Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Linda Löfbom"'
Autor:
Ying Wang, Saikiran K. Sedimbi, Linda Löfbom, Gurdyal S. Besra, Steven A. Porcelli, Susanna L. Cardell
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The glycosphingolipid α-galactosylceramide (α-GalCer) is a well-described immune activator with strong anti-tumor properties in animal models. It is presented on CD1d and acts by stimulating the invariant, type I, natural killer T (iNKT) lymphocyte
Externí odkaz:
https://doaj.org/article/bf1ec3a65d76425fb970a58c40945b05
Publikováno v:
Scandinavian Journal of Immunology
Natural killer T (NKT) cells are αβ T cell receptor (TCR) expressing innate‐like T cells that display natural killer (NK) cell markers. Based on TCR characteristics, they are divided into two groups restricted to the MHC class I‐like molecule C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a3277e1001155a6df2a27bc38d01cc7
https://pubmed.ncbi.nlm.nih.gov/31141185
https://pubmed.ncbi.nlm.nih.gov/31141185
Autor:
Susanna Cardell, Ying Wang, Steven A. Porcelli, Linda Löfbom, Gurdyal S. Besra, Saikiran K. Sedimbi
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
The glycosphingolipid α-galactosylceramide (α-GalCer) is a well described immune activator with strong anti-tumor properties in animal models. It is presented on CD1d and acts by stimulating the invariant, type I, natural killer T (iNKT) lymphocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4497ed77a6bc5f0db2fbce60ad00e8a
https://pubmed.ncbi.nlm.nih.gov/30881361
https://pubmed.ncbi.nlm.nih.gov/30881361
Autor:
Prabhanshu, Tripathi, Saikiran K, Sedimbi, Avadhesh Kumar, Singh, Linda, Löfbom, Shohreh, Issazadeh-Navikas, Siegfried, Weiss, Irmgard, Förster, Mikael C I, Karlsson, Ulf, Yrlid, Nadir, Kadri, Susanna L, Cardell
Publikováno v:
European Journal of Immunology
Natural killer T (NKT) cells recognize glycolipids presented on CD1d. They share features of adaptive T lymphocytes and innate NK cells, and mediate immunoregulatory functions via rapid production of cytokines. Invariant (iNKT) and diverse (dNKT) NKT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56cd161293053da943280a876fa6a413
https://pubmed.ncbi.nlm.nih.gov/30427069
https://pubmed.ncbi.nlm.nih.gov/30427069
Publikováno v:
Scandinavian Journal of Immunology. 79:260-266
The endogenous glycosphingolipid sulfatide is a ligand for CD1d-restricted type II natural killer T (NKT) lymphocytes. Through the action of these cells,sulfatide treatment has been shown to modulate the immune response in mouse models for autoimmune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057a5c20c80e110e399f511204f03fc1
https://doi.org/10.1111/sji.12157
https://doi.org/10.1111/sji.12157
Autor:
Tao Jin, Susanna Cardell, Jan-Eric Månsson, Linda Löfbom, Jakub Kwiecinski, Sara Rhost, Maria Blomqvist
Publikováno v:
Infection and Immunity. 81:1114-1120
Natural killer T (NKT) lymphocytes are implicated in the early response to microbial infection. Further, sulfatide, a myelin self-glycosphingolipid, activates a type II NKT cell subset and can modulate disease in murine models. We examined the role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308fe1dcb1a5475afa6d24be22500bc7
https://doi.org/10.1128/iai.01334-12
https://doi.org/10.1128/iai.01334-12
Autor:
Steven A. Porcelli, Saikiran K. Sedimbi, Susanna Cardell, Linda Löfbom, Avadhesh Kumar Singh, Ying Wang
Publikováno v:
Mucosal immunology
CD1d-restricted invariant natural killer T (iNKT) cells are known as potent early regulatory cells of immune responses. Besides the established roles in the regulation of inflammation and autoimmune disease, studies have shown that iNKT cells have im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403c432fb1a54665762548ff6d2f3ff3
https://pubmed.ncbi.nlm.nih.gov/28401935
https://pubmed.ncbi.nlm.nih.gov/28401935
Autor:
Susanna Cardell, Sara Rhost, Susann Teneberg, Maria Blomqvist, Linda Löfbom, Britt-Marie Rynmark, Jan-Eric Månsson, Bo Pei
Publikováno v:
European Journal of Immunology. 42:2851-2860
Sulfatide-reactive CD1d-restricted natural killer T (NKT) lymphocytes belong to the type II NKT cell subset with diverse TCRs, and have been found to regulate experimental auto-immune encephalomyelitis, tumor immunity, and experimental hepatitis in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4fdc8de25a7980ee7815889e323059c
https://doi.org/10.1002/eji.201142350
https://doi.org/10.1002/eji.201142350
Autor:
Thomas Osterbye, Manfred Brigl, Maria Blomqvist, Jan-Eric Månsson, Susanna Cardell, Susann Teneberg, Sara Rhost, Linda Löfbom
Publikováno v:
European Journal of Immunology. 39:1726-1735
The glycosphingolipid sulfatide (SO3-3Galβ1Cer) is a demonstrated ligand for a subset of CD1d-restricted NKT cells, which could regulate experimental autoimmune encephalomyelitis, a murine model for multiple sclerosis, as well as tumor immunity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7599983f30d38d3db14804526966309
https://doi.org/10.1002/eji.200839001
https://doi.org/10.1002/eji.200839001
CD4(+) type II NKT cells mediate ICOS and programmed death-1-dependent regulation of type 1 diabetes
Autor:
Lydia Sorokin, Linda Löfbom, Shashank Gupta, Hideo Yagita, Susanna Cardell, Agnès Lehuen, Eva Korpos, Nadir Kadri, Christian Boitard, Claire Briet, Dan Holmberg
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 188(7)
Type 1 diabetes (T1D) is a chronic autoimmune disease that results from T cell-mediated destruction of pancreatic β cells. CD1d-restricted NKT lymphocytes have the ability to regulate immunity, including autoimmunity. We previously demonstrated that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0430b178cc91c2434d999b6a11797a5a
https://pubmed.ncbi.nlm.nih.gov/22371394
https://pubmed.ncbi.nlm.nih.gov/22371394