Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Linda Johanna Aleida Hendriks"'
Autor:
Steven M. Albelda, Steef Engels, Soyeon Kim, Alla Volgina, Floris Fransen, Linda Johanna Aleida Hendriks, Cecile Geuijen, Shane Harvey, Horacio Nastri, Reid Huber, Leslie Hall, Gregory Hollis, John de Kruif, Jing Zhou, Abdul Basmeleh, Pieter Fokko Van Loo, Mark Throsby, Edmund K. Moon, Arjen Kramer, Willem Bartelink, Eric Rovers, Paul Tacken, Hans van der Maaden, Vanessa Zondag-van der Zande, Cheng Yen Huang, Rinse Klooster, Liang Chuan Wang, Ashwini Kulkarni, Chrysi Kanellopoulou, Marina Martinez, Wilfred E. Marissen, Shaun O'Brien, Alexander Berthold Hendrik Bakker, Ton Logtenberg, Renate den Blanken-Smit, Shaun Stewart, Peggy Scherle, Arpita Mondal, Patrick Mayes, Yao bin Liu, Thomas Condamine
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Immune checkpoint inhibitors demonstrate clinical activity in many tumor types, however, only a fraction of patients benefit. Combining CD137 agonists with these inhibitors increases anti-tumor activity preclinically, but attempts to translate these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69ccb4c8aa2845dfcef907bf76c0bc4
http://europepmc.org/articles/PMC8295259
http://europepmc.org/articles/PMC8295259
Autor:
Cecile Geuijen, Floris Fransen, Renate den Blanken-Smit, Ton Logtenberg, Vanessa Zondag-van der Zande, Thomas Condamine, Arjen Kramer, Willem Bartelink, Mark Throsby, Pieter Fokko Van Loo, Liang-Chuan Wang, Yao-Bin Liu, Ashwini Kulkarni, Chrysi Kanellopoulou, Rinse Klooster, Simon Plyte, Wilfred E. Marissen, Linda Johanna Aleida Hendriks, Arpita Mondal, Abdul Basmeleh, Shane Harvey, Lex Bakker, Leslie Hall, Jing Zhou, Paul Tacken, Eric Rovers, Hans van der Maaden, Steef Engels, Shaun Stewart, Patrick Mayes, Cheng-Yen Huang, Alla Volgina, Horacio Nastri
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background MCLA-145 is a CD137 x PD-L1 bispecific antibody that releases PD-L1 mediated T-cell inhibition and activates and expands T cells through agonism of CD137. Immune checkpoint inhibitors (ICI) against PD-(L)1 have demonstrated anti-tumor effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1182175d9e81f991933499ca20ee001a
https://doaj.org/article/3ac9962628b4422ba42992da2d11038e
https://doaj.org/article/3ac9962628b4422ba42992da2d11038e
Autor:
Linda Johanna Aleida Hendriks, John de Kruif, Tristan Gallenne, David Andre Baptiste Maussang-Detaille, Jan P. Gerlach, Mark Throsby, Cecile Geuijen, Arjen Kramer
Publikováno v:
Cancer Research. 81:957-957
HER2-driven cancers require phosphatidylinositide-3 kinase (PI3K)/Akt signaling through HER3 to promote tumor growth and survival. The HER2/HER3 complex is most active in the presence of heregulin (HRG) and upregulation of HRG is one of the key resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1870ef6a23712987a502e0c5dd841105
https://doi.org/10.1158/1538-7445.am2021-957
https://doi.org/10.1158/1538-7445.am2021-957
Autor:
Harry Dolstra, Andres Sirulnik, Rob Roovers, Alexander Berthold Hendrik Bakker, Linda Johanna Aleida Hendriks, Arjen Kramer, M. Leenders, Mark Throsby, Pieter Fokko Van Loo, Basav N. Hangalapura, John de Kruif, Henrike Veninga, Soley Thordardottir, Robert Doornbos, Ton Logtenberg, John D Gibbins
Publikováno v:
Expert Opinion on Biological Therapy, 19, 721-733
Expert Opinion on Biological Therapy, 19(7), 721. Informa Healthcare
Expert Opinion on Biological Therapy, 19, 7, pp. 721-733
Expert Opinion on Biological Therapy, 19(7), 721. Informa Healthcare
Expert Opinion on Biological Therapy, 19, 7, pp. 721-733
Objective: We report the characterization of MCLA-117, a novel T cell-redirecting antibody for acute myeloid leukaemia (AML) treatment targeting CD3 on T cells and CLEC12A on leukaemic cells. In AML, CLEC12A is expressed on blasts and leukaemic stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90820939a92daf92169026666cef0b2b
https://dspace.library.uu.nl/handle/1874/390555
https://dspace.library.uu.nl/handle/1874/390555
Autor:
Ton Logtenberg, Camilla De Nardis, Mark Throsby, Lex Bakker, Cecile Geuijen, Eric Rovers, John de Kruif, Robert Doornbos, Piet Gros, Carina Bartelink-Clements, David Andre Baptiste Maussang-Detaille, Linda Johanna Aleida Hendriks, Tristan Gallenne
Publikováno v:
Cancer Research. 77:33-33
Introduction: MCLA-128 is as an ADCC-enhanced IgG1 bispecific antibody that targets the HER2:HER3 dimer and is currently being tested in Phase I/II clinical trials. MCLA-128 demonstrates an in vitro potency superior to other anti-HER2 and anti-HER3 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d70c6a05d8eeeb50ed0c9ea3212800b9
https://doi.org/10.1158/1538-7445.am2017-33
https://doi.org/10.1158/1538-7445.am2017-33
Autor:
Alexander Berthold Hendrik Bakker, Linda Johanna Aleida Hendriks, Esther van Duijn, Sara Rosati, John de Kruif, Arjan Barendregt, Natalie J. Thompson, Mark Throsby, Albert J. R. Heck
Publikováno v:
Analytical chemistry. 84(16)
Native mass spectrometry was evaluated for the qualitative and semiquantitative analysis of composite mixtures of antibodies representing biopharmaceutical products coexpressed from single cells. We show that by using automated peak fitting of the io
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a1dbb3308dc345a9bbdab2559a367c
https://pubmed.ncbi.nlm.nih.gov/22882109
https://pubmed.ncbi.nlm.nih.gov/22882109