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pro vyhledávání: '"Linda K. Hutchinson"'
Publikováno v:
The Journal of Organic Chemistry. 58:7883-7890
The Menschutkin-type alkylation of substituted N-methylanilines with methyl arene sulfonates is compared to the same reaction with substituted N-phenylhydroxylamines. The a-effects are small but measurable. The Hammett p parameters are not useful in
Autor:
Elaine Sanders-Bush, Ronald B. Emeson, Hervé Canton, Susan M. Rueter, Linda K. Hutchinson, Hsin Chu, Colleen M. Burns
Publikováno v:
Nature. 387(6630)
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) elicits a wide array of physiological effects by binding to several receptor subtypes. The 5-HT2 family of receptors belongs to a large group of seven-transmembrane-spanning G-protein-coupled