Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Linda K, McEvoy"'
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background APOE4 is the strongest genetic risk factor for sporadic Alzheimer’s disease (AD), whereas APOE2 confers protection. However, effects of APOE on neurodegeneration in cognitively intact individuals, and how these associations evol
Externí odkaz:
https://doaj.org/article/53924a62cf944840b623159d9dc7664e
Autor:
Nicole M. Gatto, Anne Renz, Sarah E. Tom, Mary Lyons, Jennifer A. Macuiba, Tammy S. Dodd, Bonnie K. Lind, Shelly L. Gray, Kelly Meyers, Eric B. Larson, Jennifer C. Nelson, Linda K. McEvoy, Sundary Sankaran, Dustin Key, Jeremiah A. Litondo, Paul K. Crane
Publikováno v:
Brain Sciences, Vol 14, Iss 11, p 1075 (2024)
Background: Adult Changes in Thought (ACT), a prospective cohort study, enrolls older adult members of Kaiser Permanente Washington. We describe an ambitious project to abstract medical records facilitating epidemiological investigation. Methods: Abs
Externí odkaz:
https://doaj.org/article/8864eb05fb73452cbb7b6e0dddf45220
Autor:
Alexander Ivan B. Posis, John E. Alcaraz, Humberto Parada, Aladdin H. Shadyab, Jeremy A. Elman, Matthew S. Panizzon, Chandra A. Reynolds, Carol E. Franz, William S. Kremen, Linda K. McEvoy
Publikováno v:
Neurotrauma Reports, Vol 5, Iss 1, Pp 563-000 (2024)
Traumatic brain injury (TBI) is associated with increased risk of dementia. However, whether TBI is associated with greater cognitive decline over time in specific cognitive domains among older adults is not well understood. This prospective cohort s
Externí odkaz:
https://doaj.org/article/165fee370ce3438c93077f5f7a106628
Autor:
Erin L. Richard, Linda K. McEvoy, Ian J. Deary, Gail Davies, Steven Y. Cao, Eyal Oren, John E. Alcaraz, Andrea Z. LaCroix, Jan Bressler, Rany M. Salem
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Chronic kidney disease has been linked to worse cognition. However, this association may be dependent on the marker of kidney function used, and studies assessing modification by genetics are lacking. This study examined associati
Externí odkaz:
https://doaj.org/article/8ab980b038994d14915a6aa761607d97
Autor:
Daniel E. Gustavson, Derek B. Archer, Jeremy A. Elman, Olivia K. Puckett, Christine Fennema-Notestine, Matthew S. Panizzon, Niranjana Shashikumar, Timothy J. Hohman, Angela L. Jefferson, Lisa T. Eyler, Linda K. McEvoy, Michael J. Lyons, Carol E. Franz, William S. Kremen
Publikováno v:
NeuroImage: Clinical, Vol 37, Iss , Pp 103279- (2023)
Background: Studies have investigated white matter microstructure in relation to late-life cognitive impairments, with fractional anisotropy (FA) and mean diffusivity (MD) measures thought to capture demyelination and axonal degradation. However, new
Externí odkaz:
https://doaj.org/article/355ebd3acd9a443ea48e863f22872254
Autor:
Nathan A. Gillespie, Sean N. Hatton, Donald J. Hagler, Anders M. Dale, Jeremy A. Elman, Linda K. McEvoy, Lisa T. Eyler, Christine Fennema-Notestine, Mark W. Logue, Ruth E. McKenzie, Olivia K. Puckett, Xin M. Tu, Nathan Whitsel, Hong Xian, Chandra A. Reynolds, Matthew S. Panizzon, Michael J. Lyons, Michael C. Neale, William S. Kremen, Carol Franz
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Magnetic resonance imaging data are being used in statistical models to predicted brain ageing (PBA) and as biomarkers for neurodegenerative diseases such as Alzheimer’s Disease. Despite their increasing application, the genetic and environmental e
Externí odkaz:
https://doaj.org/article/c4ea124e5d2448f795e1f2eec8e76a19
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2, p e1009903 (2022)
Integration of multi-omics data with molecular interaction networks enables elucidation of the pathophysiology of Alzheimer's disease (AD). Using the latest genome-wide association studies (GWAS) including proxy cases and the STRING interactome, we i
Externí odkaz:
https://doaj.org/article/a2ec64c1dede42b08994ad8da998a0f1
Autor:
Hao Wang, Min-Tzu Lo, Sara Brin Rosenthal, Carolina Makowski, Ole A. Andreassen, Rany M. Salem, Linda K. McEvoy, Mark Fiecas, Chi-Hua Chen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Sex differences have been observed in the clinical manifestations of Alzheimer’s disease (AD) and elucidating their genetic basis is an active research topic. Based on autosomal genotype data of 7,216 men and 10,680 women, including 8,136 AD cases
Externí odkaz:
https://doaj.org/article/0d2d36e5fa174695b7eedae01d615dd1
Autor:
Hao Wang, Brin Sara Rosenthal, Carolina Makowski, Min‐Tzu Lo, Ole A. Andreassen, Rany M. Salem, Linda K. McEvoy, Mark Fiecas, Chi‐Hua Chen
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Sex‐dependent risk factors may underlie sex differences in Alzheimer's disease (AD). Methods Using sex‐stratified genome‐wide association studies (GWAS) of AD, we evaluated associations of 12 traits with AD through polygen
Externí odkaz:
https://doaj.org/article/62aebdb3f59b44c19bb4907bd8960c2f
Autor:
Alexander Ivan B, Posis, Natalie M, Yarish, Linda K, McEvoy, Purva, Jain, Candyce H, Kroenke, Nazmus, Saquib, Farha, Ikramuddin, Peter F, Schnatz, John, Bellettiere, Stephen R, Rapp, Mark A, Espeland, Aladdin H, Shadyab
Publikováno v:
J Alzheimers Dis
Background: Social support may be a modifiable risk factor for cognitive impairment. However, few long-term, large prospective studies have examined associations of various forms of social support with incident mild cognitive impairment (MCI) and dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f741c07dcacaadbfe05fefb06f9235c8
https://doi.org/10.3233/jad-220967
https://doi.org/10.3233/jad-220967