Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Linda Lubbers-Aalders"'
Autor:
Edo Vellenga, Robin Groen, Huipin Yuan, Jennifer Jaques, Jan Jacob Schuringa, J. D. de Bruijn, Anton C. M. Martens, Pallavi Sontakke, Linda Lubbers-Aalders, Annet Z. Brouwers-Vos, Marco Carretta
Publikováno v:
Leukemia, 30(10), 2064-2073. Nature Publishing Group
Sontakke, P, Carretta, M, Jaques, J, Brouwers-Vos, A Z, Lubbers-Aalders, L, Yuan, H, de Bruijn, J D, Martens, A C M, Vellenga, E, Groen, R W J & Schuringa, J J 2016, ' Modeling BCR-ABL and MLL-AF9 leukemia in a human bone marrow-like scaffold-based xenograft model ', Leukemia, vol. 30, no. 10, pp. 2064-2073 . https://doi.org/10.1038/leu.2016.108
Sontakke, P, Carretta, M, Jaques, J, Brouwers-Vos, A Z, Lubbers-Aalders, L, Yuan, H, de Bruijn, J D, Martens, A C M, Vellenga, E, Groen, R W J & Schuringa, J J 2016, ' Modeling BCR-ABL and MLL-AF9 leukemia in a human bone marrow-like scaffold-based xenograft model ', Leukemia, vol. 30, no. 10, pp. 2064-2073 . https://doi.org/10.1038/leu.2016.108
Although NOD-SCID IL2R gamma(-/-) (NSG) xenograft mice are currently the most frequently used model to study human leukemia in vivo, the absence of a human niche severely hampers faithful recapitulation of the disease. We used NSG mice in which ceram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0c8bd6c792f2d84c9033e9600b9ed2
https://doi.org/10.1038/leu.2016.108
https://doi.org/10.1038/leu.2016.108
Autor:
Anton C. M. Martens, Gert J. Ossenkoppele, Willy A. Noort, Jan Jacob Schuringa, Jenny Jaques, Antonella Antonelli, Andries C. Bloem, Annet Z. Brouwers-Vos, Regina de Jong-Korlaar, Joost D. de Bruijn, Jeroen F. van Velzen, Edo Vellenga, Linda Lubbers-Aalders, Huipin Yuan, Richard W.J. Groen, Bauke de Boer
Publikováno v:
Blood, 128(25), 2949-2959. AMER SOC HEMATOLOGY
Blood, 128(25), 2949-2959. American Society of Hematology
Antonelli, A, Noort, W A, Jaques, J, de Boer, B, de Jong-Korlaar, R, Brouwers-Vos, A Z, Lubbers-Aalders, L, van Velzen, J F, Bloem, A C, Yuan, H, de Bruijn, J D, Ossenkoppele, G J, Martens, A C M, Vellenga, E, Groen, R W J & Schuringa, J J 2016, ' Establishing human leukemia xenograft mouse models by implanting human bone marrow-like scaffold-based niches ', Blood, vol. 128, no. 25, pp. 2949-2959 . https://doi.org/10.1182/blood-2016-05-719021, https://doi.org/10.1182/blood-2016-05719021
Blood, 128(25), 2949-2959. American Society of Hematology
Antonelli, A, Noort, W A, Jaques, J, de Boer, B, de Jong-Korlaar, R, Brouwers-Vos, A Z, Lubbers-Aalders, L, van Velzen, J F, Bloem, A C, Yuan, H, de Bruijn, J D, Ossenkoppele, G J, Martens, A C M, Vellenga, E, Groen, R W J & Schuringa, J J 2016, ' Establishing human leukemia xenograft mouse models by implanting human bone marrow-like scaffold-based niches ', Blood, vol. 128, no. 25, pp. 2949-2959 . https://doi.org/10.1182/blood-2016-05-719021, https://doi.org/10.1182/blood-2016-05719021
To begin to understand the mechanisms that regulate self-renewal, differentiation, and transformation of human hematopoietic stem cells or to evaluate the efficacy of novel treatment modalities, stem cells need to be studied in their own species-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6e65245bc5af4d6523afc0239c8190
https://research.rug.nl/en/publications/5788e57c-1b76-4d71-b7b5-a42955af59bb
https://research.rug.nl/en/publications/5788e57c-1b76-4d71-b7b5-a42955af59bb
Autor:
Joost D. de Bruijn, Richard W.J. Groen, Anton C.M. Martens, Willy A. Noort, Huipin Yuan, Regina de Jong-Korlaar, Constantine S. Mitsiades, Linda Lubbers-Aalders
Publikováno v:
Blood, 126(23). American Society of Hematology
Noort, W A, de Jong-Korlaar, R, Lubbers-Aalders, L, Yuan, H, de Bruijn, J D, Mitsiades, C S, Martens, A C M & Groen, R W J 2015, ' Addition of the Vascular Niche Component to the Human Bone Marrow-like Scaffold Model ', Blood, vol. 126, no. 23 .
Noort, W A, de Jong-Korlaar, R, Lubbers-Aalders, L, Yuan, H, de Bruijn, J D, Mitsiades, C S, Martens, A C M & Groen, R W J 2015, ' Addition of the Vascular Niche Component to the Human Bone Marrow-like Scaffold Model ', Blood, vol. 126, no. 23 .
Previously, we have reported that our human bone marrow (BM)-like scaffold xenograft model allows the engraftment and outgrowth of normal and malignant hematopoiesis (e.g. multiple myeloma (MM), acute myelocytic/lymphocytic leukemia (AML/ALL) and MDS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530b33dff8ae2b201ec80406f2e832aa
https://research.vumc.nl/en/publications/d6ef8959-e9a6-49f0-bc48-eb4cd1e6de1f
https://research.vumc.nl/en/publications/d6ef8959-e9a6-49f0-bc48-eb4cd1e6de1f