Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Linda H. Schneider"'
Autor:
James Gibbs, Randall B. Murphy, James M. Chen, Linda H. Schneider, Gerard P. Smith, Daryll C. Dykes, Matthew R. Pincus, Margery C. Beinfeld
Publikováno v:
Journal of Protein Chemistry. 11:723-729
Prior calculations based on ECEPP (Empirical Conformational Energies for Peptides Program) of the low energy minima for cholecystokinin (CCK) and Met-enkephalin have demonstrated that significant structural features of these two peptides are identica
Publikováno v:
Peptides. 13:77-81
Cholecystokinin COOH-terminal octapeptide (CCK-8) produces a satiating effect in the rat and other animals upon peripheral administration. Although it has been demonstrated that the receptors which mediate this action are located in the periphery and
Publikováno v:
Brain research. 550(1)
Selective antagonists of either the D1 receptor (SCH 23390) or of the D2 receptor (raclopride) produce a dose-related inhibition of sucrose sham feeding in the rat. We investigated the effect of combined treatments with these antagonists on sucrose s
Publikováno v:
European journal of pharmacology. 186(1)
Raclopride, a dopamine D2 antagonist, decreases the intake of sucrose solutions during sham feeding tests and of water during sham drinking tests in rats. To determine whether the reduced intake of sucrose by raclopride was due to a decrease in the p
Autor:
Randall B. Murphy, J. M. Howard, Jerry D. Gardner, M. Trampota, S. W. Jones, Linda H. Schneider, Robert T. Jensen
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 249:G214-G220
Proglumide [N-(benzoyl)-L-glutamic acid-1-di-n-propylamide] is a specific cholecystokinin receptor antagonist. In the present study we synthesized various analogues of proglumide and used pancreatic acini from guinea pig pancreas to examine the abili
Publikováno v:
Neuroscience Letters. 33:281-284
A highly significant endogenous lateral asymmetry in striatal dopamine (D2) receptors was found utilizing the binding of [3H]spiroperidol (0.6 nM) to homogenates prepared from the left and the right striata of male rats individually assayed. The mean
Publikováno v:
Annals of the New York Academy of Sciences. 537:534-537
Autor:
Gerard P. Smith, Linda H. Schneider
Publikováno v:
Annals of the New York Academy of Sciences. 537:254-261
These experiments are the first to correlate a specific stimulus of eating--the orosensory stimulation by sucrose--to mesolimbic dopaminergic activity. The pharmacological results and the increase in hypothalamic DOPAC/DA are convergent evidence for
Publikováno v:
Peptides. 9:207-214
The reduction in food intake produced by exogenous CCK-8 (8 μg·kg −1 , IP) in 18 hr food-deprived rats was significantly reversed by either of two proglumide analogues at doses of 0.44 and 4.4 μM·kg −1 . The two glutamic acid derivatives test
Publikováno v:
Annals of the New York Academy of Sciences. 448:633-635