Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Linda A. Verkruyse"'
Publikováno v:
Bone Marrow Transplantation. 37:51-56
Quantitative polymerase chain reaction (QPCR) for cytomegalovirus (CMV) is emerging as the preferred screening method for detection of CMV viremia in patients following allogeneic bone marrow and peripheral blood stem cell transplant. However, there
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1583:35-44
Fatty acylation of proteins on cysteine residues is a common post-translational modification that plays roles in protein–membrane and protein–protein interactions. Recently, we described a lysosomal palmitoyl-protein thioesterase that removes lon
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1361:1-5
Mutations in the gene encoding a recently described lysosomal enzyme, palmitoyl-protein thioesterase (PPT), have recently been shown to result in the neurodegenerative disorder, infantile neuronal ceroid lipofuscinosis (INCL). Reduced palmitoyl-prote
Publikováno v:
Neuropediatrics. 28:27-30
Palmitoyl-protein thioesterase (PPT) has recently been shown to be the defective enzyme underlying the infantile form of neuronal ceroid lipofuscinosis (INCL). In this paper, we review the enzymology of PPT, evidence for its localization in lysosomes
Autor:
Linda A. Verkruyse, Sandra L. Hofmann
Publikováno v:
Journal of Biological Chemistry. 271:15831-15836
Palmitoyl-protein thioesterase is a newly described long chain fatty-acid hydrolase that removes fatty acyl groups from modified cysteines in proteins. We have recently identified palmitoyl-protein thioesterase as the defective enzyme in the recessiv
Autor:
Leena Peltonen, Juhani Rapola, Pirkko Santavuori, Hellsten E, Jouni Vesa, Linda A. Verkruyse, Laura A. Camp, Sandra L. Hofmann
Publikováno v:
Nature. 376:584-587
NEURONAL ceroid lipofuscinoses (NCL) represent a group of common progressive encephalopathies of children which have a global incidence of 1 in 12,500 (ref. 1). These severe brain diseases are divided into three autosomal recessive subtypes, assigned
Publikováno v:
Journal of Biological Chemistry. 269:23212-23219
We have previously reported the purification of a palmitoyl-protein thioesterase (PPT) from bovine brain that removes palmitate from Ha-Ras (Camp, L. A., and Hofmann, S. L. (1993) J. Biol. Chem. 268, 22566-22574). In the current paper, we have isolat
Autor:
Ravi Vij, Armin Ghobadi, Peter Westervelt, Keith Stockerl-Goldstein, K. Trinkaus, Camille N. Abboud, Geoffrey L. Uy, Linda A. Verkruyse, J.S. Chawla, John F. DiPersio, Amanda F. Cashen, James C. Mosley
Publikováno v:
Transplant infectious disease : an official journal of the Transplantation Society. 14(3)
Background Cytomegalovirus (CMV) infection is an important cause of morbidity and mortality after allogeneic hematopoietic stem cell transplant (HSCT). This pilot prospective randomized clinical trial compares valganciclovir (VGV) to ganciclovir (GCV
Publikováno v:
Journal of Magnetic Resonance (1969). 88:609-614
NMR pulsed-field-gradient (PFG) diffusion measurements have emerged as a quick and simple technique for measuring self-diffusion coefficients of fluids. This technique has been shown to be useful for probing the structures of ordered fluids such as s