Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Linda Møllersen"'
Publikováno v:
PLoS Genetics, Vol 6, Iss 12, p e1001242 (2010)
Huntington's disease (HD) is one of several neurodegenerative disorders caused by expansion of CAG repeats in a coding gene. Somatic CAG expansion rates in HD vary between organs, and the greatest instability is observed in the brain, correlating wit
Externí odkaz:
https://doaj.org/article/3b73c7df450645bb8982c95a40b34612
Autor:
Arne Klungland, Ingunn Holm, Olve Moldestad, Linda Møllersen, Lars Retterstøl, Linda Tveterås, Alexander D. Rowe, Anja Bjølgerud
Publikováno v:
PLoS Currents
Background: Huntington’s disease (HD) is a progressive neurodegenerative disorder caused by CAG repeat expansions in the HTT gene. Somatic repeat expansion in the R6/1 mouse model of HD depends on mismatch repair and is worsened by base excision re
Autor:
Per Selnes, Tormod Fladby, Dorna Misaghian, Meryl S. Lillenes, Vidar Stenset, Linda Møllersen, Alberto Rábano, Mari Støen, Tahira Riaz, Clara-Cecilie Günther, Ying Esbensen, Tone Tønjum
Publikováno v:
Molecular Brain
Background Alzheimer’s disease (AD) is a progressive, multifactorial neurodegenerative disorder that is the main cause of dementia globally. AD is associated with increased oxidative stress, resulting from imbalance in production and clearance of r
Autor:
Alexander D. Rowe, Linda Møllersen, Jennifer L. Illuzzi, Anja Bjølgerud, Gunn A. Hildrestrand, Magnar Bjørås, Arne Klungland, Katharina J. Gerhold, Linda Tveterås, David M. Wilson
Publikováno v:
Human Molecular Genetics
Huntington's disease (HD) is a progressive neurodegenerative disorder caused by trinucleotide repeat (TNR) expansions. We show here that somatic TNR expansions are significantly reduced in several organs of R6/1 mice lacking exon 2 of Nei-like 1 (Nei
Autor:
Jan Erik Paulsen, Inger-Lise Steffensen, Linda Møllersen, Åshild Kristine Andreassen, Rose Vikse, Arne Mikalsen, Jan Alexander
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 557:29-40
The heterocyclic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induces intestinal tumours in C57BL/6J-multiple intestinal neoplasia (Min)/+ mice. The main mechanism for PhIP-induced tumour induction in Min/+ mice is loss of the wild-ty
Publikováno v:
Anticancer research. 24(5A)
C57BL/6J Min/+ mice, which carry a nonsense mutation in Apc, were injected twice neonatally with 5 mg azoxymethane (AOM) /kg body weight. AOM treatment in comparison with untreated Min mice increased the incidence and number of colonic tumours from 6
Autor:
Linda Møllersen, Jan Erik Paulsen, Hege Benedikte Ølstørn, Helle Katrine Knutsen, Jan Alexander
Publikováno v:
Carcinogenesis; 1/1/2004, Vol. 25 Issue 1, p149-153, 5p