Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Linda D. Beutel"'
Autor:
Robert O. Dillman, Linda D. Beutel
Publikováno v:
Oncology Issues. 23:22-26
Autor:
Robert O. Dillman, Linda D. Beutel, Shankar K. Nayak, Carol DePriest, Senthamil R. Selvan, Patric M. Schiltz
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 20:373-378
Determination of potency is a challenging problem for patient-specific products derived from autologous cells. For several years, we have been investigating the safety and therapeutic potential of patient- specific vaccines derived from short-term au
Autor:
Robert O. Dillman, Louis A. VanderMolen, Kanoe Allen, Neil M. Barth, Linda D. Beutel, Sherri Chico
Publikováno v:
American Journal of Clinical Oncology. 28:281-288
During 1990-1999, we treated 60 patients with breast cancer who had distant metastases with high-dose chemotherapy and autologous stem cell rescue (HDC) after they had responded to induction chemotherapy. HDC regimens were MiTepa (60 mg/m2 mitoxantro
Autor:
Robert O. Dillman, Neil M. Barth, Linda D. Beutel, Senthamil R. Selvan, Cheryl Peterson, Edward F. McClay, Patric M. Schiltz, Patric Sheehy, Cristina de Leon, Kanoe Allen, Carol DePriest
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 19:658-665
The aim of this study was to investigate the feasibility, safety, and clinical efficacy of patient-specific dendritic cell vaccines in patients with metastatic melanoma. A planned interim analysis was conducted on the first 20 patients.Tumor cell lin
Autor:
Linda D. Beutel, Louis A. VanderMolen, Robert O. Dillman, Cristina de Leon, Carol DePriest, Neil M. Barth, Khosrow Mahdavi, Shankar K. Nayak
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 19:570-580
We previously reported the laboratory methodology for producing patient-specific irradiated autologous tumor-cell products derived from short-term cultured tumor cells from resected renal cell carcinoma, and described preliminary clinical results. In
Phase I/II Trial of Autologous Tumor Cell Line–Derived Vaccines for Recurrent or Metastatic Sarcomas
Autor:
Cheryl Peterson, Linda D. Beutel, Shankar K. Nayak, Senthamil R. Selvan, Robert O. Dillman, Neil M. Barth, Cristina de Leon, Carol DePriest
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 19:581-588
We previously reported the laboratory methodology for producing patient-specific irradiated autologous tumor-cell products derived from short-term cultured tumor cells. We attempted to determine the feasibility, safety, and clinical effects of autolo
Autor:
Linda D. Beutel, Robert O. Dillman, Shankar K. Nayak, Audrey A. O'Connor, Neil M. Barth, B. S. N. Carol Depriest, Cristina de Leon
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 17:51-66
We established short-term cultures of pure tumor cells for use as autologous tumor cell vaccines in an effort to study the effects of patients-specific immunotherapy.Surgically resected fresh tumor was obtained from patients with metastatic cancer. S
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 16:205-211
We tried to establish short-term cultures of autologous tumors from patients with breast carcinoma for potential use as active specific immunotherapy (i.e., autologous vaccine) after resection of primary breast cancer, and/or for the treatment of met
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 15:161-168
We have tried to establish short-term cultures of autologous tumors from patients with renal cell carcinoma that could be used as active specific immunotherapy (i.e., autologous vaccine) in such patients after resection of primary kidney cancer, and/
Publikováno v:
Journal of Immunotherapy. 20:377-386
From 1991 to 1995, we initiated cultures of 94 fresh tumor samples of various histologies in an effort to grow tumor-infiltrating lymphocytes (TIL) using flasks and subsequent expansion in semipermeable bags. The five most prevalent tumor types from