Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Linda M. Boxer"'
Autor:
Linda M. Boxer, Upinder Singh
Publikováno v:
The Clinician Educator Guidebook ISBN: 9783319279794
Roberts Academic Medicine Handbook ISBN: 9783030319564
The Academic Medicine Handbook ISBN: 9781461456926
The Associate Professor Guidebook ISBN: 9783319280004
Roberts Academic Medicine Handbook ISBN: 9783030319564
The Academic Medicine Handbook ISBN: 9781461456926
The Associate Professor Guidebook ISBN: 9783319280004
A career in academic medicine provides intellectual freedom and is very rewarding. In searching for an academic position, it is critical to make certain that one’s goals match those of the department and institution. Be clear on the expectations fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae4b0551bcc9e8d330544726ae25710
https://doi.org/10.1007/978-3-319-27980-0_2
https://doi.org/10.1007/978-3-319-27980-0_2
Autor:
Hong Duan, Linda M. Boxer, Jinghong Wang, Sara A. Michie, Hong-Bing Xiang, Emily J. Noonan, Lawrence K. Ma
Publikováno v:
Leukemia
Human follicular B-cell lymphoma is associated with the t(14;18) chromosomal translocation that juxtaposes the Bcl2 proto-oncogene with the immunoglobulin heavy chain (Igh) locus, resulting in the deregulated expression of Bcl2. Our previous studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe5ec2830c438f5ab47cceb0c0afcdd
https://doi.org/10.1038/leu.2011.115
https://doi.org/10.1038/leu.2011.115
Publikováno v:
ChemBioChem. 8:332-340
Various proteins involved in transcriptional regulation possess highly selective DNA-binding domains, known as zinc fingers. However, little is known about small-molecule zinc(II) complexes in the regulation of gene expression and programmed cell dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465638c0bda6104811a641861ff12319
https://doi.org/10.1002/cbic.200600299
https://doi.org/10.1002/cbic.200600299
Autor:
H. Phillip Koeffler, Linda M. Boxer, Dong Hong Cai, Jeanne Kowalski, Adrian F. Gombart, Huaitian Liu, Caroline A. Heckman, Amanda L. Blackford, Ido Paz-Priel, Alan D. Friedman, Dehua Wang
Publikováno v:
Molecular Cancer Research. 3:585-596
The CEBPA gene is mutated in 10% of acute myeloid leukemia (AML) cases. We find that CEBPA and Bcl-2 RNA levels correlate highly in low-risk human AMLs, suggesting that inhibition of apoptosis via induction of bcl-2 by CCAAT/enhancer binding protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c972abe1499f99e1b7dcb9a8313dd13b
https://doi.org/10.1158/1541-7786.mcr-05-0111
https://doi.org/10.1158/1541-7786.mcr-05-0111
Publikováno v:
Oncogene. 25:888-898
Oct-1 and Oct-2 are members of the POU homeodomain family of transcriptional regulators and are critical for normal embryonic development. Gene-targeting studies showed that Oct-1 and Oct-2 are largely dispensable for B-cell development and immunoglo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883196954573e404b8b12421ea05978e
https://doi.org/10.1038/sj.onc.1209127
https://doi.org/10.1038/sj.onc.1209127
Autor:
Linda M. Boxer, Jinghong Wang
Publikováno v:
Journal of Biological Chemistry. 280:12766-12773
Burkitt's lymphoma is invariably associated with chromosomal translocations that juxtapose the c-myc proto-oncogene with regulatory elements of the immunoglobulin heavy (IgH) or light chain loci resulting in the deregulation of c-myc expression. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9b604134e843b825d223d118ab9f71
https://doi.org/10.1074/jbc.m412446200
https://doi.org/10.1074/jbc.m412446200
Publikováno v:
Molecular and Cellular Biology. 25:1608-1619
Histone deacetylase (HDAC) inhibitors are promising antitumor agents, but they have not been extensively explored in B-cell lymphomas. Many of these lymphomas have the t(14;18) translocation, which results in increased bcl-2 expression and resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40baa337fa51e80093c4459dffd2788d
https://doi.org/10.1128/mcb.25.5.1608-1619.2005
https://doi.org/10.1128/mcb.25.5.1608-1619.2005
Publikováno v:
Cancer Research. 65:291-299
To investigate the effect of l-asparaginase on acute lymphoblastic leukemia (ALL), we used cDNA microarrays to obtain a genome-wide view of gene expression both at baseline and after in vitro exposure to l-asparaginase in cell lines and pediatric ALL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::345a0ad1549ad34328482da43c8cf341
https://doi.org/10.1158/0008-5472.291.65.1
https://doi.org/10.1158/0008-5472.291.65.1
Publikováno v:
Journal of Neurochemistry. 89:951-961
Our previous results suggested that the transcription factor CREB mediates the actions of neuroligands and growth factor signals that coupled to different signaling pathways may play different roles along oligodendrocyte (OLG) development. We showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44dce607145951868d71cba762974dbf
https://doi.org/10.1111/j.1471-4159.2004.02365.x
https://doi.org/10.1111/j.1471-4159.2004.02365.x
Autor:
Jochen Harbott, Martin Stanulla, Susanne Viehmann, Martin Schrappe, Bernard M. Fine, Linda M. Boxer, Minh Ho
Publikováno v:
Blood. 103:1043-1049
We obtained a global view of gene expression in both cell lines and pediatric acute lymphoblastic leukemia (ALL) samples that harbor one of several selected chromosomal abnormalities. When the cell lines were studied alone, we found that these chromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d0a3e78c2c685f11627236a57e96a5
https://doi.org/10.1182/blood-2003-05-1518
https://doi.org/10.1182/blood-2003-05-1518