Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Linda H. Fossom"'
Autor:
Pei-I Chu, Peter P. Fu, Ramesh Sood, Tao Chen, Martha M. Moore, Daniel J. Mans, Linda H. Fossom, Jian Yan, Fanxue Meng, Yan Li
Publikováno v:
Toxicology and Applied Pharmacology. 270:158-163
Impurities are present in any drug substance or drug product. They can be process-related impurities that are not completely removed during purification or are formed due to the degradation of the drug substance over the product shelf-life. Unlike th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5309509d780293f4eff79d73f00029d6
https://doi.org/10.1016/j.taap.2013.04.012
https://doi.org/10.1016/j.taap.2013.04.012
Publikováno v:
Molecular Pharmacology. 56:1207-1218
1-Aminocyclopropanecarboxylic acid (ACPC) has been shown to protect against neuronal cell death after ischemic insult in vivo. Such results can be correlated with in vitro assays in which ACPC protected neurons against glutamate-induced neurotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062b48f68ec9d46c8aa3a2dcaba0925f
https://doi.org/10.1124/mol.56.6.1207
https://doi.org/10.1124/mol.56.6.1207
Publikováno v:
European Journal of Pharmacology. 356:255-260
Sustained (20 h) exposure to the glycine partial agonist 1-aminocyclopropanecarboxylic acid (ACPC) significantly reduced N-methyl- d -aspartate (NMDA)-induced neurotoxicity in cultured spinal cord neurons when the NMDA (25 and 100 μM) was added to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6178f25228d343360d098e8eccf915
https://doi.org/10.1016/s0014-2999(98)00515-9
https://doi.org/10.1016/s0014-2999(98)00515-9
Autor:
Anthony S. Basile, Elena Koustova, Michael A. Rogawski, Peter N.R. Usherwood, Linda H. Fossom, N. Bradley Keele, Yoshitatsu Sei, Mei Ling Wei
Publikováno v:
The Journal of clinical investigation. 107(6)
Autoantibodies to alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors may contribute to chronic hyperexcitability syndromes and neurodegeneration, but their origin is unclear. We examined LP-BM5 murine leukemia virus-infected mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acd0adc39c4ef5aad5a4a61aac3ce22
https://pubmed.ncbi.nlm.nih.gov/11254673
https://pubmed.ncbi.nlm.nih.gov/11254673
Publikováno v:
Journal of molecular neuroscience : MN. 10(3)
Chronic administration of antidepressants produces region-specific adaptive changes in the radioligand binding properties of N-methyl-D-aspartate (NMDA) receptors. We hypothesized that this effect of chronic antidepressant administration was owing to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d2e28db4f531c04886fcb4d2d866af
https://pubmed.ncbi.nlm.nih.gov/9770644
https://pubmed.ncbi.nlm.nih.gov/9770644
Publikováno v:
Neuroscience letters. 241(2-3)
The effects of quinolinic acid (QUIN) on glutamate-induced excitotoxicity were examined in primary cultures of rat cerebellar granule neurons. Exposing these neurons to QUIN (< or =2.5 mM) in the presence of glucose and Mg2+ had no effect on their vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34ff0c982edce74982b8d3cb16a6beb
https://pubmed.ncbi.nlm.nih.gov/9507950
https://pubmed.ncbi.nlm.nih.gov/9507950
Autor:
Li-Ming Zhou, Gyorgyi I. Szendrei, Linda H. Fossom, Maria-Luisa Maccecchini, Laszlo Otvos, Phil Skolnick
Publikováno v:
Journal of neurochemistry. 66(2)
Conantokin-G (con-G) is a 17-amino-acid polypeptide that acts as an N-methyl-D-aspartate (NMDA) antagonist. This action has been attributed to a specific but noncompetitive inhibition of the positive modulatory effects of polyamines at NMDA receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012382bda09bd4f6670159ef8fda1c48
https://pubmed.ncbi.nlm.nih.gov/8592132
https://pubmed.ncbi.nlm.nih.gov/8592132
Publikováno v:
Neurological research. 17(4)
1-Aminocyclopropanecarboxylic acid is a high affinity ligand with partial agonist properties at strychnine-insensitive glycine sites associated with the N-methyl-D-aspartate subtype of glutamate receptors. Since occupation of these sites appears requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b4dc4f0bf455ada69da640e3addc79
https://pubmed.ncbi.nlm.nih.gov/7477740
https://pubmed.ncbi.nlm.nih.gov/7477740
Autor:
Anthony S. Basile, Rick C.S. Lin, Markus Borner, Linda H. Fossom, Yoshitatsu Sei, Dag K.J.E. Von Lubitz, Phil Skolnick
Publikováno v:
Neuroscience letters. 171(1-2)
Internucleosomal DNA fragmentation, the characteristics feature of programmed cell death, was demonstrated in gerbil hippocampus following 10 min of forebrain ischemia. Quantitative analysis revealed the presence of DNA fragments as early as 12 h aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac950ae1eef5fe5d2ec519d8bf7c82c
https://pubmed.ncbi.nlm.nih.gov/8084486
https://pubmed.ncbi.nlm.nih.gov/8084486
Autor:
Linda H. Fossom, Phil Skolnick
Publikováno v:
Annals of the New York Academy of Sciences. 765:320-321
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f410b07feb408a87a1d0056be5f332b0
https://doi.org/10.1111/j.1749-6632.1995.tb16601.x
https://doi.org/10.1111/j.1749-6632.1995.tb16601.x