Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Linda C. Robinson"'
Autor:
Timothy J. Strovas, Aleen D. Saxton, C. Dirk Keene, Gerard D. Schellenberg, Chris R. Guthrie, Brian C. Kraemer, John Q. Trojanowski, Pamela J. McMillan, Linda C. Robinson, Nicholas M. Kanaan, Murray A. Raskind, Jeanna M. Wheeler, Li-San Wang, Nicole F. Liachko, Elaine R. Peskind, Patricia Szot, Virginia M.-Y. Lee, Thomas D. Bird, Rebecca L. Kow, Alexandre Amlie-Wolf, Ronald Klein
Publikováno v:
Sci Transl Med
Brain lesions composed of pathological tau help to drive neurodegeneration in Alzheimer’s disease (AD) and related tauopathies. Here, we identified the mammalian suppressor of tauopathy 2 (MSUT2) gene as a modifier of susceptibility to tau toxicity
Autor:
Brian C. Kraemer, James B. Leverenz, Pamela J. McMillan, Gerard D. Schellenberg, Murray A. Raskind, Linda C. Robinson
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 70:1006-1019
Proteolytic cleavage of tau at glutamic acid 391 (E391) is linked to the pathogenesis of Alzheimer disease (AD). This C-terminal truncated tau species exists in neurofibrillary tangles and abnormal neurites in the brains of AD patients and may potent
Publikováno v:
Journal of Child and Family Studies. 20:111-119
Using a sample of 248 ninth and tenth grade students at public high schools, we examined adolescents’ perceptions of family connectedness, intrinsic religiosity, and adolescents’ gender in relation to depressed mood and whether intrinsic religios
Autor:
Virginia M.-Y. Lee, Gerard D. Schellenberg, Brian C. Kraemer, John Q. Trojanowski, Theresa Schuck, Jeanna M. Wheeler, Linda C. Robinson
Publikováno v:
Acta Neuropathologica. 119:409-419
Abnormal TDP-43 aggregation is a prominent feature in the neuropathology of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration. Mutations in TARDBP, the gene encoding TDP-43, cause some cases of ALS. The normal function of TDP-
Autor:
Pamela J. McMillan, Parvoneh Poorkaj, James B. Leverenz, Linda C. Robinson, Lynne Greenup, Zana Evstafjeva, Elena Korvatska, Gerard D. Schellenberg, Ian D'Souza
Publikováno v:
The Journal of Comparative Neurology. 511:788-803
Tau is a microtubule-associated protein implicated in neurodegenerative tauopathies. Alternative splicing of the tau gene (MAPT) generates six tau isoforms, distinguishable by the exclusion or inclusion of a repeat region of exon 10, which are referr
Autor:
Jennifer W. McKee-Johnson, Vas P. Demas, Robert S. Silverstein, Joshua X. Gittelman, Timothy D. Hanks, Shing Yan Chiu, Bruce L. Tempel, Carol A. Robbins, Linda C. Robinson, Helen M. Brew, Albee Messing
Publikováno v:
Journal of Neurophysiology. 98:1501-1525
Genes Kcna1 and Kcna2 code for the voltage-dependent potassium channel subunits Kv1.1 and Kv1.2, which are coexpressed in large axons and commonly present within the same tetramers. Both contribute to the low-voltage–activated potassium current IKv
Publikováno v:
Journal of Child and Family Studies. 16:760-772
Using symbolic interaction, we developed a research model that proposed adolescent perceptions of parental support and psychological control would be related to adolescent depressed mood directly and indirectly through self-esteem. We tested the mode
Autor:
Virginia M.-Y. Lee, John Q. Trojanowski, Michiyo Iba, George Xu, Gerard D. Schellenberg, Jeanna M. Wheeler, Murray A. Raskind, James B. Leverenz, Linda C. Robinson, Marc A. Dichter, Halvor Juul, Beth A. Dombroski, Michele Hawk, Elaine Loomis, Brian C. Kraemer, Pamela J. McMillan, Doori Jeong
Publikováno v:
Acta Neuropathologica Communications
Introduction Accumulation of insoluble conformationally altered hyperphosphorylated tau occurs as part of the pathogenic process in Alzheimer’s disease (AD) and other tauopathies. In most AD subjects, wild-type (WT) tau aggregates and accumulates i
Publikováno v:
Marriage & Family Review. 40:103-122
The purpose of this study was to examine how the relationship between adolescent perceptions of openness in parent-adolescent communication and adolescent empathy may differ by gender of the respondent. Hierarchical multiple regression analyses were
Publikováno v:
Journal of Divorce & Remarriage. 43:29-46
Using a symbolic interaction perspective, this study examined the extent to which (a) perceptions of parent/stepparent support were positively related to adolescent empathic concern and (b) perceptions of parent/stepparent psychological control media