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Autor:
Ming Y. Chu, Mu-Ill Lim, Gerald W. Crabtree, Linda B. Zuckerman, Arthur E. Bogden, Seiji Sato, Robert S. Klein
Publikováno v:
Biochemical Pharmacology. 33:1229-1234
Deazaadenosine (9-DAA), a novel purine analog, was found to be a potent inhibitor of the growth of nine different human solid tumor cell lines in vitro and of pancreatic carcinoma (DAN) in antithymocyte serum (ATS)-immunosuppressed mice. In culture,