Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Linda K. Myers"'
Autor:
Wei Dong, Cheng Tian, Z. Galvin Li, Matthew Bounds, Jiamin Ma, David D. Brand, Xiaoyun Liu, Yanhong Cao, Arielle Beard, Jian Yan, Karen Hasty, John Stuart, Kui Li, Hongsik Cho, Elizabeth A. Fitzpatrick, Linda K. Myers, Yan Jiao, Weikuan Gu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract When IL-1 receptor antagonist (IL-1rn) is knocked out, mice have shown strain background dependent and major QTL regulated susceptibility to spontaneously inflammatory arthritis disease (SAD). The impact on bone properties resulting from the
Externí odkaz:
https://doaj.org/article/a142c5c0a9554584a4639c96315f0450
Autor:
Wei Dong, Cheng Tian, Z. Galvin Li, David Brand, Yanhong Cao, Xiaoyun Liu, Jiamin Ma, Andy Chai, Linda K. Myers, Jian Yan, Karen Hasty, John Stuart, Yan Jiao, Weikuan Gu, Xiaojun Cai
Publikováno v:
Laboratory Animal Research, Vol 39, Iss 1, Pp 1-9 (2023)
Abstract Sex difference has shown in the arthritis diseases in human population and animal models. We investigate how the sex and symmetry vary among mouse models with different genomic backgrounds. Disease data of sex and limbs accumulated in the pa
Externí odkaz:
https://doaj.org/article/2e651b699e3d42939daf63ce8d6455b7
Autor:
Wei Dong, Bradley C. Postlethwaite, Patricia A. Wheller, David Brand, Yan Jiao, Wei Li, Linda K. Myers, Weikuan Gu
Publikováno v:
Bone & Joint Research, Vol 11, Iss 8, Pp 528-540 (2022)
AimsThis study investigated the effects of β-caryophyllene (BCP) on protecting bone from vitamin D deficiency in mice fed on a diet either lacking (D-) or containing (D+) vitamin D.MethodsA total of 40 female mice were assigned to four treatment gro
Externí odkaz:
https://doaj.org/article/247888afbcb84fa984ab7b16669bc089
Autor:
Linda K. Myers, Ying-Xin Ouyang, Jay R. Patel, Herman H. Odens, Virginia Woo-Rasberry, Jeoungeun Park, Ae-Kyung Yi, Edward F. Rosloniec, David D. Brand, John M. Stuart, Andrew H. Kang
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9833 (2022)
Citrullination of proteins plays an important role in protein function and it has recently become clear that citrullinated proteins play a role in immune responses. In this study we examined how citrullinated collagen, an extracellular matrix protein
Externí odkaz:
https://doaj.org/article/6de55cf3bbcc4a6ca807fa958fa94234
Autor:
Arnold E. Postlethwaite, Robert C. Tuckey, Tae-Kang Kim, Wei Li, Syamal K. Bhattacharya, Linda K. Myers, David D. Brand, Andrzej T. Slominski
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The ability to use large doses of vitamin D3 (D3) to chronically treat autoimmune diseases such as rheumatoid arthritis (RA) is prohibitive due to its calcemic effect which can damage vital organs. Cytochrome P450scc (CYP11A1) is able to convert D3 i
Externí odkaz:
https://doaj.org/article/fa1661234a1b494fb2fa119c0157414a
Autor:
Linda K. Myers, Michael Winstead, John D. Kee, Jeoungeun J. Park, Sicheng Zhang, Wei Li, Ae-Kyung Yi, John M. Stuart, Edward F. Rosloniec, David D. Brand, Robert C. Tuckey, Andrzej T. Slominski, Arnold E. Postlethwaite, Andrew H. Kang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13342 (2021)
Vitamin D plays a crucial role in regulation of the immune response. However, treatment of autoimmune diseases with 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] doses sufficient to be effective is prohibitive due to its calcemic and toxic effects. We use t
Externí odkaz:
https://doaj.org/article/6c8ae4b7289f4d74854e8298c05abd98
Autor:
Monica L. Brown Lobbins, Andrzej T. Slominski, Karen A. Hasty, Sicheng Zhang, Duane D. Miller, Wei Li, Tae-Kang Kim, Zorica Janjetovic, Robert C. Tuckey, Imara-Safi O. Scott, Linda K. Myers, Arnold E. Postlethwaite
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 367 (2021)
We previously demonstrated that the non-calcemic pregnacalciferol (pD) analog 17,20S (OH)2pD suppressed TGF-β1-induced type I collagen production in cultured normal human dermal fibroblasts. In the present studies, we examined fibroblasts cultured f
Externí odkaz:
https://doaj.org/article/c7bce4db2efe4d68b05ba81c56c86282
Autor:
Monica L. Brown Lobbins, Imara-Safi O. Scott, Andrzej T. Slominski, Karen A. Hasty, Sicheng Zhang, Duane D. Miller, Wei Li, Tae-Kang Kim, Zorica Janjetovic, Tejesh S. Patel, Linda K. Myers, Arnold E. Postlethwaite
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8926 (2021)
Systemic sclerosis (SSc; scleroderma) is a chronic fibrotic disease involving TGF-β1. Low serum vitamin D (vit D) correlates with the degree of fibrosis and expression of TGF-β1. This study was designed to determine whether the noncalcemic vit D an
Externí odkaz:
https://doaj.org/article/586caac290d64398abc0326b37197255
Autor:
Monica L, Brown Lobbins, Andrzej T, Slominski, Karen A, Hasty, Sicheng, Zhang, Duane D, Miller, Wei, Li, Tae-Kang, Kim, Zorica, Janjetovic, Robert C, Tuckey, Imara-Safi O, Scott, Linda K, Myers, Arnold E, Postlethwaite
Publikováno v:
International Journal of Molecular Sciences
We previously demonstrated that the non-calcemic pregnacalciferol (pD) analog 17,20S (OH)2pD suppressed TGF-β1-induced type I collagen production in cultured normal human dermal fibroblasts. In the present studies, we examined fibroblasts cultured f
Autor:
Andrzej Slominski, Imara-Safi O Scott, Duane D. Miller, Zorica Janjetovic, Wei Li, Arnold E. Postlethwaite, Linda K. Myers, Sicheng Zhang, Tejesh Patel, Monica L Brown Lobbins, Karen A. Hasty, Tae Kang Kim
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8926, p 8926 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8926, p 8926 (2021)
Systemic sclerosis (SSc
scleroderma) is a chronic fibrotic disease involving TGF-β1. Low serum vitamin D (vit D) correlates with the degree of fibrosis and expression of TGF-β1. This study was designed to determine whether the noncalcemic vit
scleroderma) is a chronic fibrotic disease involving TGF-β1. Low serum vitamin D (vit D) correlates with the degree of fibrosis and expression of TGF-β1. This study was designed to determine whether the noncalcemic vit