Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Linda B. S. Aulin"'
Autor:
Robin Michelet, Linda B. S. Aulin, Jens M. Borghardt, Teresa Dalla Costa, Paolo Denti, Manuel Ibarra, Guangda Ma, Bernd Meibohm, Goonaseelan (Colin) Pillai, Stephan Schmidt, Stefanie Hennig, Charlotte Kloft
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 6, Pp 743-747 (2023)
Externí odkaz:
https://doaj.org/article/d47a9342018b4215a7fc58031d099e10
Autor:
Linda B. S. Aulin, Apostolos Liakopoulos, Piet H. van der Graaf, Daniel E. Rozen, J. G. Coen van Hasselt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Collateral sensitivity-based antibiotic treatments may have the potential to limit the emergence of antimicrobial resistance. Here, the authors use mathematical modelling to study the effects of pathogen- and drug-specific characteristics for differe
Externí odkaz:
https://doaj.org/article/ee7918032aae4ee5bbcb1a37493613bc
Autor:
Alix Démaris, Ella S. K. Widigson, Johan F. K. F. Ilvemark, Casper Steenholdt, Jakob B. Seidelin, Wilhelm Huisinga, Robin Michelet, Linda B. S. Aulin, Charlotte Kloft
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2095 (2022)
Ulcerative colitis (UC) is part of the inflammatory bowels diseases, and moderate to severe UC patients can be treated with anti-tumour necrosis α monoclonal antibodies, including infliximab (IFX). Even though treatment of UC patients by IFX has bee
Externí odkaz:
https://doaj.org/article/c812f74b3f2b4d1bb8b4146dd2c21b1e
Autor:
Katie, Healy, Linda B S, Aulin, Urban, Freij, Marie, Ellerstad, Lena, Brückle, Helen, Hillmering, Tor-Einar, Svae, Kristina, Broliden, Rasmus, Gustafsson
Publikováno v:
The Journal of Infectious Diseases. 227:1214-1218
Background Asymptomatic blood donors can transmit human parvovirus B19 (B19V). Methods We assessed the B19V prevalence among a large cohort of blood donations collected in Germany during 2015–2018. Results In total, 167 123 donations were screened
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e18168b4e03167e7897a2f8cafdcc4
https://doi.org/10.1093/infdis/jiac456
https://doi.org/10.1093/infdis/jiac456
Autor:
Feiyan Liu, Linda B. S. Aulin, Tingjie Guo, Elke H. J. Krekels, Matthijs Moerland, Piet H. van der Graaf, Johan G. C. van Hasselt
Publikováno v:
British Journal of Clinical Pharmacology, 88(12), 5420-5427. WILEY
Clinical studies in healthy volunteers challenged with lipopolysaccharide (LPS), a constituent of the cell wall of Gram-negative bacteria, represent a key model to characterize the Toll-like receptor 4 (TLR4)-mediated inflammatory response. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876f10c699b57e7f3bf4c27b458a72f5
https://doi.org/10.1111/bcp.15476
https://doi.org/10.1111/bcp.15476
Autor:
Linda B. S. Aulin, Sebastian T. Tandar, Torben van Zijp, Etienne van Ballegooie, Piet H. van der Graaf, Mohammed A. A. Saleh, Pyry Välitalo, J. G. Coen van Hasselt
Publikováno v:
Clinical Pharmacokinetics, 61, 1735-1748
Prediction of antimicrobial target-site pharmacokinetics is of relevance to optimize treatment with antimicrobial agents. A physiologically based pharmacokinetic (PBPK) model framework was developed for prediction of pulmonary pharmacokinetics, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e786c8860f3e98f3e6e6266d4e4e78
https://pubmed.ncbi.nlm.nih.gov/36401151
https://pubmed.ncbi.nlm.nih.gov/36401151
Autor:
Feiyan Liu, Linda B. S. Aulin, Sebastiaan S. A. Kossen, Julius Cathalina, Marlotte Bremmer, Amanda C. Foks, Piet H. van der Graaf, Matthijs Moerland, Johan G. C. van Hasselt
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics, 49(6), 645-655
Sepsis is a life-threatening condition driven by the dysregulation of the host immune response to an infection. The complex and interacting mechanisms underlying sepsis remain not fully understood. By integrating prior knowledge from literature using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9089e834131675be66c066a2367c569e
https://pubmed.ncbi.nlm.nih.gov/36261775
https://pubmed.ncbi.nlm.nih.gov/36261775
Autor:
A. De Jaeger, W. Vandenberghe, P. De Paepe, Jacobus P.J. Ungerer, Evelyn Dhont, Brett McWhinney, J G C van Hasselt, Linda B. S. Aulin, P De Cock, J. Vande Walle
Publikováno v:
Clinical Pharmacokinetics. ADIS INT LTD
Clinical Pharmacokinetics
Clinical Pharmacokinetics
Background and Objectives Teicoplanin is a highly protein-bound antibiotic, increasingly used to treat serious Gram-positive infections in critically ill children. Maturational and pathophysiological intensive care unit-related changes often lead to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea02758d2d890f4d546492c23cb3d462
https://doi.org/10.1007/s40262-020-00945-4
https://doi.org/10.1007/s40262-020-00945-4
Autor:
Piet H. van der Graaf, Swantje Völler, Mohammed A A Saleh, Linda B. S. Aulin, J. G. Coen van Hasselt, Dylan W. de Lange
Publikováno v:
Clinical Pharmacology and Therapeutics, 110(2), 346-360
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics
Treatment failure of antibiotic therapy due to insufficient efficacy or occurrence of toxicity is a major clinical challenge, and is expected to become even more urgent with the global rise of antibiotic resistance. Strategies to optimize treatment i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e58f8b3d20c6939770831fad972008a
https://hdl.handle.net/1887/3216835
https://hdl.handle.net/1887/3216835
Autor:
J. G. Coen van Hasselt, Daniel E. Rozen, Apostolos Liakopoulos, Linda B. S. Aulin, Piet H. van der Graaf
Publikováno v:
Nature Communications, 12
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Collateral sensitivity (CS)-based antibiotic treatments, where increased resistance to one antibiotic leads to increased sensitivity to a second antibiotic, may have the potential to limit the emergence of antimicrobial resistance. However, it remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26444aafa2754cec41548a8587f9782e
http://hdl.handle.net/1887/3216859
http://hdl.handle.net/1887/3216859