Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Linda J. Kopaciewicz"'
Autor:
A. Nichols, J. Samanen, Linda J. Kopaciewicz, Barbara L. Storer, Raul R. Calvo, Janice A. Vasko, Fadia E. Ali, Richard E. Valocik, Todd Romoff
Publikováno v:
Thrombosis research. 75(2)
The properties of SK&F 106760 [N alpha-acetyl-cyclo(S,S)-cysteinyl-N alpha-methyl-arginyl-glycyl-aspartyl-penicillamine-amide] as a GPIIb/IIIa antagonist have been studied in vitro and compared with those of the parent molecule, Ac-RGDS-NH2. Ac-RGDS-
Publikováno v:
Journal of pharmacological methods. 25(4)
Myocardial infarction studies in pigs have been complicated by the use of antiarrhythmic drugs or the high incidence of ventricular fibrillation. We report on a new model of experimental myocardial infarction in thiamylal-anesthetized Yucatan minipig
Publikováno v:
Thrombosis Research. 19:119-124
Homogenates of washed canine platelets possessed an adenylate cyclase system that was potently activated by prostaglandin (PG) E 1 and to a lesser extent by PGE 2 , A 2 and F 2a . The effect of the PGs on adenylate cyclase were not augmented by the G
Autor:
G A Kopia, Linda J. Kopaciewicz, Robert R. Ruffolo, Kei-Lai L. Fong, Kathleen Boyle, Carl S. Crysler
Publikováno v:
Journal of Cardiovascular Pharmacology. 12:308-316
The thrombolytic dose-response effectiveness and pharmacokinetics of tissue-type plasminogen activator (rt-PA) was evaluated in anesthetized, open-chest dogs instrumented for the measurement of systemic hemodynamics. Intracoronary thrombi were formed