Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Linda Garthwaite"'
Autor:
Cristan Herbert, Jessica S. Siegle, Alexander M. Shadie, Stina Nikolaysen, Linda Garthwaite, Nicole G. Hansbro, Paul S. Foster, Rakesh K. Kumar
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 2, Pp 479-488 (2013)
SUMMARY Childhood exposure to environmental particulates increases the risk of development of asthma. The underlying mechanisms might include oxidant injury to airway epithelial cells (AEC). We investigated the ability of ambient environmental partic
Externí odkaz:
https://doaj.org/article/1191b337f88245718e0dda4328f753f7
Autor:
Yuka Hiroshima, Linda Garthwaite, Kenneth Hsu, Hyouna Yoo, Sang-Ho Park, Carolyn L. Geczy, Rakesh K. Kumar, Cristan Herbert
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Glucocorticoids are commonly used for treating asthma and its exacerbations but have well-recognised adverse effects and are not always effective. Few alternative treatments exist. Using a murine model of an acute exacerbation of asthma, we assessed
Externí odkaz:
https://doaj.org/article/7a5f867692954f259bed4ae63f3442b9
Autor:
Cristan Herbert, Alexander M Shadie, Melissa M Bunting, Nicodemus Tedla, Linda Garthwaite, Araluen Freeman, Hyouna Yoo, Sang-Ho Park, Rakesh K Kumar
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90436 (2014)
There are few alternatives to glucocorticosteroids for treatment of asthma. We assessed the activity of a novel protein drug designated ISU201, the extracellular domain of the human cell surface protein BST2, stabilised by fusion with the Fc region o
Externí odkaz:
https://doaj.org/article/18d5aa64280344d8a69f6cfe60f8dce1
Autor:
Robert G. Parton, Mehdi Mirzaei, Mojdeh Abbasi, Vivek Gupta, Yogita Dheer, Stuart L. Graham, Yuyi You, Veer Bala Gupta, Thiri Zaw, Nitin Chitranshi, Linda Garthwaite
Publikováno v:
Molecular Neurobiology. 57:3759-3784
Retinal ganglion cell degeneration is a characteristic feature of glaucoma, and accordingly, protection of these cells constitutes a major therapeutic objective in the disease. Here, we demonstrate the key influence of caveolin (Cav) in regulating th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf4fe5fe1ad36bdfe8454cc3c1c9ae57
https://doi.org/10.1007/s12035-020-01948-9
https://doi.org/10.1007/s12035-020-01948-9
Autor:
Nitin Chitranshi, Samran Sheriff, Veer Bala Gupta, Mehdi Mirzaei, Angela Godinez, Linda Garthwaite, Kanshika Pushpitha Maha Thananthirige, Rashi Rajput, Vivek Gupta, Stuart L. Graham
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6711bf016a28a50b4b0e384d081f0733
https://doi.org/10.1002/alz.046558
https://doi.org/10.1002/alz.046558
Autor:
Mojdeh, Abbasi, Vivek K, Gupta, Nitin, Chitranshi, Veer B, Gupta, Mehdi, Mirzaei, Yogita, Dheer, Linda, Garthwaite, Thiri, Zaw, Robert G, Parton, Yuyi, You, Stuart L, Graham
Publikováno v:
Molecular neurobiology. 57(9)
Retinal ganglion cell degeneration is a characteristic feature of glaucoma, and accordingly, protection of these cells constitutes a major therapeutic objective in the disease. Here, we demonstrate the key influence of caveolin (Cav) in regulating th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f54a664c7afd441a39eda211d05915c0
https://pubmed.ncbi.nlm.nih.gov/32578008
https://pubmed.ncbi.nlm.nih.gov/32578008
Autor:
Vincent Chiu, Cristan Herbert, Linda Garthwaite, Paul M. Young, Yifan Chen, Kimchi Do, Rakesh K. Kumar, Daniela Traini
Publikováno v:
Clinical Science. 131:499-509
Airway epithelial cells (AEC) exhibit a pro-inflammatory phenotype in patients with allergic asthma. We examined the effect of an allergic cytokine environment on the response of AEC to rhinovirus (RV), the most common trigger of acute exacerbations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9dd2bf748adb9f01533290b353a6ed6
https://doi.org/10.1042/cs20160939
https://doi.org/10.1042/cs20160939
Autor:
Shamila Khan, Linda Garthwaite, Tim C.R. Conibear, Nerida Cole, Emma B.H. Hume, Mark D. P. Willcox
Publikováno v:
Experimental Eye Research. 127:184-189
Staphylococcus aureus is a leading cause of corneal infection. CXC receptor 2 binding chemokines have been implicated in the pathogenesis of Pseudomonas aeruginosa keratitis. The role of this receptor in immune responses during Staphylococcus keratit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3daae592377928b1bd5e6395ee70948
https://doi.org/10.1016/j.exer.2014.07.016
https://doi.org/10.1016/j.exer.2014.07.016
Autor:
Cristan Herbert, Kristy Parsons, Peter A. B. Wark, Rakesh K. Kumar, Martin P. Bucknall, Helen Rutlidge, Linda Garthwaite, Alexander M. Shadie, Brendan Halliburton
Publikováno v:
Respirology. 20:73-79
Background and objective Exposure to airborne particulate matter (PM) may promote development of childhood asthma and trigger acute exacerbations of existing asthma via injury to airway epithelial cells (AEC). Methods We compared the response of AEC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92e0689b5ea69fa6b3ff8ee48758397e
https://doi.org/10.1111/resp.12381
https://doi.org/10.1111/resp.12381
Autor:
Cristan Herbert, Stina Nikolaysen, Jessica S. Siegle, Nicole G. Hansbro, Alexander M. Shadie, Rakesh K. Kumar, Linda Garthwaite, Paul S. Foster
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 6, Iss 2, Pp 479-488 (2013)
Disease Models & Mechanisms, Vol 6, Iss 2, Pp 479-488 (2013)
Summary Childhood exposure to environmental particulates increases the risk of development of asthma. The underlying mechanisms might include oxidant injury to airway epithelial cells (AEC). We investigated the ability of ambient environmental partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7fcc10aa12d19c85650325c16ffb279
http://europepmc.org/articles/PMC3597029
http://europepmc.org/articles/PMC3597029