Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Linda Krug"'
Autor:
Karmveer Singh, Emanuela Camera, Linda Krug, Abhijit Basu, Rajeev Kumar Pandey, Saira Munir, Meinhard Wlaschek, Stefan Kochanek, Marina Schorpp-Kistner, Mauro Picardo, Peter Angel, Catherin Niemann, Pallab Maity, Karin Scharffetter-Kochanek
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Epidermal homeostasis is maintained by the activity of stem cells. Here, the authors show that deficiency of the transcription factor JunB leads to altered Notch signaling in stem cells, resulting in a cell fate switch and de novo formation of aberra
Externí odkaz:
https://doaj.org/article/22e44ec426b3467fbc580f37446b2625
Autor:
Patrick Meyer, Pallab Maity, Andre Burkovski, Julian Schwab, Christoph Müssel, Karmveer Singh, Filipa F Ferreira, Linda Krug, Harald J Maier, Meinhard Wlaschek, Thomas Wirth, Hans A Kestler, Karin Scharffetter-Kochanek
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 12, p e1005741 (2017)
Cells and tissues are exposed to stress from numerous sources. Senescence is a protective mechanism that prevents malignant tissue changes and constitutes a fundamental mechanism of aging. It can be accompanied by a senescence associated secretory ph
Externí odkaz:
https://doaj.org/article/abba4c91a98545e68a452b8fcb3d2189
Autor:
Karmveer Singh, Pallab Maity, Linda Krug, Patrick Meyer, Nicolai Treiber, Tanja Lucas, Abhijit Basu, Stefan Kochanek, Meinhard Wlaschek, Hartmut Geiger, Karin Scharffetter‐Kochanek
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 1, Pp 59-77 (2014)
Abstract The evolutionarily conserved IGF‐1 signalling pathway is associated with longevity, metabolism, tissue homeostasis, and cancer progression. Its regulation relies on the delicate balance between activating kinases and suppressing phosphatas
Externí odkaz:
https://doaj.org/article/bb10b2031a34423eb57773e0845524b8
Autor:
Adelheid Hainzl, Mark A. Kluth, Abhijit Basu, Karmveer Singh, Rajeev Kumar Pandey, Natasha Y. Frank, András Bánvölgyi, Sabine A. Eming, Irena Pastar, Anca Sindrilaru, Christiane Pfeiffer, Norbert Wikonkál, Seppe Vander Beken, Meinhard Wlaschek, Markus H. Frank, Philipp Haas, Marjana Tomic-Canic, Christoph Ganss, Pallab Maity, A. Koroma, Linda Krug, Karin Scharffetter-Kochanek
Publikováno v:
J Invest Dermatol
Severe angiopathy is a major driver for diabetes associated secondary complications. Knowledge on underlying mechanisms essential for advanced therapies to attenuate these pathologies is limited. Injection of ABCB5+ stromal precursors (SPs) at the ed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd704b895810c4bb94cb5dff8c5915b6
https://doi.org/10.1016/j.jid.2021.10.026
https://doi.org/10.1016/j.jid.2021.10.026
Persistent JunB activation in fibroblasts disrupts stem cell niche interactions enforcing skin aging
Autor:
Wilhelm Bloch, Stefan Kochanek, Linda Krug, Peter Angel, Karmveer Singh, Meinhard Wlaschek, Anita Ignatius, Karin Scharffetter-Kochanek, A. Koroma, Pallab Maity, Marina Schorpp-Kistner, Hartmut Geiger, Adelheid Hainzl
Publikováno v:
Cell reports. 36(9)
Fibroblasts residing in the connective tissues constitute the stem cell niche, particularly in organs such as skin. Although the effect of fibroblasts on stem cell niches and organ aging is an emerging concept, the underlying mechanisms are largely u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0d193ac207fd9097efb8368b1187c4
https://pubmed.ncbi.nlm.nih.gov/34469740
https://pubmed.ncbi.nlm.nih.gov/34469740
Autor:
Abhijit Basu, Karmveer Singh, Marjana Tomic-Canic, Mark A. Kluth, Meinhard Wlaschek, Pallab Maity, A. Koroma, Linda Krug, Karin Scharffetter-Kochanek
Publikováno v:
Journal of Investigative Dermatology. 141:S211
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::599a4adecf25f9f7e9a6dc3bf142f88c
https://doi.org/10.1016/j.jid.2021.08.366
https://doi.org/10.1016/j.jid.2021.08.366
Autor:
Stefan Kochanek, Karmveer Singh, Meinhard Wlaschek, M Schorpp Kistner, Linda Krug, Pallab Maity, Karin Scharffetter-Kochanek, A. Koroma, Peter Angel, Wilhelm Bloch
Publikováno v:
Journal of Investigative Dermatology. 141:S206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4876479a18f50f4d5d0cd656ec9d1ddb
https://doi.org/10.1016/j.jid.2021.08.342
https://doi.org/10.1016/j.jid.2021.08.342
Autor:
Karin Scharffetter-Kochanek, Wilhelm Bloch, Karmveer Singh, Abhijit Basu, Stefan Kochanek, Patrick Meyer, Nicolai Treiber, Pallab Maity, Hartmut Geiger, Meinhard Wlaschek, Seppe Vander Beken, Linda Krug
Publikováno v:
Stem Cells. 35:1704-1718
Increased concentrations of reactive oxygen species (ROS) originating from dysfunctional mitochondria contribute to diverse aging-related degenerative disorders. But so far little is known about the impact of distinct ROS on metabolism and fate of st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd3b1ffe026138039312c2bd54521c3
https://doi.org/10.1002/stem.2629
https://doi.org/10.1002/stem.2629
Autor:
Hartmut Geiger, Karin Scharffetter-Kochanek, Karmveer Singh, Saira Munir, Linda Krug, Gudrun Strauss, Dongsheng Jiang, Abhijit Basu, Pallab Maity, Meinhard Wlaschek, Philipp Haas
Publikováno v:
EMBO Reports
EMBO Rep. 21:e48777 (2020)
EMBO Rep. 21:e48777 (2020)
We here address the question whether the unique capacity of mesenchymal stem cells to re‐establish tissue homeostasis depends on their potential to sense pathogen‐associated molecular pattern and, in consequence, mount an adaptive response in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1539177e33481a599b0ade884d138b74
https://pubmed.ncbi.nlm.nih.gov/32162777
https://pubmed.ncbi.nlm.nih.gov/32162777
Autor:
Karmveer Singh, Andre Burkovski, Pallab Maity, Thomas Wirth, Meinhard Wlaschek, Patrick Meyer, Filipa F. Ferreira, Karin Scharffetter-Kochanek, Linda Krug, Christoph Müssel, Julian D. Schwab, Hans A. Kestler, Harald J. Maier
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 13, Iss 12, p e1005741 (2017)
PLoS Computational Biology, Vol 13, Iss 12, p e1005741 (2017)
Cells and tissues are exposed to stress from numerous sources. Senescence is a protective mechanism that prevents malignant tissue changes and constitutes a fundamental mechanism of aging. It can be accompanied by a senescence associated secretory ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca4af31393ab3c47fe36db7bbef4937
http://europepmc.org/articles/PMC5730191
http://europepmc.org/articles/PMC5730191