Zobrazeno 1 - 10
of 472
pro vyhledávání: '"Linda C. Giudice"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-4 (2023)
Endometriosis is an incurable, under-diagnosed, systemic inflammatory disease affecting millions world-wide. Common symptoms include life-impacting pain, gastrointestinal/urinary symptoms, excessive fatigue, and infertility. Global public health poli
Externí odkaz:
https://doaj.org/article/c18a0ab882e94651a2cb9369d34bc541
Autor:
Tomiko T. Oskotsky, Arohee Bhoja, Daniel Bunis, Brian L. Le, Alice S. Tang, Idit Kosti, Christine Li, Sahar Houshdaran, Sushmita Sen, Júlia Vallvé-Juanico, Wanxin Wang, Erin Arthurs, Arpita Govil, Lauren Mahoney, Lindsey Lang, Brice Gaudilliere, David K. Stevenson, Juan C. Irwin, Linda C. Giudice, Stacy L. McAllister, Marina Sirota
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109388- (2024)
Summary: Existing medical treatments for endometriosis-related pain are often ineffective, underscoring the need for new therapeutic strategies. In this study, we applied a computational drug repurposing pipeline to stratified and unstratified diseas
Externí odkaz:
https://doaj.org/article/7cb7fa771de148cfb0ba716157579323
Autor:
Júlia Vallvé-Juanico, Ashley F. George, Sushmita Sen, Reuben Thomas, Min-Gyoung Shin, Divyashree Kushnoor, Joshua J. Vásquez, Kim Chi Vo, Juan C. Irwin, Nadia R. Roan, Alexis J. Combes, Linda C. Giudice
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Endometriosis is a chronic, estrogen-dependent disorder where inflammation contributes to disease-associated symptoms of pelvic pain and infertility. Immune dysfunction includes insufficient immune lesion clearance, a pro-inflamma
Externí odkaz:
https://doaj.org/article/3b2c8697a1e145c18977060f000edef6
Autor:
Daniel G. Bunis, Wanxin Wang, Júlia Vallvé-Juanico, Sahar Houshdaran, Sushmita Sen, Isam Ben Soltane, Idit Kosti, Kim Chi Vo, Juan C. Irwin, Linda C. Giudice, Marina Sirota
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
The uterine lining (endometrium) exhibits a pro-inflammatory phenotype in women with endometriosis, resulting in pain, infertility, and poor pregnancy outcomes. The full complement of cell types contributing to this phenotype has yet to be identified
Externí odkaz:
https://doaj.org/article/4733fe4718cf4973b6070d00bd323c92
Autor:
Junyu Zhai, Shang Li, Sushmita Sen, Jessica Opoku-Anane, Yanzhi Du, Zi-Jiang Chen, Linda C. Giudice
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Adenomyosis is a prevalent, estrogen-dependent uterine disorder wherein endometrial cells are abnormally present in the myometrium and are surrounded by hyperplastic/hypertrophic smooth muscle. Its etiology is unclear, although endometrial cell invas
Externí odkaz:
https://doaj.org/article/f8fbca6efe574c80bbff22471caee9dd
Autor:
Tongcui Ma, Xiaoyu Luo, Ashley F George, Gourab Mukherjee, Nandini Sen, Trimble L Spitzer, Linda C Giudice, Warner C Greene, Nadia R Roan
Publikováno v:
eLife, Vol 9 (2020)
The female reproductive tract (FRT) is the most common site of infection during HIV transmission to women, but viral remodeling complicates characterization of cells targeted for infection. Here, we report extensive phenotypic analyses of HIV-infecte
Externí odkaz:
https://doaj.org/article/e2465c199afb47b69b954f976129fd78
Autor:
Thalia R, Segal, Linda C, Giudice
Publikováno v:
Fertility and Sterility. 118:215-223
Climate change is a major risk factor for overall health, including reproductive health, and well-being. Increasing temperatures, due mostly to increased greenhouse gases trapping excess heat in the atmosphere, result in erratic weather patterns, wil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12496e7ca5158fac67821c8a952efae9
https://doi.org/10.1016/j.fertnstert.2022.06.005
https://doi.org/10.1016/j.fertnstert.2022.06.005
Autor:
Linda C, Giudice, Sawsan, As-Sanie, Juan C, Arjona Ferreira, Christian M, Becker, Mauricio S, Abrao, Bruce A, Lessey, Eric, Brown, Krzysztof, Dynowski, Krzysztof, Wilk, Yulan, Li, Vandana, Mathur, Qurratul Ann, Warsi, Rachel B, Wagman, Neil P, Johnson
Publikováno v:
The Lancet. 399:2267-2279
Endometriosis is a common cause of pelvic pain in women, for which current treatment options are suboptimal. Relugolix, an oral gonadotropin-releasing hormone receptor antagonist, combined with estradiol and a progestin, was evaluated for treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef8b035e5b8ac6678ca47b337a6a377
https://doi.org/10.1016/s0140-6736(22)00622-5
https://doi.org/10.1016/s0140-6736(22)00622-5
Publikováno v:
Fertility and Sterility.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b61f58717ee2a0853c0f54c2b8eb649e
https://doi.org/10.1016/j.fertnstert.2023.04.021
https://doi.org/10.1016/j.fertnstert.2023.04.021
Autor:
Linda C. Giudice, Richard O. Burney, Christian M. Becker, Stacey A. Missmer, Grant Montgomery, Nilufer Rahmioglu, Peter A.W. Rogers, Krina Zondervan
Publikováno v:
Human Reproductive and Prenatal Genetics ISBN: 9780323913805
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::716ce72191b5eeb51373d18161e2255b
https://doi.org/10.1016/b978-0-323-91380-5.00018-6
https://doi.org/10.1016/b978-0-323-91380-5.00018-6
