Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Linda Kubat"'
Autor:
Nalini Srinivas, Lukas Peiffer, Kai Horny, Kuan Cheok Lei, Terkild B. Buus, Linda Kubat, Meng Luo, Menghong Yin, Ivelina Spassova, Antje Sucker, Farnoush Farahpour, Jan Kehrmann, Selma Ugurel, Elisabeth Livingstone, Thilo Gambichler, Niels Ødum, Jürgen C. Becker
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundMycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma (CTCL). Comprehensive analysis of MF cells in situ and ex vivo is complicated by the fact that is challenging to distinguish malignant from reactive T cells with
Externí odkaz:
https://doaj.org/article/b05b6c455d114b53a032805bb49cb832
Autor:
Heike Chauvistré, Batool Shannan, Sheena M. Daignault-Mill, Robert J. Ju, Daniel Picard, Stefanie Egetemaier, Renáta Váraljai, Christine S. Gibhardt, Antonio Sechi, Farnusch Kaschani, Oliver Keminer, Samantha J. Stehbens, Qin Liu, Xiangfan Yin, Kirujan Jeyakumar, Felix C. E. Vogel, Clemens Krepler, Vito W. Rebecca, Linda Kubat, Smiths S. Lueong, Jan Forster, Susanne Horn, Marc Remke, Michael Ehrmann, Annette Paschen, Jürgen C. Becker, Iris Helfrich, Daniel Rauh, Markus Kaiser, Sheraz Gul, Meenhard Herlyn, Ivan Bogeski, José Neptuno Rodríguez-López, Nikolas K. Haass, Dirk Schadendorf, Alexander Roesch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Slow-cycling melanoma persister cells are characterised by a high, reversible expression of H3K4 demethylase KDM5B. Here, the authors use genetic and chemical methods to enforce a permanent high expression of KDM5B and show that these cells transit t
Externí odkaz:
https://doaj.org/article/37bb3c7c6ed14e8aa7ac035cb7135585
Autor:
Lukas Peiffer, Thilo Gambichler, Terkild B. Buus, Kai Horny, Jan Gravemeyer, Frauke Furtmann, Ivelina Spassova, Linda Kubat, Laura Susok, René Stranzenbach, Nalini Srinivas, Niels Ødum, Jürgen C. Becker
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundSézary Syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphomas (CTCL). In SS patients, malignant T cells are circulating through the blood and cause erythroderma.ObjectiveTo compare the transcriptome of single cells i
Externí odkaz:
https://doaj.org/article/1510353606f4410580817c6681e83eb9
Autor:
Dirk Schadendorf, Lucie Heinzerling, Jessica C Hassel, Lisa Zimmer, Ralf Gutzmer, Lisa Villabona, Selma Ugurel, Thomas Eigentler, Peter Mohr, Thilo Gambichler, Patrick Terheyden, Sebastian Haferkamp, Claudia Pfoehler, Carmen Loquai, Jürgen Christian Becker, Ulrike Leiter, Hans-Ulrich Schildhaus, Ivelina Spassova, Linda Kubat, Annalena Mohr, Hannah Björn Andtback, Jochen S Utikal, Kai Horny, Daniel Habermann, Daniel Hoffmann
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/9d5ed971c944418f96838e599806293f
Autor:
Jürgen C. Becker, Dirk Schadendorf, Daniel Hoffmann, David Schrama, Rajiv Kumar, Lukas Peiffer, Mohammadkarim Saeedghalati, Farnoush Farahpour, Daniel Habermann, Linda Kubat, Cathrin Ritter, Jessica C. Hassel, Antje Sucker, Patrick Terheyden, Selma Ugurel, Ivelina Spassova
Supplementary Figure S1. CONSORT diagram of the experimental study design.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09714b744e2f7c2eb9a8db59af327f27
https://doi.org/10.1158/1078-0432.22478178
https://doi.org/10.1158/1078-0432.22478178
Autor:
Jürgen C. Becker, Dirk Schadendorf, Daniel Hoffmann, David Schrama, Rajiv Kumar, Lukas Peiffer, Mohammadkarim Saeedghalati, Farnoush Farahpour, Daniel Habermann, Linda Kubat, Cathrin Ritter, Jessica C. Hassel, Antje Sucker, Patrick Terheyden, Selma Ugurel, Ivelina Spassova
Supplementary Table S3. Differentially expressed genes between responders and non-responders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1844075c307fe3b450c361eb4d8d7461
https://doi.org/10.1158/1078-0432.22478154
https://doi.org/10.1158/1078-0432.22478154
Autor:
Jürgen C. Becker, Dirk Schadendorf, Daniel Hoffmann, David Schrama, Rajiv Kumar, Lukas Peiffer, Mohammadkarim Saeedghalati, Farnoush Farahpour, Daniel Habermann, Linda Kubat, Cathrin Ritter, Jessica C. Hassel, Antje Sucker, Patrick Terheyden, Selma Ugurel, Ivelina Spassova
Supplementary material (Bayes Analysis)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc3d96a61cd2874a2202e807d0a9601
https://doi.org/10.1158/1078-0432.22478166
https://doi.org/10.1158/1078-0432.22478166
Autor:
Jürgen C. Becker, Dirk Schadendorf, Daniel Hoffmann, David Schrama, Rajiv Kumar, Lukas Peiffer, Mohammadkarim Saeedghalati, Farnoush Farahpour, Daniel Habermann, Linda Kubat, Cathrin Ritter, Jessica C. Hassel, Antje Sucker, Patrick Terheyden, Selma Ugurel, Ivelina Spassova
Purpose:Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer, which can be effectively controlled by immunotherapy with PD-1/PD-L1 checkpoint inhibitors. However, a significant proportion of patients are characterized by primary th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf06682c1f813c39887d889007fc7ab
https://doi.org/10.1158/1078-0432.c.6529869.v1
https://doi.org/10.1158/1078-0432.c.6529869.v1
Autor:
Kaiji Fan, Nalini Srinivas, Linda Kubat, Jan Gravemeyer, Antje Sucker, Dirk Schadendorf, Thilo Gambichler, Jürgen C Becker
Background Merkel cell carcinoma (MCC) is an aggressive skin tumor with neuroendocrine differentiation. Immunotherapies are very effective in the treatment of advanced stage MCC patients, but for patients whose tumor cannot be controlled by the immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d5a4e4a212e138165bd1d8b09b3eab
https://www.ncbi.nlm.nih.gov/pubmed/36991156
https://www.ncbi.nlm.nih.gov/pubmed/36991156
Autor:
Ivelina Spassova, Daniel Habermann, Linda Kubat, Selma Ugurel, Rajesh Kumar, Jessica C. Hassel, Jürgen C. Becker, Mohammadkarim Saeedghalati, Farnoush Farahpour, Cathrin Ritter, Lukas Peiffer, Patrick Terheyden, Daniel Hoffmann, Dirk Schadendorf, Antje Sucker, David Schrama
Publikováno v:
Clinical Cancer Research. 26:2257-2267
Purpose: Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer, which can be effectively controlled by immunotherapy with PD-1/PD-L1 checkpoint inhibitors. However, a significant proportion of patients are characterized by primary t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118a544457d321110f4b5e3b150a5b97
https://doi.org/10.1158/1078-0432.ccr-19-2244
https://doi.org/10.1158/1078-0432.ccr-19-2244