Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Linda Hermus"'
An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage.
Autor:
Rajaie Namas, Ali Ghuma, Andres Torres, Patricio Polanco, Hernando Gomez, Derek Barclay, Lisa Gordon, Sven Zenker, Hyung Kook Kim, Linda Hermus, Ruben Zamora, Matthew R Rosengart, Gilles Clermont, Andrew Peitzman, Timothy R Billiar, Juan Ochoa, Michael R Pinsky, Juan Carlos Puyana, Yoram Vodovotz
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8406 (2009)
BACKGROUND:Trauma/hemorrhagic shock (T/HS) results in cytokine-mediated acute inflammation that is generally considered detrimental. METHODOLOGY/PRINCIPAL FINDINGS:Paradoxically, plasma levels of the early inflammatory cytokine TNF-alpha (but not IL-
Externí odkaz:
https://doaj.org/article/c536708d11474bfc8381dae7a923e8be
Autor:
Ruben Zamora, Thierry Clermont, Cristina Megas, Mallikarjuna R. Metukuri, Chase Gladstone, Mitchell P. Fink, Rajaie Namas, Timothy R. Billiar, Gregory M. Constantine, Rami A. Namas, Nabil Azhar, Linda Hermus, Yoram Vodovotz
Publikováno v:
Journal of Biological Chemistry. 287:31003-31014
Extracellular β-nicotinamide adenine dinucleotide (NAD+) is anti-inflammatory. We hypothesized that NAD+ would modulate the anti-inflammatory cytokine Transforming Growth Factor (TGF)-β1. Indeed, NAD+ led to increases in both active and latent cell
Autor:
Clark J. Zeebregts, Linda Hermus, Joost H. N. Schuitemaker, Jan Cees Breek, Esther de Boef, Riemer H. J. A. Slart, René A. Tio
Publikováno v:
Clinical biochemistry, 44(16), 1292-1298. PERGAMON-ELSEVIER SCIENCE LTD
Objectives: Serum biomarkers representing inflammatory activity in vulnerable carotid plaques may be used to identify high-risk patients for cerebral ischemic events. We aimed to analyze the relationship between concentrations of four novel biomarker
Publikováno v:
ATHEROSCLEROSIS. 213(1):21-29
Treatment of carotid artery stenosis by endarterectomy or stenting can significantly reduce stroke risk, but is also associated with surgery related mortality and morbidity. At present it is neither possible to assess whether a carotid plaque will be
Autor:
B. M. Wallis de Vries, Clark J. Zeebregts, I. F. J. Tielliu, van den Johannes Dungen, Linda Hermus
Publikováno v:
Acta Chirurgica Belgica. 110:159-164
Imaging plays a key role in the selection of patients for carotid artery surgery. Indication for carotid endarterectomy or stenting is based on symptomatology and degree of stenosis as determined by angiography, duplex ultrasonography or computed tom
Autor:
Linda Hermus, Rajaie Namas, Yoram Vodovotz, Gilles Clermont, Hernando Gomez, Juan Carlos Puyana, J. Mesquida, Michael R. Pinsky, Hyung Kook Kim, Andres Torres, Sven Zenker, Patricio M. Polanco
Publikováno v:
The Journal of surgical research. 178(1)
The causes of cardiovascular collapse (CC) during hemorrhagic shock (HS) are unknown. We hypothesized that vascular tone loss characterizes CC, and that arterial pulse pressure/stroke volume index ratio or vascular tone index (VTI) would identify CC.
Publikováno v:
Surgical technology international. 20
Stroke is the third most common cause of mortality, and carotid artery stenosis causes 8% to 29% of all ischemic strokes. Best medical treatment forms the basis of carotid stenosis treatment, and carotid endarterectomy (CEA) has an additional benefic
Autor:
Juan Carlos Puyana, Derek Barclay, Andres Torres, Michael R. Pinsky, Gilles Clermont, Rajaie Namas, Patricio M. Polanco, Juan B. Ochoa, Lisa Gordon, Hernando Gomez, Hyung Kook Kim, Linda Hermus, Yoram Vodovotz, Sven Zenker, Andrew B. Peitzman, Matthew R. Rosengart, Ali Ghuma, Timothy R. Billiar, Ruben Zamora
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8406 (2009)
PLoS ONE
PLoS ONE
BACKGROUND:Trauma/hemorrhagic shock (T/HS) results in cytokine-mediated acute inflammation that is generally considered detrimental. METHODOLOGY/PRINCIPAL FINDINGS:Paradoxically, plasma levels of the early inflammatory cytokine TNF-alpha (but not IL-
Publikováno v:
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 39(2)
Treatment of carotid artery stenosis by endarterectomy or stenting can significantly reduce stroke risk. In clinical practice, indication for surgery or stenting is primarily based on the degree of stenosis, but there is growing awareness that pathop
Autor:
Ruben Zamora, Rajaie Namas, Chase Gladstone, Thierry Clermont, Linda Hermus, Mallikarjuna R. Metukuri, Bahiyya Jefferson, Derek Barclay, Yoram Vodovotz, Timothy R. Billiar
Publikováno v:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 17(4)
The inducible nitric oxide (NO) synthase and the cytokine transforming growth factor-beta1 (TGF-beta1), both central modulators of wound healing, interact reciprocally: TGF-beta1 generally suppresses iNOS expression, while NO can induce and activate