Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Linda K. Lee"'
Autor:
Tau-Hong Lee, Joshua G X Wong, Yee-Sin Leo, Tun-Linn Thein, Ee-Ling Ng, Linda K Lee, David C Lye
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 3, p e0004576 (2016)
BACKGROUND:Thrombocytopenia is a hallmark of dengue infection, and bleeding is a dreaded complication of dengue fever. Prophylactic platelet transfusion has been used to prevent bleeding in the management of dengue fever, although the evidence for it
Externí odkaz:
https://doaj.org/article/cc04fedeee284607bfe1b7f45a814ac7
Autor:
Emily K Rowe, Yee-Sin Leo, Joshua G X Wong, Tun-Linn Thein, Victor C Gan, Linda K Lee, David C Lye
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 4, p e2777 (2014)
BACKGROUND/METHODS: To better understand dengue fever in the elderly, we compared clinical features, World Health Organization (WHO) dengue classification and outcomes between adult (
Externí odkaz:
https://doaj.org/article/1da895f2b6f7442782e00fcb720850a6
Autor:
Farhad F Vasanwala, Tun-Linn Thein, Yee-Sin Leo, Victor C Gan, Ying Hao, Linda K Lee, David C Lye
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 2, p e2712 (2014)
BACKGROUND: Dengue is an important viral infection with different presentations. Predicting disease severity is important in triaging patients requiring hospital care. We aim to study the value of proteinuria in predicting the development of dengue h
Externí odkaz:
https://doaj.org/article/56e6fab21a7a4ca38bcf681a0d03ee2a
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 6, p e1676 (2012)
BACKGROUND: Elevation of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) is prominent in acute dengue illness. The World Health Organization (WHO) 2009 dengue guidelines defined AST or ALT ≥ 1000 units/liter (U/L) as a criterion
Externí odkaz:
https://doaj.org/article/c29bf85825e9445abed0fa88c17bedb0
Autor:
Luis R Carrasco, Linda K Lee, Vernon J Lee, Eng Eong Ooi, Donald S Shepard, Tun L Thein, Victor Gan, Alex R Cook, David Lye, Lee Ching Ng, Yee Sin Leo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 12, p e1426 (2011)
BACKGROUND: Dengue illness causes 50-100 million infections worldwide and threatens 2.5 billion people in the tropical and subtropical regions. Little is known about the disease burden and economic impact of dengue in higher resourced countries or th
Externí odkaz:
https://doaj.org/article/12ad08001f2e4429b5b495631a668ac9
Autor:
Lisa F. P. Ng, Fok-Moon Lum, Andres Merits, Linda K. Lee, Siew-Wai Fong, Yee Sin Leo, Chia Yin Chong, David C. Lye, Cui Lin, Raymond Tzer-Pin Lin, Teck-Hui Teo, Tze Minn Mak, Olga Y Susova
Publikováno v:
The Journal of Infectious Diseases
Summary The reemergence of Zika virus (ZIKV) warrants the need to develop complementary diagnostic measures. In this study, flow cytometry was used to determine the presence of ZIKV NS3 antigen in blood monocytes from ZIKV-infected patients
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Autor:
Vincent Jun-Xiong Pang, Chia Yin Chong, Yee Sin Leo, Jeslin J. L. Tan, Vanessa W. Lim, Bernett Lee, David C. Lye, Po Ying Chia, Yiu-Wing Kam, Linda K. Lee, Lisa F. P. Ng, Wearn-Xin Yee, Esther Wing Hei Mok, Fok-Moon Lum, Tze-Kwang Chua, Siti Naqiah Amrun, Wei-Ping Ling
Publikováno v:
The Journal of Infectious Diseases
Understanding the host immune response during Zika virus (ZIKV) infection will provide valuable insights into ZIKV immunopathogenesis. In this study, characterization of cellular changes and immune mediators of ZIKV-infected patients was performed, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8275364aecf5ea6dba02614c43091c70
https://hdl.handle.net/10356/87188
https://hdl.handle.net/10356/87188
Autor:
SIgN Immunomonitoring Platform, Yiu-Wing Kam, Laurent Rénia, Tun-Linn Thein, David C. Lye, Yee Sin Leo, Jeslin J. L. Tan, Zhisheng Her, Victor C. Gan, Linda K. Lee, Lisa F. P. Ng, Katja Fink, Bernett Lee
Publikováno v:
JOURNAL OF INFECTIOUS DISEASES
Background Dengue virus infection typically causes mild dengue fever, but, in severe cases, life-threatening dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) occur. The pathophysiological hallmark of DHF and DSS is plasma leakage that l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967b29140e4219f725570096bed51ef8
Autor:
Yee Sin Leo, Luis R. Carrasco, Tun L. Thein, Vernon J. Lee, Victor C. Gan, David C. Lye, Arul Earnest, Linda K. Lee
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene
Background Previously, most dengue cases in Singapore were hospitalized despite low incidence of dengue hemorrhagic fever (DHF) or death. To minimize hospitalization, the Communicable Disease Centre at Tan Tock Seng Hospital (TTSH) in Singapore imple
Publikováno v:
Annals of the Academy of Medicine, Singapore. 41:577-580
Introduction: The incidence of newly diagnosed older patients diagnosed with human immunodeficiency virus (HIV) has increased worldwide in recent years. In this study, we compared the demographics and clinical presentation of younger and older patien