Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Linda Lin Yan Wu"'
Autor:
Miao Yang, Yoon Lim, Linda Lin-yan Wu, Ying Sun, Damien J. Keating, Xiao-Jiang Li, Larisa Bobrovskaya, Xin-Fu Zhou, Si Chen, Swarna Lekha Vijayaraj
When BDNF binds to its receptors, TrkB and p75NTR, the BDNF-receptor complex is endocytosed and trafficked to the cell body for downstream signal transduction, which plays a critical role in neuronal functions. Huntingtin-associated protein 1 (HAP1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8367ce3e841266342c670e8535e3e98f
https://hdl.handle.net/11541.2/124178
https://hdl.handle.net/11541.2/124178
Autor:
Robert J. Norman, Rebecca L. Robker, Darryl L. Russell, Kylie R. Dunning, Michelle Lane, Linda Lin Yan Wu, Xing Yang
Publikováno v:
Endocrinology. 151:5438-5445
In obesity, accumulation of lipid in nonadipose tissues, or lipotoxicity, is associated with endoplasmic reticulum (ER) stress, mitochondrial dysfunction, and ultimately apoptosis. We have previously shown that obese women have increased triglyceride
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4362c1e21d8dee87e528c2195fe2f4a8
https://doi.org/10.1210/en.2010-0551
https://doi.org/10.1210/en.2010-0551
Differential effects of pro-BDNF on sensory neurons after sciatic nerve transection in neonatal rats
Publikováno v:
European Journal of Neuroscience. 27:2380-2390
Brain-derived neurotrophic factor (BDNF) plays a critical role in the development of the central and peripheral nervous systems, and also in neuronal survival after injury. The actions of BDNF are mediated by its high-affinity receptors TrkB and p75N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::131c1fa0f4069eddc4f67bcd8fa62222
https://doi.org/10.1111/j.1460-9568.2008.06215.x
https://doi.org/10.1111/j.1460-9568.2008.06215.x
Autor:
Robert A. Rush, Linda Lin-yan Wu, Hui Wang, Xin-Fu Zhou, Xing-Yun Song, Xue-Gang Luo, Jin-Hua Zhong
Publikováno v:
European Journal of Neuroscience. 24:2444-2452
Recent studies have shown that the precursor of brain-derived neurotrophic factor (pro-BDNF) activates p75NTR with high affinity to induce apoptosis. Here we show that pro-BDNF is transported anterogradely and retrogradely in sensory neurons of adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::253ff74cdf6bb14af3af63e44c236716
https://doi.org/10.1111/j.1460-9568.2006.05138.x
https://doi.org/10.1111/j.1460-9568.2006.05138.x
Brain-derived neurotrophic factor (BDNF) plays a pivotal role in brain development and synaptic plasticity. It is synthesized as a precursor (pro-BDNF), sorted into the secretory pathway, transported along dendrites and axons, and released in an acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cc627aece4e86837d2549d0247e7dd
https://hdl.handle.net/11541.2/120762
https://hdl.handle.net/11541.2/120762
Autor:
Linda Lin-yan Wu, Xin-Fu Zhou
Huntington's disease (HD) is caused by a polyglutamine expansion in the protein huntingtin (Htt). Several studies suggest that Htt and huntingtin associated protein 1 (HAP1) participate in intracellular trafficking and that polyglutamine expansion af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efb33a6f083547f9dd39bdbae0641b7
https://hdl.handle.net/11541.2/120830
https://hdl.handle.net/11541.2/120830
Differential effects of pro-BDNF on sensory neurons after sciatic nerve transection in neonatal rats
Publikováno v:
The European journal of neuroscience. 27(9)
Brain-derived neurotrophic factor (BDNF) plays a critical role in the development of the central and peripheral nervous systems, and also in neuronal survival after injury. The actions of BDNF are mediated by its high-affinity receptors TrkB and p75N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0bb58eddb44cae735220fa560fc9b1c1
https://pubmed.ncbi.nlm.nih.gov/18430030
https://pubmed.ncbi.nlm.nih.gov/18430030
Autor:
Hui, Wang, Linda Lin-Yan, Wu, Xing-Yun, Song, Xue-Gang, Luo, Jin-Hua, Zhong, Robert A, Rush, Xin-Fu, Zhou
Publikováno v:
The European journal of neuroscience. 24(9)
Recent studies have shown that the precursor of brain-derived neurotrophic factor (pro-BDNF) activates p75NTR with high affinity to induce apoptosis. Here we show that pro-BDNF is transported anterogradely and retrogradely in sensory neurons of adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81ea463e2100dbd4fab4f9a95156fca1
https://pubmed.ncbi.nlm.nih.gov/17100833
https://pubmed.ncbi.nlm.nih.gov/17100833