Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Linda B. Buck"'
Autor:
Eun Jeong Lee, Luis R. Saraiva, Naresh K. Hanchate, Xiaolan Ye, Gregory Asher, Jonathan Ho, Linda B. Buck
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Scents have been employed for millennia to allay stress, but whether or how they might do so is largely unknown. Fear and stress induce increases in blood stress hormones controlled by hypothalamic corticotropin releasing hormone neurons (CR
Externí odkaz:
https://doaj.org/article/7d6690be1ef74927bdba2cdf0bddb2ba
Autor:
Donghui Kuang, Naresh K. Hanchate, Chia-Ying Lee, Ashley Heck, Xiaolan Ye, Michidsaran Erdenebileg, Linda B. Buck
Publikováno v:
bioRxiv
The sense of smell has potent effects on appetite, but the underlying neural mechanisms are largely a mystery. The hypothalamic arcuate nucleus contains two subsets of neurons linked to appetite: AgRP (agouti-related peptide) neurons, which enhance a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6bca3c305c5550b14038c699c143a0
https://doi.org/10.1101/2023.02.28.530282
https://doi.org/10.1101/2023.02.28.530282
Autor:
Donghui Kuang, Andria Ellis, Eun-Jeong Lee, Cole Trapnell, Ryan Basom, Kunio Kondoh, Naresh Kumar Hanchate, Linda B. Buck
Publikováno v:
Proc Natl Acad Sci U S A
The mouse brain contains ~100 million neurons interconnected in a vast array of neural circuits. The identities and functions of individual neuronal components of most circuits are undefined. Here we describe a method, termed ‘Connect-seq’, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd8836273f44e3cc969d6a72ebe4cb7
https://doi.org/10.1073/pnas.1912176117
https://doi.org/10.1073/pnas.1912176117
Autor:
Xiaolan Ye, Gregory Asher, Linda B. Buck, Eun-Jeong Lee, Luis R. Saraiva, Naresh Kumar Hanchate, Jonathan Ho
Scents have been employed for millennia to allay fear and stress, but whether they do so is poorly understood. In response to fear and stress, hypothalamic corticotropin releasing hormone neurons (CRHNs) induce increases in blood stress hormones. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b788752a80f4102491ab65fec9e4fe19
https://doi.org/10.1101/2021.02.24.432809
https://doi.org/10.1101/2021.02.24.432809
Autor:
Naresh Kumar Hanchate, Linda B. Buck, Ryan Basom, Cole Trapnell, Donghui Kuang, Andria Ellis, Eun-Jeong Lee, Kunio Kondoh
Publikováno v:
Journal of the Endocrine Society
Animals exhibit instinctive behavioral and physiological responses to a variety of stressors to overcome danger and restore homeostasis. The physiological response to stress is governed by hypothalamic corticotropin-releasing hormone (CRH) neurons wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0c05277d9f6977d99550c5b7ecdebc
http://europepmc.org/articles/PMC7208927
http://europepmc.org/articles/PMC7208927
Autor:
Xiaolan Ye, Ai Phuong S. Tong, Linda B. Buck, Eun-Jeong Lee, Kunio Kondoh, Donghui Kuang, Naresh Kumar Hanchate, Andrew Spray
Publikováno v:
Science Advances
New studies show that POMC neurons linked to appetite suppression also play a key role in stress hormone responses.
Mammals exhibit instinctive reactions to danger critical to survival, including surges in blood stress hormones. Hypothalamic cor
Mammals exhibit instinctive reactions to danger critical to survival, including surges in blood stress hormones. Hypothalamic cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e90980747ecf59fe74f18401eaee689
https://doi.org/10.1016/j.ibror.2019.07.1621
https://doi.org/10.1016/j.ibror.2019.07.1621
Publikováno v:
Aging Cell
One goal of aging research is to find drugs that delay the onset of age-associated disease. Studies in invertebrates, particularly Caenorhabditis elegans, have uncovered numerous genes involved in aging, many conserved in mammals. However, which of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4a5de3f80762f531d3b80efba87a6a
https://doi.org/10.1111/acel.12163
https://doi.org/10.1111/acel.12163
Publikováno v:
Proceedings of the National Academy of Sciences. 113
The mechanisms by which odors induce instinctive behaviors are largely unknown. Odor detection in the mouse nose is mediated by >1, 000 different odorant receptors (ORs) and trace amine-associated receptors (TAARs). Odor perceptions are encoded combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c86385c1431a4b927a7bf33a8c0912
https://doi.org/10.1073/pnas.1605973113
https://doi.org/10.1073/pnas.1605973113
Instinctive reactions to danger are critical to the perpetuation of species and are observed throughout the animal kingdom. The scent of predators induces an instinctive fear response in mice that includes behavioural changes, as well as a surge in b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263a9e95b397b86f5dc9cc573bea5825
https://europepmc.org/articles/PMC5094457/
https://europepmc.org/articles/PMC5094457/
Publikováno v:
Journal of Neuroscience. 31:9179-9191
Mammals can perceive and discriminate myriad volatile chemicals as having a distinct odor. Odorants are initially detected by odorant receptors (ORs) on olfactory sensory neurons (OSNs) in the nose. In the mouse, each OSN expresses one of ∼1000 dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a6cc2580701b54b773957a572d8d13
https://doi.org/10.1523/jneurosci.1282-11.2011
https://doi.org/10.1523/jneurosci.1282-11.2011