Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Linda Gijzen"'
Autor:
Fiona Chapman, Luuk de Haan, Linda Gijzen, Wouter Strijker, Edgar Trelles Sticken, Sarah Jean Pour, Roman Wieczorek, Florian Haberstroh, Sandra Otte, Thomas Nahde, Liam Simms, Matthew Stevenson
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
BackgroundSmoking cigarettes is a cause of serious diseases in smokers, including cardiovascular disease. Through a pathway of endothelial dysfunction, lipid infiltration, macrophage recruitment and vascular remodeling, atherosclerosis is fundamental
Externí odkaz:
https://doaj.org/article/0d419d3534074626a058c1b663677538
Autor:
Linda Gijzen, Kouichi Yoshinari, Niels Ouwerkerk, Kei Motonaga, Marleen Bokkers, Yuki Hagiwara, Remko van Vught, Harumi Kumagai, Tomokazu Tajiri, Rumaisha Annida, Yoshifumi Katakawa
Publikováno v:
Journal of Pharmaceutical Sciences. 111:214-224
The aim of this study was to develop an in vitro drug permeability methodology which mimics the gastrointestinal environment more accurately than conventional 2D methodologies through a three-dimensional (3D) Caco-2 tubules using a microphysiological
Autor:
Arnaud Nicolas, Carola M. E. Ammerlaan, Linda Gijzen, Marianne K. Vormann, Paul Vulto, Maarten B. Rookmaaker, Frans Schutgens, Dorota Kurek, Hans Clevers, Fjodor A. Yousef Yengej, Henriëtte L. Lanz, Marianne C. Verhaar
Publikováno v:
Nature Protocols, 16(4), 2023-2050. Nature Publishing Group
Advanced in vitro kidney models are of great importance to the study of renal physiology and disease. Kidney tubuloids can be established from primary cells derived from adult kidney tissue or urine. Tubuloids are three-dimensional multicellular stru
Autor:
Remko van Vught, Giuseppe Lo Sasso, Manuel C. Peitsch, Jos Joore, Linda Gijzen, Dorota Kurek, Henriëtte Leonore Lanz, Arnaud Nicolas, Elisa Raineri, Diego Marescotti, Julia Hoeng, Paul Vulto, Diego Guerrera
Publikováno v:
Slas Technology
Development of efficient drugs and therapies for the treatment of inflammatory conditions in the intestine is often hampered by the lack of reliable, robust, and high-throughput in vitro and in vivo models. Current models generally fail to recapitula
Autor:
Kazuhiro Tetsuka, Laura M Tool, Fumiko Kiyonaga, Marianne K. Vormann, Akira Fujimori, Masato Ohbuchi, Paul Vulto, Thomas Hankemeier, Takayuki Goto, Remko van Vught, Linda Gijzen, Henriëtte L. Lanz, Tetsuhiro Kawabe
Publikováno v:
Kidney360
Background: Renal ischemia/reperfusion injury (rIRI) is one of the major causes of acute kidney injury (AKI). While animal models are suitable for investigating systemic symptoms of AKI they are limited in translatability. Human in vitro models are c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13dda44bc10390b4a5e7a95719ab5001
https://europepmc.org/articles/PMC8967632/
https://europepmc.org/articles/PMC8967632/
Autor:
Linda, Gijzen, Fjodor A, Yousef Yengej, Frans, Schutgens, Marianne K, Vormann, Carola M E, Ammerlaan, Arnaud, Nicolas, Dorota, Kurek, Paul, Vulto, Maarten B, Rookmaaker, Henriette L, Lanz, Marianne C, Verhaar, Hans, Clevers
Publikováno v:
Nature protocols. 16(4)
Advanced in vitro kidney models are of great importance to the study of renal physiology and disease. Kidney tubuloids can be established from primary cells derived from adult kidney tissue or urine. Tubuloids are three-dimensional multicellular stru
Autor:
Arnaud Nicolas, Henriëtte L. Lanz, Dorota Kurek, Julia Hoeng, Diego Marescotti, Paul Vulto, Diego Guerrera, Manuel C. Peitsch, R. Van Vught, E Raineri, Jos Joore, G Lo Sasso, Linda Gijzen, Elena Naumovska
Publikováno v:
Journal of Crohn's and Colitis. 14:S132-S133
Background One of the major functions of the human intestine is to provide a protective epithelial barrier between the body and digestive environment. Additionally, the interplay of commensal microbes of the gut microbiome with the gut tissue and hos
Autor:
Henriëtte L. Lanz, Sebastiaan Johannes Trietsch, Anthony D. Saleh, Jos Joore, Linda Gijzen, Paul Vulto, Marianne K. Vormann, Remko van Vught
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:S55
Autor:
Rosalinde Masereeuw, Laura Suter-Dick, Martijn J. Wilmer, Marianne K. Vormann, Henriëtte L. Lanz, Simon Hutter, Jos Joore, Linda Gijzen, Sebastiaan Johannes Trietsch, Jelle Vriend
Publikováno v:
Toxicology Letters. 295:S68
Autor:
Anthony D. Saleh, Devon Anderson, Jos Joore, Marianne K. Vormann, Linda Gijzen, Henriëtte L. Lanz, Paul Vulto, Toni Steiner, Dave Thompson
Publikováno v:
Drug Metabolism and Pharmacokinetics. 33:S70