Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Linda I. Anderson"'
Publikováno v:
Neuroscience. 130:369-382
Estrogen (E) can function as a neuroprotectant of the nigrostriatal dopaminergic (NSDA) system against methamphetamine (MA) neurotoxicity in female, but not male, mice. In the present report we examined whether the organizational effects of gonadal s
Publikováno v:
Neurotoxicology and Teratology. 24:267-273
Methamphetamine (MA)-related deaths and nigrostriatal dopaminergic (NSDA) neurotoxicity are greater in males. The exact basis for this gender difference is not known, but data, which show that estrogen (E) can function as a protectant of both the car
Publikováno v:
Journal of Neuroendocrinology. 13:618-624
It has been demonstrated that the nigrostriatal dopaminergic system of male mice is more sensitive to the neurotoxic effects of methamphetamine (MA). The basis for this difference can be related to oestrogen, which has the capacity to function as a n
Publikováno v:
Experimental Neurology. 170:121-128
Deletion of a single copy of the BDNF gene has been shown to affect the nigrostriatal dopaminergic system of young adult BDNF mice. In the present report we evaluated various indices of nigrostriatal dopaminergic function between 9-month-old wild-typ
Publikováno v:
Journal of Neuroendocrinology. 11:801-803
In the present report adult female rats were ovariectomized (OVX) and assigned to one of four treatment conditions. Treatments consisted of administering pellets containing 17beta-oestradiol (E), tamoxifen (TMX), a combination of TMX and E or no furt
Autor:
Dean E. Dluzen, Linda I. Anderson
Publikováno v:
Neuroscience Letters. 230:140-142
In the present experiment we examined the effects of an in vitro infusion of nicotine (10 μM) upon dopamine release from superfused striatum of castrated male and female rats treated or not treated with estrogen. Estrogen exerted bidirectional effec
Autor:
Janet L. Mcdermott, Jeffrey N. Joyce, Jon M. Walro, Tracy Osredkar, J. Kucera, Dean E. Dluzen, Linda I. Anderson
Publikováno v:
Neuroscience. 128(1)
The effects of a deletion for the brain derived neurotrophic factor (BDNF) allele (+/- BDNF) upon age-related changes in nigrostriatal dopaminergic (NSDA) function were assessed. Behavioral (beam crossing and spontaneous activity) and neurochemical (
Publikováno v:
Neurotoxicity research. 3(3)
The capacity for 17-alpha and 17-Beta estradiol to modulate MPTP-induced neurotoxicity of the nigrostriatal dopaminergic system and potential antagonism of this modulation by the anti-estrogen, tamoxifen, were evaluated. Treatment of retired breeder
Publikováno v:
Neuroendocrinology. 77(4)
In this report female and male CD-1 mice were treated with a neurotoxic regimen of methamphetamine (MA) to compare gender differences in striatal dopamine depletion and concordant changes in mRNA markers of the transforming growth factor-β injury re
Publikováno v:
Neurochemistry international. 32(3)
Tamoxifen (10 pg/ml) was infused directly into superfused striatal tissue fragments of ovariectomized rats for a 50 min period. Immediately following the termination of tamoxifen there was a significant increase in dopamine output compared with non-i