Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Linda Hsie"'
Autor:
Mark J. Magbanua, Laura Huppert, Janifer Cruz, Jackson Goudreau, Shaopu Zhou, Keyi Yin, Pavel Stejskal, Ryan Carelli, Julie Kim, Linda Hsie, Maggie Wang, Zhouyang Lian, Michael Phelan, Manisha Ray, Chassidy Johnson, Amy L. Delson, Ron Balassanian, Jennifer Rosenbluth, Laura van't Veer, Michelle Melisko, Hope S. Rugo, Mahyar Salek, Maddison Masaeli, Hani Goodarzi
Publikováno v:
Cancer Research. 83:LB170-LB170
Patients with metastatic breast cancer (MBC) can develop malignant effusions (MEs) when excess fluid and tumor cells accumulate in the pleural or peritoneal space. MEs are associated with significant morbidity and mortality. Tropism of tumor cells in
Autor:
Marc K. Halushka, Naiping Shen, Aravinda Chakravarti, Jian-Bing Fan, Kimberly Bentley, Linda Hsie, Richard S. Cooper, Robert J. Lipshutz, Alan B. Weder
Publikováno v:
Nature Genetics. 22:239-247
Sequence variation in human genes is largely confined to single-nucleotide polymorphisms (SNPs) and is valuable in tests of association with common diseases and pharmacogenetic traits. We performed a systematic and comprehensive survey of molecular v
Autor:
Jian-Bing Fan, R. A. Mayer, Eric S. Lander, David G. Wang, Lawrence C. Brody, Keith Edgemon, Bryan K. Sun, Oliver A. Ryder, Li Jin, Christiane M. Robbins, G. Ghandour, Linda Hsie, Frank H. Collins, Robert J. Lipshutz, Joseph G. Hacia, Stephen P. A. Fodor
Publikováno v:
Nature Genetics. 22:164-167
Here we report the application of high-density oligonucleotide array (DNA chip)-based analysis to determine the distant history of single nucleotide polymorphisms (SNPs) in current human populations. We analysed orthologues for 397 human SNP sites (i
Autor:
Eric S. Lander, Nancy Perkins, Thomas J. Hudson, Linda Hsie, Lincoln Stein, Robert J. Lipshutz, Chad Nusbaum, Ellen Winchester, Michael P. Mittmann, Ron Sapolsky, Jessica B. Spencer, Leonid Kruglyak, Steve Rozen, Elizabeth M. Robinson, Naiping Shen, Mark S. Chee, John D. Rioux, Ghassan Ghandour, Thodoros Topaloglou, Earl Hubbell, Dan Kilburn, Macdonald S. Morris, Jian-Bing Fan, Chia-Jen Siao, Peter M. Young, Anthony Berno, David G. Wang
Publikováno v:
Science. 280:1077-1082
Single-nucleotide polymorphisms (SNPs) are the most frequent type of variation in the human genome, and they provide powerful tools for a variety of medical genetic studies. In a large-scale survey for SNPs, 2.3 megabases of human genomic DNA was exa
Autor:
Jean-Philippe Laviolette, Elisabeth Robinson, Thomas J. Hudson, Rob Lipshutz, Kerstin Lindblad-Toh, Naiping Shen, Jian-Bing Fan, Dominik Gehl, David Wang, Damian Labuda, Linda Hsie
Publikováno v:
Genomics. 80(3)
We have analyzed human genomic diversity in 32 individuals representing four continental populations of Homo sapiens in the context of four ape species. We used DNA resequencing chips covering 898 expressed sequence tags (ESTs), corresponding to 109
Autor:
Giulia C. Kennedy, Linda Hsie, Lori Hoffner, Pui-Yan Kwok, Patricia Taillon-Miller, David G. Mutch, Thomas B. Ryder, Urvashi Surti, Jian-Bing Fan
Publikováno v:
Genomics. 79(1)
Complete hydatidiform moles (CHMs) are diploid tumors that result from fertilization of an empty ovum by a haploid 23,X sperm. In most cases, the resulting duplication of the genome gives rise to a 46,XX genotype and is thought to be androgenetic in
Autor:
Ghassan Ghandour, Anthony Berno, Ronald J. Sapolsky, Linda Hsie, Michael Mittmann, Jian-Bing Fan
Publikováno v:
Genetic analysis : biomolecular engineering. 14(5-6)
A highly reliable and efficient technology has been developed for high-throughput DNA polymorphism screening and large-scale genotyping. Photolithographic synthesis has been used to generate miniaturized, high-density oligonucleotide arrays. Dedicate