Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Linda K Dixon"'
Autor:
Lynnette C Goatley, Graham Freimanis, Chandana Tennakoon, Thomas J Foster, Mehnaz Quershi, Linda K Dixon, Carrie Batten, Jan Hendrik Forth, Abel Wade, Christopher Netherton
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0293049 (2024)
African swine fever (ASF) is a devastating disease of domestic pigs that has spread across the globe since its introduction into Georgia in 2007. The etiological agent is a large double-stranded DNA virus with a genome of 170 to 180 kb in length depe
Externí odkaz:
https://doaj.org/article/eb29ac9bad5c405580bbe1293747c21f
Autor:
Sonny A. Bacigalupo, Yu‐mei Chang, Linda K. Dixon, Simon Gubbins, Adam J. Kucharski, Julian A. Drewe
Publikováno v:
Ecology and Evolution, Vol 12, Iss 6, Pp n/a-n/a (2022)
Abstract Predicting the likelihood of wildlife presence at potential wildlife–livestock interfaces is challenging. These interfaces are usually relatively small geographical areas where landscapes show large variation over small distances. Models o
Externí odkaz:
https://doaj.org/article/5fd183d8bba64e259e66fc15bda2edd0
Publikováno v:
PeerJ, Vol 8, p e10221 (2020)
Wild animals are the source of many pathogens of livestock and humans. Concerns about the potential transmission of economically important and zoonotic diseases from wildlife have led to increased surveillance at the livestock-wildlife interface. Kno
Externí odkaz:
https://doaj.org/article/d581bda1f3374c1897cc8afb53c650e8
Publikováno v:
Viruses, Vol 13, Iss 8, p 1473 (2021)
African swine fever virus causes a frequently fatal disease of domestic pigs and wild boar that has a high economic impact across 3 continents. The large double-stranded DNA genome codes for approximately 160 proteins. Many of these have unknown func
Externí odkaz:
https://doaj.org/article/c0e908cff86f4940b563721fabb46532
Autor:
Christopher L. Netherton, Lynnette C. Goatley, Ana Luisa Reis, Raquel Portugal, Rachel H. Nash, Sophie B. Morgan, Lynden Gault, Raquel Nieto, Veronica Norlin, Carmina Gallardo, Chak-Sum Ho, Pedro J. Sánchez-Cordón, Geraldine Taylor, Linda K. Dixon
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
African swine fever (ASF) is a lethal haemorrhagic disease of domestic pigs for which there is no vaccine. Strains of the virus with reduced virulence can provide protection against related virulent strains of ASFV, but protection is not 100% and the
Externí odkaz:
https://doaj.org/article/b10c042a55054a12bf5f5e5e02d4fe09
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Pathogen transmission from wildlife hosts to genetically distinct species is a major driver of disease emergence. African swine fever virus (ASFV) persists in sub-Saharan Africa through a sylvatic cycle between warthogs and soft ticks that infest the
Externí odkaz:
https://doaj.org/article/f8ec16df41c443fdbf2e85d1bf8ff256
Autor:
Ana Luisa Reis, Anusyah Rathakrishnan, Leah V. Goulding, Claire Barber, Lynnette C. Goatley, Linda K. Dixon
African swine fever virus encodes proteins that inhibit apoptosis including one member of the BCL-2 family, A179L. Deletion of the A179L gene from the virulent genotype I isolate Benin 97/1 compared to Benin 97/1 expressing A179L or mock-infected mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19088f56a4a8a0d884211d8650894ac4
https://doi.org/10.1101/2023.04.27.538639
https://doi.org/10.1101/2023.04.27.538639
Autor:
Pedro J. Sánchez-Cordón, Tobias Floyd, Daniel Hicks, Helen R. Crooke, Stephen McCleary, Ronan R. McCarthy, Rebecca Strong, Linda K. Dixon, Aleksija Neimanis, Emil Wikström-Lassa, Dolores Gavier-Widén, Alejandro Núñez
Publikováno v:
Pathogens, Vol 10, Iss 6, p 768 (2021)
The understanding of the pathogenic mechanisms and the clinicopathological forms caused by currently circulating African swine fever virus (ASFV) isolates is incomplete. So far, most of the studies have been focused on isolates classified within geno
Externí odkaz:
https://doaj.org/article/4099986baf064aec98e8ed4200cbe95a
Publikováno v:
Viruses, Vol 12, Iss 6, p 615 (2020)
African swine fever (ASF) is a devastating disease in pigs, with no vaccines for control. The genetic manipulation of African swine fever virus (ASFV) is often tedious and time consuming. Here, we describe a method to manipulate the virus genome to p
Externí odkaz:
https://doaj.org/article/590dee06f31648be9e869d0ffcba9e7e
Autor:
Lynnette C. Goatley, Ana Luisa Reis, Raquel Portugal, Hannah Goldswain, Gareth L. Shimmon, Zoe Hargreaves, Chak-Sum Ho, María Montoya, Pedro J. Sánchez-Cordón, Geraldine Taylor, Linda K. Dixon, Christopher L. Netherton
Publikováno v:
Vaccines, Vol 8, Iss 2, p 234 (2020)
Classical approaches to African swine fever virus (ASFV) vaccine development have not been successful; inactivated virus does not provide protection and use of live attenuated viruses generated by passage in tissue culture had a poor safety profile.
Externí odkaz:
https://doaj.org/article/1f0f5742798b481e90c028ba32f7d3a9