Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Linda B. Mora"'
Publikováno v:
Cancer Diagn Progn
Background/Aim: Langerhans cell histiocytosis (LCH) is an uncommon disorder characterized by an abnormal monoclonal proliferation of pathologic Langerhans cells. The clinical presentation of LCH is very unpredictable, ranging from single-system limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178a1cb6c1b7332cf0349a3242aa1d00
https://europepmc.org/articles/PMC9801445/
https://europepmc.org/articles/PMC9801445/
Autor:
Michelle DeSilvio, Elizabeth H. Hammond, Richard Jove, R. Jeffrey Lee, Jeffrey D. Forman, Linda B. Mora, Howard M. Sandler, Alan Pollack, Nazeel Ahmad, Javier F. Torres-Roca, Li Yan Khor
Publikováno v:
Urology. 69:505-509
OBJECTIVE STAT3 participates in the regulation of cellular growth, survival, and oncogenesis. We evaluated the association between activated STAT3 expression and overall survival, disease-specific survival, distant metastasis, and local progression i
Publikováno v:
Journal of Biological Chemistry. 280:32979-32988
Previous studies have established constitutive activation of Stat3 protein as one of the molecular changes required for tumorigenesis. To develop novel therapeutics for tumors harboring constitutively active Stat3, compounds from the NCI 2000 diversi
Autor:
Bin Yu, Linda B. Mora, Ralf Buettner, Richard Jove, Eric B. Haura, Daniel J Dauer, Bernadette Ferraro, Lanxi Song, Steve Enkemann
Publikováno v:
Oncogene. 24:3397-3408
Wound healing and cancer are both characterized by cell proliferation, remodeling of extracellular matrix, cell invasion and migration, new blood vessel formation, and modulation of blood coagulation. The mechanisms that link wound healing and cancer
Publikováno v:
Cancer Control. 8:551-561
Adenocarcinoma of the prostate gland presents with a wide variety of clinical findings, ranging from asymptomatic, relatively latent tumors to highly aggressive, metastasizing cancers. Tumors predominantly arise from epithelial cells in the periphera
Autor:
Linda B. Mora, Santo V. Nicosia, George Marcet, Richard C. Karl, Timothy J. Yeatman, Domenico Coppola, Li Lu, Ardeshir Hakam
Publikováno v:
Human Pathology. 30:1128-1133
The activation of the insulinlike growth factor 1/IGF-1 receptor system (IGF1/IGF1-R) has recently emerged as critical event in transformation and tumorigenicity of several murine and human tumors. Expression of IGF1 and of IGF1-R has been demonstrat
Autor:
Jose I. Diaz, Linda B. Mora, Alan B. Cantor, Julio M. Pow-Sang, Santo V. Nicosia, Carlos A. Muro-Cacho, Paul F. Austin
Publikováno v:
Urology. 53:931-938
Objectives. To evaluate the relationship of DNA ploidy and cell proliferation (CP) with Gleason score (GS) and clinical outcome in prostate cancer. Methods. Sixteen patients with benign prostatic hyperplasia (BPH) and 65 patients with prostate cancer
Publikováno v:
Annals of Surgical Oncology. 6:298-304
Background: Barrett’s esophagus (BE) is a premalignant lesion characterized by replacement of normal squamous epithelium with columnar epithelium. This lesion can progress to dysplasia and adenocarcinoma. Recently, the Fas receptor and retinoblasto
Autor:
Jia-Wang Wang, W. Douglas Cress, Joshua J. Gamsby, William G. Kerr, Linda B. Mora, Tim J Yeatman, Lewis A. Chodosh, Tien-chi Pan, Anna L Ramne, Steven L. Highfill, Jiandong Chen, Gregory C. Bloom
Publikováno v:
Oncogene. 23(23)
LRBA expression is induced by mitogens in lymphoid and myeloid cells. The Drosophila LRBA orthologue rugose/DAKAP550 is involved in Notch, Ras and EGFR pathways. These findings suggest that LRBA could play a role in cell types that have increased pro
Autor:
Lyudmila, Burdelya, Robyn, Catlett-Falcone, Alexander, Levitzki, Fengdong, Cheng, Linda B, Mora, Eduardo, Sotomayor, Domenico, Coppola, JiaZhi, Sun, Said, Sebti, William S, Dalton, Richard, Jove, Hua, Yu
Publikováno v:
Molecular cancer therapeutics. 1(11)
Constitutive activation of Janus kinases (JAKs) and signal transducers and activators of transcription (STAT) occurs at very high frequency in various hematopoietic malignancies and solid tumors. It has been demonstrated that the tyrosine kinase inhi