Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Linda J. Krebs"'
Autor:
Linda J. Krebs, Andrew Arnold
Publikováno v:
Current Drug Targets - Immune, Endocrine & Metabolic Disorders. 2:167-179
Our appreciation of the molecular pathogenesis of primary hyperparathyroidism (HPT) has seen great advances over the past decade. This improved understanding may well lead to the development of new treatment options that are specifically targeted to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6992be08678178456cdce33fb44c0b16
https://doi.org/10.2174/1568008023340686
https://doi.org/10.2174/1568008023340686
Autor:
Xiaopeng Wang, Shadi Pakatchi, Laurent Levy, Charles Liebow, Linda J. Krebs, Paras N. Prasad, Manjari Lal, Earl J. Bergey, Kyoung-Soo Kim
Publikováno v:
Biomedical Microdevices. 4:293-299
Major advances in nanotechnology and cancer biology have occurred throughout the last 30 years. The concept of “magnetic nanoclinic” demonstrated here, combines these advances in cancer and nanotechnology forming the basis for a new generation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c74038a2620e980fed41d1e16eebb45
https://doi.org/10.1023/a:1020906307053
https://doi.org/10.1023/a:1020906307053
Autor:
Yvette K. Wild, Trisha M. Shattuck, Jessica Costa, Kirsten Saucier, Andrew Arnold, Sanjay M. Mallya, James A. Gallagher, Linda J. Krebs
Publikováno v:
Handbook of Parathyroid Diseases ISBN: 9781461421634
The molecular pathogenesis of primary hyperparathyroidism has recently been elucidated to a great extent, but many questions remain. While the molecular genetics of parathyroid disease have notable specific features, the general principles of parathy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7df71fdd24c2eeaf9fdc82746b5feeba
https://doi.org/10.1007/978-1-4614-2164-1_16
https://doi.org/10.1007/978-1-4614-2164-1_16
Publikováno v:
The Journal of clinical endocrinology and metabolism. 90(9)
Mutations of HRPT2 are frequent in sporadic parathyroid carcinomas and central to their pathogenesis. However, the potential diagnostic utility of HRPT2 mutation status to distinguish between parathyroid carcinoma and adenoma hinges on the frequency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4380c42e51d363fceb2a59eadea596
https://pubmed.ncbi.nlm.nih.gov/16148350
https://pubmed.ncbi.nlm.nih.gov/16148350
Autor:
Linda J, Krebs
Publikováno v:
Current opinion in investigational drugs (London, England : 2000). 5(10)
The calcium-sensing receptor (CaSR) is a key regulator of parathyroid hormone (PTH) secretion and parathyroid proliferation. This review discusses the role of the CaSR in hyperparathyroidism (HPT), and the exploitation of the CaSR as a therapeutic ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::597890cd32fac337ddbe6971320623f6
https://pubmed.ncbi.nlm.nih.gov/15535429
https://pubmed.ncbi.nlm.nih.gov/15535429
Bombesin and epidermal growth factor potentiate the effect of cytotoxic LH-RH analog AN-152 in vitro
Autor:
Paras N. Prasad, Atilla Nagy, Andrew V. Schally, Xiaopeng Wang, Linda J. Krebs, Charles Liebow
Publikováno v:
International Journal of Oncology.
The conjugation of doxorubicin with [D-Lys6] Luteinizing Hormone-Releasing Hormone (LH-RH), yields AN-152, a cytotoxic analog that can be targeted to tumor cells expressing LH-RH receptors. This conjugate is more potent against LH-RH receptor positiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::092e1fc0b3e070784e6669efeb801388
https://doi.org/10.3892/ijo.21.6.1325
https://doi.org/10.3892/ijo.21.6.1325
Bombesin and epidermal growth factor potentiate the effect of cytotoxic LH-RH analog AN-152 in vitro
Autor:
Linda J, Krebs, Xiaopeng, Wang, Atilla, Nagy, Andrew V, Schally, Paras N, Prasad, Charles, Liebow
Publikováno v:
International journal of oncology. 21(6)
The conjugation of doxorubicin with [D-Lys6] Luteinizing Hormone-Releasing Hormone (LH-RH), yields AN-152, a cytotoxic analog that can be targeted to tumor cells expressing LH-RH receptors. This conjugate is more potent against LH-RH receptor positiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6a83b46507c71ae12dcb54ed69b6791
https://pubmed.ncbi.nlm.nih.gov/12429984
https://pubmed.ncbi.nlm.nih.gov/12429984
Autor:
Andrew, Arnold, Trisha M, Shattuck, Sanjay M, Mallya, Linda J, Krebs, Jessica, Costa, James, Gallagher, Yvette, Wild, Kirsten, Saucier
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 17
This article will primarily focus on the molecular pathogenesis of common, sporadic (nonfamilial) parathyroid adenomas; two genes currently have established roles in the development of these tumors. The cyclin D1/PRAD1 gene was identified as a clonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ecbbf230565e5eeeee15897e37dda4a
https://pubmed.ncbi.nlm.nih.gov/12412775
https://pubmed.ncbi.nlm.nih.gov/12412775
Autor:
Paras N. Prasad, Linda J. Krebs, Atilla Nagy, Charles Liebow, Xiaopeng Wang, Andrew V. Schally
Publikováno v:
Oral oncology. 38(7)
A doxorubicin and [D-Lys(6)]Luteinizing Hormone-Releasing Hormone (LH-RH) conjugate, AN-152, was designed to target LH-RH receptor positive cells. AN-152 is more potent against a specific group of cancers than doxorubicin and has less peripheral toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75871b45ef9966d2adbf4171a6c48f1
https://pubmed.ncbi.nlm.nih.gov/12353491
https://pubmed.ncbi.nlm.nih.gov/12353491
Autor:
Paras N. Prasad, Earl J. Bergey, Linda J. Krebs, Rakesh Kapoor, Charles Liebow, Christopher S. Friend, Xiaopeng Wang, Haridas E. Pudavar
Publikováno v:
SPIE Proceedings.
Imaging in biological systems has become one of the most relied upon tools in the study of human disease. Two-photon excitation methodology in laser scanning microscopy has resulted in 3D-imaging capability not easily achieved in one- photon systems.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3829ef18e7681b5d6487c33b0662392
https://doi.org/10.1117/12.424539
https://doi.org/10.1117/12.424539