Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Linda Biadasz Clerch"'
Autor:
Emma Alexander, Kristin Reiland, Linda Biadasz Clerch, Eric P. Hoffman, Gloria DeCarlo Massaro, Donald Massaro
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 292:L1313-L1326
Alveolar regenerative gene expression is unidentified partly because its onset, after a regenerative stimulus, is unknown. Toward addressing this void, we used a mouse model in which calorie restriction produces alveolar loss, and ad libitum access t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd0e02150176de77dbdc486aa1c8779
https://doi.org/10.1152/ajplung.00146.2006
https://doi.org/10.1152/ajplung.00146.2006
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 287:L1066-L1070
A technically easy, noninvasive means of delivering molecules to alveoli, which act selectively or specifically in the lung, would be experimentally and therapeutically useful. As proof of principle, we took advantage of the spreading ability of pulm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bfa468e07fe05917936cef7844e0f2
https://doi.org/10.1152/ajplung.00067.2004
https://doi.org/10.1152/ajplung.00067.2004
Autor:
Eric P. Hoffman, Linda Biadasz Clerch, Alexander S. Baras, Gloria DeCarlo Massaro, Donald Massaro
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 286:L411-L419
Treatment of newborn mice with dexamethasone (Dex) inhibits the subdivision of lung saccules to form alveoli; treatment with all- trans retinoic acid (RA) prevents this inhibition of septation. To better understand the early molecular signals respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2eb8374c431074b273467831021692d
https://doi.org/10.1152/ajplung.00306.2003
https://doi.org/10.1152/ajplung.00306.2003
Autor:
Linda Knirsch, Linda Biadasz Clerch
Publikováno v:
Biochemistry. 40:7890-7895
All cells tested contain a cytosolic protein that binds to a defined region in the 3' untranslated region of manganese superoxide dismutase (MnSOD) RNA; both the MnSOD RNA-binding protein (MnSOD-BP) and the cis element are required for efficient tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2b854c1f2bc0f95c36cc3516ddaf91
https://doi.org/10.1021/bi010197n
https://doi.org/10.1021/bi010197n
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 276:L705-L708
Lipopolysaccharide (LPS) treatment increases survival of rats, but not of mice, during hyperoxia. Manganese superoxide dismutase (Mn SOD) in the lung plays a critical role in LPS-induced tolerance to hyperoxia in rats. Therefore, we now compared the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eedaff0ef08b7c268a00dcd98cbc5193
https://doi.org/10.1152/ajplung.1999.276.5.l705
https://doi.org/10.1152/ajplung.1999.276.5.l705
Publikováno v:
Biochemistry. 37:16298-16306
A redox-sensitive protein that binds to the 3' untranslated region (UTR) of manganese superoxide dismutase (MnSOD) RNA has been described previously [Fazzone, H., Wangner, A., and Clerch, L. B. (1993) J. Clin. Invest. 92, 1278-1281; Chung, D. J., and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ed91bcc1a4b67141b9d81905d48b8a
https://doi.org/10.1021/bi980935g
https://doi.org/10.1021/bi980935g
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 271:L875-L879
Treatment of rats with pertussis toxin (PTX) decreases the activity of manganese superoxide dismutase (Mn-SOD) in the lung and results in oxygen toxicity in air (L. B. Clerch, G. Neithardt, U. Spencer, J. A. Melendez, G. D. Massaro, and D. Massaro. J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ae5ff554353718661af2440db5e6c0
https://doi.org/10.1152/ajplung.1996.271.6.l875
https://doi.org/10.1152/ajplung.1996.271.6.l875
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 271:L949-L954
Lipopolysaccharide (LPS), a component of the cell wall of Gram-negative bacteria, interacts with eukaryotic cells, causing changes in gene expression and a rapid increase in the formation of superoxide and H2O2. We now report that, within 6 h of trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124d8ebe67988582a3e3bec417a3cc38
https://doi.org/10.1152/ajplung.1996.271.6.l949
https://doi.org/10.1152/ajplung.1996.271.6.l949
Publikováno v:
Biochemical and Biophysical Research Communications. 222:590-594
Rat lung extract contains protein that binds to a cis element in the 3′ untranslated region of glutathione peroxidase (GPx) mRNA; this region is located 200 bases downstream of the stop codon and 77 bases downstream of the selenocysteine insertion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9564f25ed43779f1905d01bf1968c9e2
https://doi.org/10.1006/bbrc.1996.0788
https://doi.org/10.1006/bbrc.1996.0788
Autor:
Donald Massaro, Gloria DeCarlo Massaro, U Spencer, Linda Biadasz Clerch, G Neithardt, J A Melendez
Publikováno v:
Journal of Clinical Investigation. 93:2482-2489
Exposure of rats to hyperoxia or to treatment with endotoxin, increases lung manganese superoxide dismutase (MnSOD) gene expression. However, the paths by which these environmental signals are transduced into enhanced MnSOD gene expression are unknow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a431e859e61ccbb2d3f0807df745fbdc
https://doi.org/10.1172/jci117257
https://doi.org/10.1172/jci117257