Výsledky vyhledávání - "Linda B. Clerch"

Rat lung peroxiredoxins I and II are differentially regulated during development and by hyperoxia

Autor: Linda B. Clerch, Sue Goo Rhee, Sang Won Kang, Han Suk Kim

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 280:L1212-L1217

Peroxiredoxin I (Prx I) and peroxiredoxin II (Prx II) are found in abundance in the cytoplasm of cells and catalyze the reduction of hydrogen peroxide with the use of electrons provided by thioredoxin. Here we examined Prx I and Prx II expression in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9c56d51c9f535e9039536d938f38ed
https://doi.org/10.1152/ajplung.2001.280.6.l1212

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Estrogen Regulates Angiotensin AT1 Receptor Expression via Cytosolic Proteins that Bind to the 5′ Leader Sequence of the Receptor mRNA

Autor: Joseph G. Verbalis, Kathryn Sandberg, Wei Zheng, Linda B. Clerch, Kamakshi Krishnamurthi, Zheng Wu

Publikováno v: Endocrinology. 140:5435-5438

Two of the most highly recognized factors implicated in the pathogenesis of hypertension, atherosclerosis, congestive heart failure and associated cardiovascular disease are the renin angiotensin system (RAS) and estrogen. A major effect of estrogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3acbdc4db0fda7e4fd018b3bd4a56245
https://doi.org/10.1210/endo.140.11.7242

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Kidney Extracts from Spontaneously Hypertensive Rats (Shr) Have Greater Dopamine 1A Receptor Rna-Binding Activity Than Extracts from Normotensive Wistar-Kyoto (Wky) Rats

Autor: Angelique Wright, Linda B. Clerch, Elizabeth Slobodyansky, M. Maral Mouradian, Pedro A. Jose, Wei Wang

Publikováno v: Scopus-Elsevier

Rat kidney extracts contain a 52 kDa protein that binds to the 3' untranslated region of the dopamine 1A (D1A) receptor mRNA at a 243 base-long cis element starting at the stop codon and ending approximately 220 bases upstream of an AUUUA-rich region

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b88eaaba3088b74751b812a1a245464
https://doi.org/10.3109/10641969709083202

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Increased manganese superoxide dismutase activity, protein, and mRNA levels and concurrent induction of tumor necrosis factor α in radiation-initiated Syrian hamster cells

Autor: D. Massaro, Dimitris Emfietzoglou, Vicente Notario, Gabriel Otero, Linda B. Clerch, Matías A. Avila

Publikováno v: Molecular Carcinogenesis. 17:175-180

The levels of the antioxidant enzyme manganese superoxide dismutase (Mn-SOD) are frequently decreased in tumor cells and increased in normal cells upon treatment with ionizing radiation. We studied Mn-SOD at different stages during the neoplastic con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::237a73209116226723246e0bad2227f5
https://doi.org/10.1002/(sici)1098-2744(199612)17:4<175::aid-mc1>3.0.co

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Dinucleotide-binding site of bovine liver catalase mimics a catalase mRNA-binding protein domain

Autor: Linda B. Clerch, Angelique Wright, D. Massaro

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 270:L790-L794

Rat lung contains protein that interacts with catalase mRNA to form specific, redox-sensitive RNA-protein complexes. The studies in this report were aimed at determining whether catalase protein binds its own RNA. We found that rat catalase RNA binds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04105d782773a9db835d3ba3ee0e77b0
https://doi.org/10.1152/ajplung.1996.270.5.l790

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Lung Manganese Superoxide Dismutase Protein Expression Increases in the Baboon Model of Bronchopulmonary Dysplasia and Is Regulated at a Posttranscriptional Level

Autor: Angelique E Wright, Linda B. Clerch, Jacqueline J. Coalson

Publikováno v: Pediatric Research. 39:253-258

The expression of lung manganese superoxide dismutase (MnSOD) mRNA and protein were examined in a premature baboon model of hyperoxia-induced bronchopulmonary dysplasia (BPD) and BPD superimposed with bacterial infection. When 140-d gestation baboons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ed61ed3baffabdb5e39de8d6823b42
https://doi.org/10.1203/00006450-199602000-00011

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Perinatal rat lung catalase gene expression: influence of corticosteroid and hyperoxia

Autor: D. Massaro, J. Iqbal, Linda B. Clerch

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 260:L428-L433

Dexamethasone accelerates the late gestational rise in rat lung catalase activity; neonatal hyperoxia elevates rat lung catalase activity. We studied the regulation of catalase gene expression in these instances. Catalase mRNA/mg DNA increased to ges

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b04cecce4452a443d5c0f5f5f9a830
https://doi.org/10.1152/ajplung.1991.260.6.l428

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Rat lung antioxidant enzymes: differences in perinatal gene expression and regulation

Autor: Linda B. Clerch, D. Massaro

Publikováno v: The American journal of physiology. 263(4 Pt 1)

The lung activity of the antioxidant enzymes (AOEs) copper, zinc superoxide dismutase (Cu,Zn SOD), catalase (CAT), and glutathione peroxidase (GP), but not manganese superoxide dismutase (Mn SOD), increases in rats during late gestation; the concentr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be7700fc8a80ba24dbb3d6287d5342f
https://pubmed.ncbi.nlm.nih.gov/1415724

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