Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Linda Cashion"'
Autor:
Gabor M. Rubanyi, Oliver Ast, Cynthia Gross, Husheng Qian, Linda Cashion, Richard N. Harkins, Maxine Bauzon, Alan R. Brooks, Caralee Schaefer, Paul Szymanski, Ann Orme, Harald Petry, Heather Gibson
Publikováno v:
Journal of Interferon & Cytokine Research. 26:699-705
Recombinant interferon-beta (IFN-beta) protein is used successfully for the treatment of multiple sclerosis (MS). Gene therapy might be an alternative approach to overcome drawbacks occurring with IFN-beta protein therapy. A critical issue in develop
Autor:
Cynthia Gross, Richard N. Harkins, Harald Petry, Perry Liu, Linda Cashion, Toni Rose Hidalgo, Hu Sheng Qian, Paul Szymanski, Alan R. Brooks, Claudia Goldman, Caralee Schaefer, Gabor M. Rubanyi, Peiyin Wang
Publikováno v:
Journal of Interferon & Cytokine Research. 26:449-454
Experimental allergic encephalomyelitis (EAE) is a model of central nervous system (CNS) inflammation that follows immunization with certain CNS antigens. The course and clinical manifestations of EAE are similar to those of multiple sclerosis (MS) i
Autor:
Outi Närvänen, Mikko I. Kettunen, Johanna E. Markkanen, Tuomas T. Rissanen, Linda Cashion, Ismo Vajanto, Gabor M. Rubanyi, Pekka Taipale, Seppo Ylä-Herttuala, Katja Arve, Risto A. Kauppinen, Marcin Gruchała, Suvi Jauhiainen, Juha Rutanen
Publikováno v:
The FASEB Journal. 17:100-102
Previous studies have shown that fibroblast growth factor (FGF)-1, FGF-2, and FGF-5 induce therapeutic angiogenesis. Here, we investigated the potential of FGF-4 for therapeutic neovascularization in comparison to vascular endothelial growth factor (
Autor:
Werner Witt, Linda Cashion, Peter Bringmann, Peter Donner, Berthold Baldus, Wolf-Dieter Schleuning
Publikováno v:
Blood. 79:1213-1217
rDSPA alpha 1 (recombinant Desmodus salivary plasminogen activator alpha 1) is a recombinant protein corresponding to a natural plasminogen activator from the vampire bat Desmodus rotundus. The thrombolytic properties of rDSPA alpha 1 and tissue-type
Autor:
Richard N. Harkins, Kelly Plummer, Oliver Ast, Peter Bringmann, Linda Cashion, Andrzej Citkowicz, Claudia Goldmann, Brent R. Larsen, Harald Petry
Publikováno v:
Analytical biochemistry. 376(2)
This study illustrates the application of asymmetrical flow field-flow fractionation (AF4) and light scattering analysis during the development of a gene delivery vehicle based on virus-like particles (VLPs) derived from the human polyoma JC virus. T
Autor:
Richard N. Harkins, Susan Harvey, Gabor M. Rubanyi, Andrzej Citkowicz, Brent R. Larsen, Linda Cashion, Mary Rose Masikat, Perry Liu, Harald Petry, Hu Sheng Qian, Oliver Ast, Branka Mitrovic
Publikováno v:
Molecular Therapy. 13:S411-S412
The goal of the present study was to explore the tropism of Virus-Like Particles (VLP) originating from the human polyoma JC- virus (JCV) in vitro and in vivo. VLP have been known for several years to be a promising alternative to the existing viral
Autor:
Kathy White, Linda Cashion, Terry Hermiston, Peiyin Wang, Alan R. Brooks, Richard N. Harkins, Hu Sheng Qian, Ann Orme, Paul Szymanski, R. Jude Samulski, Maxine Bauzon, Cecile Chartier, Perry Liu, Gabor M. Rubanyi, Heather Gibson
Publikováno v:
Molecular Therapy. 11:S370-S371
Interferon-|[szlig]| (IFN-|[szlig]|) is an immunoregulatory cytokine that has been approved as a protein therapeutic for multiple sclerosis (MS). Pharmacokinetic studies have shown that IFN-|[szlig]| has an extremely short half-life in the circulatio
Autor:
Cynthia Gross, Linda Cashion, Gabor M. Rubanyi, Harald Petry, Hu Sheng Qian, Paul Szymanski, Alan R. Brooks, Claudia Goldman, Heather Gibson, Caralee Schaefer, Peiyin Wang, Toni Rose Arceo, Richard N. Harkins
Publikováno v:
Molecular Therapy. 11:S371
Experimental Allergic Encephalomyelitis (EAE) is a model of central nervous system (CNS) inflammation that ensues following immunization with certain CNS antigens, for example brain derived proteolipid or myelin basic protein. The course and clinical
Autor:
Andrezj Citkowicz, Harald Petry, Gabor M. Rubanyi, Richard N. Harkins, Linda Cashion, Oliver Ast, Brent R. Larsen
Publikováno v:
Molecular Therapy. 11:S68
Virus-like particles (VLP) have been known for several years to be a promising alternative to the existing viral and non-viral DNA delivery systems. VLPs are self-assembled structures composed only of proteins necessary for capsid formation and DNA p
Autor:
Harald Petry, Hu Sheng Qian, Maxine Bauzon, Peiyin Wang, Jude Samulski, Linda Cashion, Cynthia Gross, Terry Hermiston, Ann Orme, Perry Liu, Gabor M. Rubanyi, Paul Szymanski, Alan R. Brooks, Oliver Ast, Richard N. Harkins
Publikováno v:
Molecular Therapy. 11:S370
Interferon beta (IFN-) has been shown to be an effective drug for patients with multiple sclerosis (MS). However dose-dependent side effects from administration of IFN- protein have limited its therapeutic efficacy and clinical utility. IFN- gene the