Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Linda J. Hazell"'
Publikováno v:
Free Radical Biology and Medicine. 31:1254-1262
The oxidative modification of low-density lipoprotein (LDL) is thought to contribute to atherogenesis, and there is evidence that oxidants derived from myeloperoxidase (MPO) contribute to such oxidative damage. Using human iliac arteries we investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723975b46fbe74c71db002ea4928bf85
https://doi.org/10.1016/s0891-5849(01)00717-1
https://doi.org/10.1016/s0891-5849(01)00717-1
Publikováno v:
Journal of Clinical Investigation. 97:1535-1544
Oxidation of LDL may contribute to atherogenesis, though the nature of the in vivo oxidant(s) remains obscure. Myeloperoxidase, the enzyme responsible for hypochlorous acid/hypochlorite (HOCl) production in vivo, is present in active form in human at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee6cbe41239f38c57a53fe99de03f0a
https://doi.org/10.1172/jci118576
https://doi.org/10.1172/jci118576
Publikováno v:
Biochemical Journal. 302:297-304
Peroxidation of low-density lipoprotein (LDL) lipid is generally thought to represent the initial step in a series of modification reactions that ultimately transform the protein moiety of the lipoprotein into a form recognized by receptors different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a94862d733adcf999f0da9ec1cadae
https://doi.org/10.1042/bj3020297
https://doi.org/10.1042/bj3020297
Publikováno v:
Clinicalexperimental optometry. 85(2)
BACKGROUND Oxidative damage to lens proteins is associated with human age-related nuclear cataract and H2O2 has been implicated. As hypochlorous acid (HOCl) can be formed from chloride ions and H2O2 and many of the protein modifications observed in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4a52e0e39fe6faad28693bf6f61651
https://pubmed.ncbi.nlm.nih.gov/11952405
https://pubmed.ncbi.nlm.nih.gov/11952405
Autor:
Linda J. Hazell, Roland Stocker
Publikováno v:
FEBS letters. 414(3)
The amount of alpha-tocopherol (alpha-TOH) can dramatically alter the extent of radical-induced oxidation of low density lipoprotein (LDL) lipids, a process generally thought to be important in atherogenesis. However, LDL with atherogenic features ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30d6ca9b0c6344c8c99850b65b2f85e
https://pubmed.ncbi.nlm.nih.gov/9323031
https://pubmed.ncbi.nlm.nih.gov/9323031
Autor:
Roland Stocker, Linda J. Hazell, Hermann Esterbauer, Wolfgang Sattler, Ernst Malle, Georg Waeg
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 15(7)
Abstract Oxidation of LDL is thought to contribute to the early stages of atherogenesis. Because myeloperoxidase is present in atherosclerotic lesions and can produce the strong oxidant hypochlorous acid (HOCl), which converts LDL into its high-uptak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df3b43a9c20a9c78740a2d3a3125a44
https://pubmed.ncbi.nlm.nih.gov/7541296
https://pubmed.ncbi.nlm.nih.gov/7541296
Autor:
Roland Stocker, Linda J. Hazell
Oxidation of low-density lipoprotein (LDL) lipid is thought to represent the initial step in a series of oxidative modification reactions that ultimately transform this lipoprotein into an atherogenic high-uptake form that can cause lipid accumulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc0f309dc1c38b98f9cfaecce33d706
https://europepmc.org/articles/PMC1132397/
https://europepmc.org/articles/PMC1132397/
