Threonine Deprivation Rapidly Activates the System A Amino Acid Transporter in Primary Cultures of Rat Neurons from the Essential Amino Acid Sensor in the Anterior Piriform Cortex

Autor: Daniel Tomé, Thomas J. Koehnle, Dorothy W. Gietzen, Jean-François Huneau, Anne Blais, Linda J. Magrum, James W. Sharp

Publikováno v: Journal of Nutrition
Journal of Nutrition, American Society for Nutrition, 2003, 133 (7), pp.2156-2164. ⟨10.1093/jn/133.7.2156⟩

Omnivores show recognition of essential (indispensable) amino acid deficiency by changing their feeding behavior within 20 min, yet the cellular mechanisms of amino acid sensation in eukaryotes are poorly understood. The anterior piriform cortex (APC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36010838efdf554171a657a64ef21b6a
https://doi.org/10.1093/jn/133.7.2156

GABAA and GABAB receptors in the anterior piriform cortex modulate feeding in rats

Autor: Dorothy W. Gietzen, Linda J. Magrum, Ban G Truong

Publikováno v: Brain Research. 924:1-9

The effects of GABA(A) and GABA(B) receptors in the anterior piriform cortex (APC) on intake of an amino acid imbalanced diet and a basal diet were evaluated in rats. Administration of muscimol (GABA(A) receptor agonist) to the APC immediately suppre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53f9bfde2684f761f903afb00a7d9cd
https://doi.org/10.1016/s0006-8993(01)03213-9

Increased Intracellular Calcium in Rat Anterior Piriform Cortex in Response to Threonine After Threonine Deprivation

Autor: M. Anne Hickman, Dorothy W. Gietzen, Linda J. Magrum

Publikováno v: Journal of Neurophysiology. 81:1147-1149

Increased intracellular calcium in rat anterior piriform cortex in response to threonine after threonine deprivation The anterior piriform cortex (APC) may serve as the chemosensor for amino acid (AA) deficiency in rats. To investigate the mechanism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602afb7a084ae4493f3517039886be65
https://doi.org/10.1152/jn.1999.81.3.1147

Augmented insulinotropic action of arachidonic acid through the lipoxygenase pathway in the obese Zucker rat

Autor: Stephen D. Phinney, Patricia R. Johnson, Stephanie F. Greene, Linda J. Magrum, Judith S. Stern, Peter J. Havel, Bo Ahrén

Publikováno v: Ahrén, B; Magrum, LJ; Havel, PJ; Greene, SF; Phinney, SD; Johnson, PR; et al.(2000). Augmented insulinotropic action of arachidonic acid through the lipoxygenase pathway in the obese Zucker rat.. Obesity research, 8(6), 475-480. doi: 10.1038/oby.2000.59. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/13t35730
Obesity research, vol 8, iss 6

Objective: The metabolism of arachidonic acid (AA) has been shown to be altered in severe insulin resistance that is present in obese (fa/fa) Zucker rats. We examined the effects and mechanism of action of AA on basal and glucose-stimulated insulin s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482cec2d9d7ec123cf9a999e7fc092ae
http://www.escholarship.org/uc/item/13t35730

Positive modulation of the adipoconversion of adipoblasts derived from genetically obese rats by sodium butyrate

Autor: M. R. C. Greenwood, Francine M. Gregoire, Patricia R. Johnson, Linda J. Magrum

Publikováno v: Obesity research. 2(2)

Using a new serum-free primary culture system, we have previously reported genotypic differences between adipoblasts derived from the epididymal adipose deposit of lean and obese 8-week-old Zucker and Wistar Diabetic Fatty (WDF) rats (15). In these s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c67b82e65ebdd5e59ac6a5593213fe
https://pubmed.ncbi.nlm.nih.gov/16355485