabolic disease risk is not well under
Externí odkaz:
https://doaj.org/article/e174a95b947d4375833cdd286630d4cc
Autor:
Joshua A. Bell, Tom G. Richardson, Qin Wang, Eleanor Sanderson, Tom Palmer, Venexia Walker, Linda M. O'Keeffe, Nicholas J. Timpson, Anna Cichonska, Heli Julkunen, Peter Würtz, Michael V. Holmes, George Davey Smith
Publikováno v:
The Lancet Regional Health. Europe, Vol 21, Iss , Pp 100457- (2022)
Summary: Background: The direct effects of general adiposity (body mass index (BMI)) and central adiposity (waist-to-hip-ratio (WHR)) on circulating lipoproteins, lipids, and metabolites are unknown. Methods: We used new metabolic data from UK Bioban
Externí odkaz:
https://doaj.org/article/0109e225c9814daebc7a73d4d765b914
Autor:
Gillian M. Maher, Lisa Ryan, Fergus P. McCarthy, Alun Hughes, Chloe Park, Abigail Fraser, Laura D. Howe, Patricia M. Kearney, Linda M. O’Keeffe
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-8 (2021)
Abstract Background Whether earlier onset of puberty is associated with higher cardiovascular risk in early adulthood is not well understood. Our objective was to examine the association between puberty timing and markers of cardiovascular structure
Externí odkaz:
https://doaj.org/article/cba709bca72449689a63b3b822813cc5
Sex differences in systemic metabolites at four life stages: cohort study with repeated metabolomics
Autor:
Joshua A. Bell, Diana L. Santos Ferreira, Abigail Fraser, Ana Luiza G. Soares, Laura D. Howe, Deborah A. Lawlor, David Carslake, George Davey Smith, Linda M. O’Keeffe
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Males experience higher rates of coronary heart disease (CHD) than females, but the circulating traits underpinning this difference are poorly understood. We examined sex differences in systemic metabolites measured at four life s
Externí odkaz:
https://doaj.org/article/f7c6483a425b4b8ea8d7f5e8669b6579
Autor:
Marion Murphy, Sheena McHugh, Linda M. O’Keeffe, Richard A. Greene, Paul Corcoran, Patricia M. Kearney
Publikováno v:
BMC Pregnancy and Childbirth, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Maternal behaviours during pregnancy have short- and long-term consequences for maternal and infant health. Pregnancy is an ideal opportunity to encourage positive behaviour change. Despite this, limited information exists about t
Externí odkaz:
https://doaj.org/article/c4a4d12f3c00441e9a6f0e5fa7034b7d
Autor:
Lena Tschiderer, Lisa Seekircher, Setor K. Kunutsor, Sanne A. E. Peters, Linda M. O’Keeffe, Peter Willeit
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 2 (2022)
Background Breastfeeding has been robustly linked to reduced maternal risk of breast cancer, ovarian cancer, and type 2 diabetes. We herein systematically reviewed the published evidence on the association of breastfeeding with maternal risk of cardi
Externí odkaz:
https://doaj.org/article/cf23549786164065ab1a64f33790d127
Autor:
Jasmine N. Khouja, Andrew J. Simpkin, Linda M. O’Keeffe, Kaitlin H. Wade, Lotte C. Houtepen, Caroline L. Relton, Matthew Suderman, Laura D. Howe
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-9 (2018)
Abstract Background Gestational age at delivery is associated with health and social outcomes. Recently, cord blood DNA methylation data has been used to predict gestational age. The discrepancy between gestational age predicted from DNA methylation
Externí odkaz:
https://doaj.org/article/0e271affad7d41c79688e97f0dfa998f
Autor:
Linda M. O’Keeffe, Andrew J. Simpkin, Kate Tilling, Emma L. Anderson, Alun D. Hughes, Debbie A. Lawlor, Abigail Fraser, Laura D. Howe
Publikováno v:
Data in Brief, Vol 23, Iss , Pp - (2019)
Cardiometabolic disease risk begins in early life and tracks through the life course. As described in “Sex-specific trajectories of measures of cardiovascular health during childhood and adolescence: a prospective cohort study” (O’Keeffe et al.
Externí odkaz:
https://doaj.org/article/14baa4ac237b431ba9c7eec0886bcc1e