Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Linda M Sircy"'
Autor:
Aarthi Subramani, Prianca Griggs, Niah Frantzen, James Mendez, Jamila Tucker, Jada Murriel, Linda M Sircy, Grace E Millican, Erin E McClelland, Rebecca L Seipelt-Thiemann, David E Nelson
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0233818 (2020)
Macrophages serve as a first line of defense against infection with the facultative intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability of these innate phagocytic cells to destroy ingested Cn is strongly influenced by polarizat
Externí odkaz:
https://doaj.org/article/ae07982466ca4e43b3029e782d2c1994
Autor:
Nguyen X. Nguyen, Andrew W. Richens, Linda M. Sircy, Denise E. Allard, Elizabeth M. Kolawole, Brian D. Evavold, Maria Bettini, J. Scott Hale
Publikováno v:
The Journal of Immunology. 210:916-925
The activation-induced marker (AIM) assay is a cytokine-independent technique to identify Ag-specific T cells based on the upregulated expression of activation markers after Ag restimulation. The method offers an alternative to intracellular cytokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3876a29ee0101c25ecc24eded0dc3c01
https://doi.org/10.4049/jimmunol.2200638
https://doi.org/10.4049/jimmunol.2200638
Autor:
Andrew Baessler, Camille L. Novis, Zuolian Shen, Jelena Perovanovic, Mark Wadsworth, Kendall A. Thiede, Linda M. Sircy, Malia Harrison-Chau, Nguyen X. Nguyen, Katherine E. Varley, Dean Tantin, J. Scott Hale
Publikováno v:
Science advances. 8(24)
In response to various types of infection, naïve CD4 + T cells differentiate into diverse helper T cell subsets; however, the epigenetic programs that regulate differentiation in response to viral infection remain poorly understood. Demethylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d842caec5831a699864bc747391b05
https://pubmed.ncbi.nlm.nih.gov/35704571
https://pubmed.ncbi.nlm.nih.gov/35704571
Autor:
J. Scott Hale, Camille L. Novis, Malia Harrison-Chau, Jacklyn Nguyen, Linda M. Sircy, Andrew Baessler
Publikováno v:
J Immunol
Acute viral infection generates lineage-committed Th1 and T follicular helper (Tfh) memory cells that recall their lineage-specific functions following secondary challenge with virus. However, the lineage commitment of effector and memory Th cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd035a79429239db83724179857b01d4
https://europepmc.org/articles/PMC8387422/
https://europepmc.org/articles/PMC8387422/
Autor:
J. Scott Hale, Andrew Baessler, Camille L Novis, Zuolian Shen, Jelena Perovanovic, Mark Wadsworth, Linda M Sircy, Malia Harrison-Chau, Katherine E Varley, Dean R Tantin
Publikováno v:
The Journal of Immunology. 208:112.24-112.24
The differentiation of CD4+ T cell subsets in response to infection has been studied extensively, however the epigenetic programs that regulate these processes remain poorly understood. Active demethylation by tet methylcytosine dioxygenases of CpG d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c19226231d1815f91f206a0eebcb0f49
https://doi.org/10.4049/jimmunol.208.supp.112.24
https://doi.org/10.4049/jimmunol.208.supp.112.24
Autor:
Prianca Griggs, Jamila Tucker, Grace E. Millican, Aarthi Subramani, Erin E. McClelland, James Mendez, Jada Murriel, David E. Nelson, Niah Frantzen, Linda M. Sircy, Rebecca L. Seipelt-Thiemann
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 8, p e0233818 (2020)
PLoS ONE, Vol 15, Iss 8, p e0233818 (2020)
Macrophages serve as a first line of defense against infection with the facultative intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability of these innate phagocytic cells to destroy ingested Cn is strongly influenced by polarizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b73b4f96eefa02a27b8629e88fbeff85
http://europepmc.org/articles/PMC7454990
http://europepmc.org/articles/PMC7454990
Autor:
James Mendez, Erin E. McClelland, Jada Murriel, Prianca Griggs, Jamila Tucker, Rebecca L. Seipelt-Thiemann, David E. Nelson, Niah Frantzen, Aarthi Subramani, Linda M. Sircy
Macrophages serve as a first line of defense against infection with the facultative intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability of these innate phagocytic cells to destroy ingested Cn is strongly influenced by polarizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5959ac4b8c23f3f117925a2ba0e72918
https://doi.org/10.1101/2020.05.14.095752
https://doi.org/10.1101/2020.05.14.095752
Autor:
Linda M Sircy, Malia Harrison-Chau, Camille Novis, Andrew Baessler, Jacklyn Nguyen, J. Scott Hale
Publikováno v:
The Journal of Immunology. 206:24.16-24.16
Acute viral infection generates lineage-committed T helper 1 (Th1) and T follicular helper (Tfh) memory cells that recall their lineage-specific functions following secondary challenge with virus. However, the lineage commitment of effector and memor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb85dbdc084621e117daf1a152e9109e
https://doi.org/10.4049/jimmunol.206.supp.24.16
https://doi.org/10.4049/jimmunol.206.supp.24.16
Autor:
Erin E. McClelland, Wandi Ding, David E. Nelson, James B. Hayes, Linda M. Sircy, Rachel Leander, Lauren E. Heusinkveld
Publikováno v:
Journal of Biological Chemistry. 291:15614-15627
Cryptococcus neoformans (Cn) is a common facultative intracellular pathogen that can cause life-threatening fungal meningitis in immunocompromised individuals. Shortly after infection, Cn is detectable as both extra- and intracellular yeast particles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44eb9407c3382f1cfc989376699e3fc4
https://doi.org/10.1074/jbc.m116.738187
https://doi.org/10.1074/jbc.m116.738187
Autor:
Kirsten D. Cunningham, Hoyin Lai, Serenah E Smith, David E. Nelson, Linda M. Sircy, Tiffany E Guess, Erin E. McClelland
Publikováno v:
Journal of Visualized Experiments.
The polysaccharide capsule of Cryptococcus neoformans is the primary virulence factor and one of the most commonly studied aspects of this pathogenic yeast. Capsule size can vary widely between strains, has the ability to grow rapidly when introduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e6cb84aefd30b21e949775cf9ddeaaa
https://doi.org/10.3791/57171
https://doi.org/10.3791/57171