Prevalence and prognostic impact of comorbidities and peripheral blood indices in sarcomas

Autor: Carlos K. H. Wong, Herbert Ho-Fung Loong, Sampson Sui Chun Kwan, Y.-M. Lau, Gordon C.H. Tang, Linda K.S. Leung, Teresa Tse, Yingjun Zhang, Yihui Wei

Publikováno v: ESMO Open
ESMO Open, Vol 5, Iss 6 (2020)

Background The prognostic impact of comorbidities in patients with sarcomas is not well defined. The aims of this study were to examine the implications of comorbidities and abnormal peripheral blood indices in patients with sarcomas.Methods A popula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1478e153a9fa8e47a2656f08af18121
http://europepmc.org/articles/PMC7678389

Cost-effectiveness analysis of pembrolizumab compared to standard of care as first line treatment for patients with advanced melanoma in Hong Kong

Autor: Raquel Aguiar-Ibáñez, Jason Jen, S. C. Tan, Mary Y.K. Lee, Herbert H. Loong, Carlos K. H. Wong, Jingshu Wang, Linda K.S. Leung

Publikováno v: Cost Effectiveness and Resource Allocation : C/E
Cost Effectiveness and Resource Allocation, Vol 18, Iss 1, Pp 1-14 (2020)

Background Pembrolizumab has been shown to improve overall survival (OS) and progression free survival (PFS) compared to ipilimumab in patients with ipilimumab-naïve advanced melanoma; however, there are no published data on the cost-effectiveness f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9cc1b21e361d5929d458d0b094f52bb
https://doi.org/10.1186/s12962-020-0200-9

Identifying an early indicator of drug efficacy in patients with metastatic colorectal cancer—a prospective evaluation of circulating tumor cells, 18F-fluorodeoxyglucose positron-emission tomography and the RECIST criteria

Autor: Ann D. King, Charles Ming Lok Chan, Wing M. Ho, Anthony T.C. Chan, A. Poon, Linda K.S. Leung, Frankie Kf Mo, Sze Chuen Cesar Wong, Ki Wang, Brigette B.Y. Ma

Publikováno v: Annals of Oncology. 28:1576-1581

Background This study investigated the predictive and prognostic significance of assessing early drug response with both positron-emission computerized tomography (PET-CT) and circulating tumor cells (CTCs) in patients receiving first-line chemothera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5164e1636735060d59633c0e7aabe3
https://doi.org/10.1093/annonc/mdx149

Institutional-based prospective molecular profiling of advanced solid tumours in Hong Kong: A report of 253 cases

Autor: Kenneth C.W. Wong, Brigette B.Y. Ma, K.W.C. Lee, T.-C. Chan, J. Fung, Ka Fai To, K. Ho, A.C.Y. Wong, Daisy Cm Lam, Chit Chow, Winnie Yeo, Herbert H. Loong, Linda K.S. Leung, Stephen L. Chan, Jane Koh, Edwin P. Hui, S.-T. Mok

Publikováno v: Annals of Oncology. 30:ix124-ix125

Background Molecular profiling of tumour tissue to guide treatment of patients (pts) with advanced solid tumours has previously been reported. Most series were reported from large volume academic cancer centres in the West. There is a paucity of data

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eafc0cd1ad10ef49157e9a1bb976fdf9
https://doi.org/10.1093/annonc/mdz431.006

Plasma Epstein–Barr viral DNA load at midpoint of radiotherapy course predicts outcome in advanced-stage nasopharyngeal carcinoma

Autor: Brigette B.Y. Ma, Yuk Ming Dennis Lo, Anthony T.C. Chan, Sing Fai Leung, Frankie Kf Mo, Edwin P. Hui, Kwan Chee Chan, Linda K.S. Leung, Benny Zee, K. W. Chu, Kathy Chow

Publikováno v: Annals of Oncology. 25:1204-1208

BACKGROUND To test the hypothesis that prognostication of treatment outcome is feasible by biomarker response at midcourse of chemoradiotherapy (CRT)/radiotherapy (RT), with respect to the plasma load of Epstein-Barr viral (EBV) DNA in nasopharyngeal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2837552666b9382b37a9b9928daeb3
https://doi.org/10.1093/annonc/mdu117